LOCUS BC072406 3484 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens dual serine/threonine and tyrosine protein kinase,
mRNA (cDNA clone MGC:88075 IMAGE:6138109), complete cds.
ACCESSION BC072406
VERSION BC072406.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3484)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3484)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 174 Row: i Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40806180.
FEATURES Location/Qualifiers
source 1..3484
/db_xref="H-InvDB:HIT000264851"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:88075 IMAGE:6138109"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3484
/gene="DSTYK"
/gene_synonym="DustyPK"
/gene_synonym="HDCMD38P"
/gene_synonym="RIP5"
/db_xref="GeneID:25778"
/db_xref="HGNC:HGNC:29043"
/db_xref="MIM:612666"
CDS 9..2798
/gene="DSTYK"
/gene_synonym="DustyPK"
/gene_synonym="HDCMD38P"
/gene_synonym="RIP5"
/codon_start=1
/product="dual serine/threonine and tyrosine protein
kinase"
/protein_id="AAH72406.1"
/db_xref="GeneID:25778"
/db_xref="HGNC:HGNC:29043"
/db_xref="MIM:612666"
/translation="MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQN
LRETQKFFRDIKCSHNHTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEK
YLQQIVDCLPCILILGQDCNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQ
TRVSLALPGQYELVHTLVAHQGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQ
EVDVVVAPCQGLRPTVDVLGDLVNDFLPAITYALHKDELSERDEQELQEIRKYFSFPV
FFFKVPKLGSEIIDSSTRRMESERSPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLV
EQSEKLRHLSTFSHQVLQTRLVDAAKALNLVHCHCLDIFINQAFDMQRDLQITPKRLE
YTRKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDATNMEFKDVIVPENGE
PVGTREIKCCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQSLEKSQDV
SVHITSNYLKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVSPPAITLEWKR
KVAQEAIESLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLR
VRKDHAPRLARLSLESRSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKS
VVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSIAVLLIMERLHRD
LYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGF
CKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYICSGSVKLPEAFERCA
SKDHLWNNVRRGARPERLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLQGIMNRLC
KSNSEQPNRGLDDST"
BASE COUNT 879 a 843 c 942 g 820 t
ORIGIN
1 cagaggcgat ggagggcgac ggggtgccat ggggcagcga gcccgtctcg ggtcccggcc
61 ccggcggcgg cggaatgatc cgcgagctgt gccggggctt cggccgctac cgccgctacc
121 tgggacggct gcgacagaac ctgcgcgaga cccagaagtt cttccgcgac atcaagtgct
181 cccacaacca cacttgtctc tcctccctca cgggcggcgg cggggccgag cgcggccctg
241 caggcgatgt cgccgaaacc gggctgcagg cgggccaact gagctgcatt tccttcccac
301 ctaaggaaga gaagtacctc cagcagattg tggactgcct cccttgcata ctgatcctcg
361 gccaggattg taacgtcaag tgccagctgt tgaatctgct gttgggggtg caggtgcttc
421 ccaccaccaa gctgggcagt gaggagagct gtaagcttcg gcgcctccgc ttcacctatg
481 ggactcagac tcgggtcagc ctggcgctcc ctggacagta tgaactagtg cacacgctgg
541 ttgctcatca gggcaactgg gagaccatcc ctgaggagga tctggaggtc caagagaaca
601 atgaggatgc tgctcatgtt ttagcggaac tggaggtaac gatgcaccat gctctcttac
661 aggaagtgga cgttgtggta gcaccatgcc aaggcctccg gcccacagtg gatgttctgg
721 gtgacttggt gaatgatttc ttgcctgcga taacctatgc actccacaaa gatgaactct
781 ctgagaggga tgagcaagag cttcaggaaa tccgaaagta tttctccttt cctgtattct
841 ttttcaaagt gccgaaactg ggctcggaga taatagactc ctcaaccagg agaatggaga
901 gcgaaagatc accgctttat cgccagctaa ttgacctggg ctatctgagc agcagtcact
961 ggaactgtgg ggctcctggc caggatacta aagctcagag catgttggtg gaacagagtg
1021 aaaagctgag acacttgagc acattttctc accaggtgtt acagactcgc ctggtggatg
1081 cagccaaggc cctgaacctg gtgcactgcc actgccttga catctttatt aaccaggcat
1141 ttgacatgca gcgggacctg cagatcactc ccaaacgtct ggaatatact cgaaaaaagg
1201 agaatgagtt gtatgaatca ttgatgaata ttgccaaccg aaagcaggag gaaatgaagg
1261 atatgattgt tgagacactt aataccatga aggaggaact tctggatgat gctactaaca
1321 tggagtttaa agacgtcatt gtccctgaga atggagaacc agtaggcacc agagagatca
1381 aatgctgcat ccgacagatc caggaactca tcatctcccg acttaatcag gcagtggcta
1441 ataagctgat cagctcagtg gattacctga gggaaagctt cgtcggaacc ctggaacgat
1501 gtctgcagag cctggagaag tctcaggatg tctcagttca catcaccagt aattatctca
1561 aacagatctt aaatgctgcc tatcatgttg aagtcacgtt tcactcaggg tcgtcagtta
1621 caaggatgct atgggagcaa atcaaacaga tcatccagcg catcacatgg gtgagcccac
1681 ctgccatcac tctggaatgg aagaggaagg tggcccagga agccattgag agcctcagcg
1741 cctccaaatt ggctaagagc atttgcagcc aattccggac tcggctcaat agttcccacg
1801 aggcttttgc agcctccttg cggcagctgg aagctggcca ctcaggccgg ttagagaaaa
1861 cggaagatct atggctgagg gttcggaaag atcatgctcc ccgcctggcc cgcctttctc
1921 tggaaagccg ttctttacag gatgtcttgc ttcatcgtaa acctaaactg ggacaggaac
1981 tgggccgggg ccagtatggt gtggtatacc tgtgtgacaa ctggggagga cactttcctt
2041 gtgccctcaa atcagttgtc cctccagatg agaagcactg gaatgatctg gctttggaat
2101 ttcactatat gaggtctctg ccgaagcatg agcgattggt ggatctccat ggttcagtca
2161 ttgactacaa ctatggtggt ggctccagca ttgctgtgct cctcattatg gagcggctac
2221 accgggatct ctacacaggg ctgaaggctg ggctgaccct ggagacacgt ttgcagatag
2281 cactagatgt ggtggaggga atccgcttcc tgcacagcca gggacttgtc catcgtgata
2341 tcaaactgaa aaatgtgctg ctggataagc agaaccgtgc caagatcact gacttaggat
2401 tctgcaagcc agaggccatg atgtcaggca gcattgtggg gacaccaatc catatggccc
2461 ctgaactttt cacagggaag tacgataatt ccgtggatgt ctacgctttt ggaattcttt
2521 tctggtatat ctgctcaggc tctgtcaagc tccctgaggc atttgagagg tgtgctagca
2581 aagaccatct ctggaacaat gtgcggaggg gggctcgccc agaacgtctt cctgtgtttg
2641 atgaggagtg ctggcagttg atggaagcct gttgggatgg cgaccccttg aagaggcctc
2701 tcttgggcat tgtccagccc atgctccagg gcatcatgaa tcggctctgc aagtccaatt
2761 ctgagcagcc aaacagagga ctagatgatt ctacttgaaa gcaaagacct ttctctttca
2821 ctctctagtt atttccttcc ccctcacctt ttggccatgg ggagaatttg acatttattc
2881 actataggac acactcccaa gggaactggt gcttgctggg aaacttggaa ccttcccagg
2941 cagggatgac tcctggacag tgaagagttg aatgactgag catattcagc agctcactga
3001 agcgccaagc tatcccttta gcaaaaaagt gtctcagatg tgtaaaagct gaggaatgtg
3061 gtgttctggc ttcacaaatg aaaaggaggc agatgttacc attgtctttt cactgtatat
3121 acttctaaga cagcaagcgg gacactgcag tggcaatagt gttaaaaaat ctcattctca
3181 tgatttttgg ctctagctag gaatagttta gtcaggactc agaaaatttg agcttagttc
3241 tgggattatg aaaacatggg gacaaaaaca ataacttgtg gatgtctggt tcctgctgtc
3301 tgcagccagg tatctcaggt tgcaatggtc agaagtccca gtgagggagc tagaaacaga
3361 gctatctgtt cctcatagtg ccagtgtgtt tacatttata ggaccacata tccctggttt
3421 ctgggggagg gtttcactgt tacatcacca agaggccctg aaaagaggaa aaaaaaaaaa
3481 aaaa
//