LOCUS BC071757 1793 bp mRNA linear HUM 02-DEC-2006
DEFINITION Homo sapiens homogentisate 1,2-dioxygenase (homogentisate oxidase),
mRNA (cDNA clone MGC:88318 IMAGE:6714217), complete cds.
ACCESSION BC071757
VERSION BC071757.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1793)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1793)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: NCI
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 57 Row: m Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504380.
FEATURES Location/Qualifiers
source 1..1793
/db_xref="H-InvDB:HIT000264577_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:88318 IMAGE:6714217"
/tissue_type="Pooled, 40 cell lines"
/clone_lib="NIH_MGC_127"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1793
/gene="HGD"
/gene_synonym="HGO"
/db_xref="GeneID:3081"
/db_xref="HGNC:HGNC:4892"
/db_xref="MIM:607474"
CDS 99..1436
/gene="HGD"
/gene_synonym="HGO"
/codon_start=1
/product="homogentisate 1,2-dioxygenase (homogentisate
oxidase)"
/protein_id="AAH71757.1"
/db_xref="GeneID:3081"
/db_xref="HGNC:HGNC:4892"
/db_xref="MIM:607474"
/translation="MAELKYISGFGNECSSEDPRCPGSLPEGQNNPQVCPYNLYAEQL
SGSAFTCPRSTNKRSWLYRILPSVSHKPFESIDEGHVTHNWDEVDPDPNQLRWKPFEI
PKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFLIVPQK
GNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGPIGA
NGLANPRDFLIPIAWYEDRQVPGGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPYK
YNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYY
HRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTMTPHGPDADCFEKASKVKLAPERIA
DGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLKSHFTPNSRNPAEPN"
BASE COUNT 581 a 371 c 401 g 440 t
ORIGIN
1 aatatccaaa gagtggtttg aaggagaaag aagcattgtg gctttatatc ctctgggcct
61 gggtttcctg aagtcaccac acatagagga gagagaaaat ggctgagtta aagtacattt
121 ctggatttgg gaatgagtgt tcttcagagg atcctcgctg cccaggttcc ctgccagaag
181 gacagaataa tcctcaggtc tgcccctaca atctctatgc tgagcagctc tcaggatcgg
241 ctttcacttg tccacggagc accaataaga gaagctggct gtataggatt ctaccttcag
301 tttctcacaa gccctttgaa tccattgacg aaggccatgt cactcacaac tgggatgaag
361 ttgatcctga tcctaaccag cttagatgga aaccatttga gattccaaaa gcatctcaga
421 agaaagtaga ctttgtgagt ggcctgcata ccttgtgtgg agctggagac ataaagtcta
481 acaatgggct tgctatccac attttcctct gcaatacctc catggagaac agatgctttt
541 acaattcaga tggggacttc ttgattgttc cgcagaaagg gaaccttctc atttacaccg
601 agtttggcaa gatgcttgta cagcccaatg agatctgcgt cattcagaga ggaatgcggt
661 tcagcataga tgtctttgag gagaccaggg gctacatctt ggaggtctat ggtgtccact
721 ttgagttacc tgaccttgga ccaattgggg ccaatggctt ggccaatcct cgtgatttct
781 tgatacccat tgcctggtat gaggatcgcc aagtaccagg tggttacacg gtcattaata
841 aataccaggg caagctgttt gctgccaaac aggatgtctc cccgttcaat gttgtggcct
901 ggcacgggaa ttatacaccc tacaagtaca acctgaagaa tttcatggtt atcaactcag
961 tggcctttga ccatgcagac ccatccattt tcacagtatt gactgctaag tctgtccgcc
1021 ctggagtggc cattgctgat tttgtcatct tcccacctcg atggggggtt gctgataaga
1081 ccttcaggcc tccttattac cataggaact gcatgagtga gttcatggga ctcatccgag
1141 gtcactatga ggcaaagcaa ggtgggttcc tgccaggggg agggagtcta cacagcacaa
1201 tgacccccca tggacctgat gctgactgct ttgagaaggc cagcaaggtc aagctggcac
1261 ctgagaggat tgccgatggc accatggcat ttatgtttga atcatcttta agtctggcgg
1321 tcacaaagtg gggactcaag gcctccaggt gtttggatga gaactaccac aagtgctggg
1381 agccactcaa gagccacttc actcccaact ccaggaaccc agcagaacct aattgagact
1441 ggaacattgc taccataatt aagagtagat ttgtgaagat ttcttcagaa tctcatgctt
1501 tctggtagta ttggaggagg gggttggtta aaatgaaaat tcacttttca tagtcaagta
1561 actcagaact tttatggaaa cgcatttgca aagttctatg gctgtcacct taattactca
1621 ataaacttgc tggtgttctg tggaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1681 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1741 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
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