LOCUS BC072017 1462 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens keratin 18, mRNA (cDNA clone MGC:88728 IMAGE:6251574),
complete cds.
ACCESSION BC072017
VERSION BC072017.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1462)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1462)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 58 Row: j Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40354194.
FEATURES Location/Qualifiers
source 1..1462
/db_xref="H-InvDB:HIT000264820"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:88728 IMAGE:6251574"
/tissue_type="Pancreas, ductal carcinoma"
/clone_lib="NIH_MGC_110"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1462
/gene="KRT18"
/gene_synonym="CYK18"
/gene_synonym="K18"
/db_xref="GeneID:3875"
/db_xref="HGNC:HGNC:6430"
/db_xref="MIM:148070"
CDS 46..1338
/gene="KRT18"
/gene_synonym="CYK18"
/gene_synonym="K18"
/codon_start=1
/product="keratin 18"
/protein_id="AAH72017.1"
/db_xref="GeneID:3875"
/db_xref="HGNC:HGNC:6430"
/db_xref="MIM:148070"
/translation="MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGS
RISVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLE
TENRRLESKIREHLEKKGPQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLA
ADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHE
EEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIE
ESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQ
MEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNL
GDALDSSNSMQTIQKTTTRRIVDGKVVSETNDTKVLRH"
BASE COUNT 410 a 390 c 424 g 238 t
ORIGIN
1 cgtccgcaaa gcctgagtcc tgtcctttct ctctccccgg acagcatgag cttcaccact
61 cgctccacct tctccaccaa ctaccggtcc ctgggctctg tccaggcgcc cagctacggc
121 gcccggccgg tcagcagcgc ggccagcgtc tatgcaggcg ctgggggctc tggttcccgg
181 atctccgtgt cccgctccac cagcttcagg ggcggcatgg ggtccggggg cctggccacc
241 gggatagccg ggggtctggc aggaatggga ggcatccaga acgagaagga gaccatgcaa
301 agcctgaacg accgcctggc ctcttacctg gacagagtga ggagcctgga gaccgagaac
361 cggaggctgg agagcaaaat ccgggagcac ttggagaaga agggacccca ggtcagagac
421 tggagccatt acttcaagat catcgaggac ctgagggctc agatcttcgc aaatactgtg
481 gacaatgccc gcatcgttct gcagattgac aatgcccgtc ttgctgctga tgactttaga
541 gtcaagtatg agacagagct ggccatgcgc cagtctgtgg agaacgacat ccatgggctc
601 cgcaaggtca ttgatgacac caatatcaca cgactgcagc tggagacaga gatcgaggct
661 ctcaaggagg agctgctctt catgaagaag aaccacgaag aggaagtaaa aggcctacaa
721 gcccagattg ccagctctgg gttgaccgtg gaggtagatg cccccaaatc tcaggacctc
781 gccaagatca tggcagacat ccgggcccaa tatgacgagc tggctcggaa gaaccgagag
841 gagctagaca agtactggtc tcagcagatt gaggagagca ccacagtggt caccacacag
901 tctgctgagg ttggagctgc tgagacgacg ctcacagagc tgagacgtac agtccagtcc
961 ttggagatcg acctggactc catgagaaat ctgaaggcca gcttggagaa cagcctgagg
1021 gaggtggagg cccgctacgc cctacagatg gagcagctca acgggatcct gctgcacctt
1081 gagtcagagc tggcacagac ccgggcagag ggacagcgcc aggcccagga gtatgaggcc
1141 ctgctgaaca tcaaggtcaa gctggaggct gagatcgcca cctaccgccg cctgctggaa
1201 gatggcgagg actttaatct tggtgatgcc ttggacagca gcaactccat gcaaaccatc
1261 caaaagacca ccacccgccg gatagtggat ggcaaagtgg tgtctgagac caatgacacc
1321 aaagttctga ggcattaagc cagcagaagc agggtaccct ttggggagca ggaggccaat
1381 aaaaagttca gagttcattg gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1441 aaaaaaaaaa aaaaaaaaaa aa
//