LOCUS BC071596 4782 bp mRNA linear HUM 22-AUG-2008
DEFINITION Homo sapiens DENN/MADD domain containing 5A, mRNA (cDNA clone
MGC:87473 IMAGE:30348530), complete cds.
ACCESSION BC071596
VERSION BC071596.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4782)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4782)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 168 Row: p Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 44889474.
FEATURES Location/Qualifiers
source 1..4782
/db_xref="H-InvDB:HIT000264425"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87473 IMAGE:30348530"
/tissue_type="Placenta, pre-eclamptic"
/clone_lib="NIH_MGC_148"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4782
/gene="DENND5A"
/db_xref="GeneID:23258"
/db_xref="HGNC:HGNC:19344"
CDS 63..3926
/gene="DENND5A"
/codon_start=1
/product="DENN/MADD domain containing 5A"
/protein_id="AAH71596.1"
/db_xref="GeneID:23258"
/db_xref="HGNC:HGNC:19344"
/translation="MSGGGGGGGSAPSRFADYFVICGLDTETGLEPDELSALCQYIQA
SKARDGASPFISSTTEGENFEQTPLRRTFKSKVLARYPENVEWNPFDQDAVGMLCMPK
GLAFKTQADPREPQFHAFIITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAE
YDVLHAPPADDRDQSSMEDGEDTPVTKLQRFNSYDISRDTLYVSKCICLITPMSFMKA
CRSVLQQLHQAVTSPQPPPLPLESYIYNVLYEVPLPPPGRSLKFSGVYGPIICQRPST
NELPLFDFPVKEVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFP
FQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDIDNHFI
ELPEDLPQFPNKLEFVQEVSEILMAFGIPPEGNLHCSESASKLKRLRASELVSDKRNG
NIAGSPLHSYELLKENETIARLQALVKRTGVSLEKLEVREDPSSNKDLKVQCDEEELR
IYQLNIQIREVFANRFTQMFADYEVFVIQPSQDKESWFTNREQMQNFDKASFLSDQPE
PYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLNVRTPTLRTS
MYQKCTTVDEAEKAIELRLAKIDHTAIHPHLLDMKIGQGKYEPGFFPKLQSDVLSTGP
ASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYIQEARTMGSTIRQPKLSNLSP
SVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCD
LLERIWSHGLQVKQGKSALWSHLLHYQDNRQRKLTSGSLSTSGILLDSERRKSDASSL
MPPLRISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKL
YKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFT
ANPWICISGELGETQIMQIPRNVLEMTFECQNLGKLTTVQIGHDNSGLYAKWLVEYVM
VRNEITGHTYKFPCGRWLGKGMDDGSLERILVGELLTSQPEVDERPCRTPPLQQSPSV
IRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKERGSLTLLLCGECGLVSA
LEQAFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEKNEVVPEENWHTRARNFCRFVTA
INNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLVNS
LIRVLQTLQEFNITLETSLVKGIDI"
BASE COUNT 1246 a 1169 c 1182 g 1185 t
ORIGIN
1 gcagcggcgg cggcgcggag gggaaggctc cgcactgccc ggccggtctc ggccccggcg
61 ccatgagtgg cggcggcggc ggagggggct cggcgcccag tcgcttcgcc gactactttg
121 tcatctgcgg actggacacg gagaccgggc tggagccgga cgagctgtcg gcattatgcc
181 agtacataca ggcttctaaa gccagggatg gtgccagccc tttcatttca agtacgactg
241 aaggagaaaa ttttgagcag acaccattga gaagaacatt caaatctaag gtccttgcac
301 gatatcctga gaacgtagaa tggaatccct ttgaccaaga tgcagtagga atgctatgta
361 tgccgaaagg gctggcattc aagacccagg ctgatcccag ggagccccaa ttccatgcct
421 ttattatcac aagggaggat ggctctcgga catttgggtt tgccctcaca ttttatgaag
481 aggtgactag caagcagatc tgcagtgcaa tgcagaccct ctaccacatg cacaatgctg
541 agtatgatgt cctacatgct ccccctgctg atgacagaga ccagagcagc atggaggatg
601 gtgaagacac tcctgtgacc aaactgcagc gcttcaactc ctatgacatt agccgggaca
661 ctctctacgt ctctaagtgc atctgcctca tcacacccat gtctttcatg aaggcatgtc
721 ggagcgtgct gcagcaactc caccaggcag tcacttcacc tcagccccct ccactgcccc
781 ttgagagcta catatacaac gtactctacg aggtgccgct cccacctcct ggccggtcct
841 tgaagttttc tggggtctat gggccaataa tctgccagag accaagtacc aatgagcttc
901 ccctatttga ctttcctgtc aaagaggttt ttgaactgct cggggtggag aatgtgtttc
961 agctttttac ttgtgccctt ctggagtttc aaatcctgct ctactcacag cattaccaga
1021 gactgatgac tgtggcggag acgattacag ctctcatgtt tcctttccag tggcagcatg
1081 tctatgtccc tattctccca gcttctctcc tgcatttctt agatgctcct gttccatacc
1141 tgatgggttt gcattccaat ggcctggatg accggtcaaa gctggagctg cctcaagagg
1201 ctaacctctg ctttgtggac attgacaacc acttcattga gttgccagag gacttgccac
1261 agttccccaa caaattggag tttgtccagg aagtctctga gattctcatg gcatttggaa
1321 ttccccctga agggaatctt cattgcagtg agagtgcctc caagctgaag aggctgcggg
1381 cctctgagct tgtctcggac aagaggaatg ggaacattgc tggctcccct ttgcattcct
1441 acgagcttct taaggagaat gaaactattg cccggctgca agccttggtc aagagaactg
1501 gggtgagcct ggaaaagttg gaagtgcgtg aagaccccag cagcaataag gatctcaaag
1561 ttcagtgtga tgaagaagaa ctcaggattt accagctaaa cattcagatc cgggaagttt
1621 ttgcaaatcg tttcactcag atgtttgcag attatgaggt gtttgtcatc caacccagcc
1681 aggataagga atcctggttt accaacaggg agcaaatgca aaactttgat aaagcatctt
1741 ttctgtcaga tcagcctgag ccctacctgc ccttcctctc aagattcctg gagacccaga
1801 tgtttgcatc tttcattgac aacaaaataa tgtgtcatga tgatgatgat aaagaccctg
1861 tactccgggt atttgattcc cgagttgaca agatcaggct gttgaatgtt cggacaccta
1921 ctctccgtac atccatgtac cagaagtgta ccactgtgga tgaagcagag aaagcaattg
1981 agctgcgtct ggcaaaaatt gaccatactg caattcaccc acatttactt gacatgaaga
2041 ttggacaagg gaaatatgag ccgggcttct tccctaagct gcagtctgat gtactttcca
2101 ctgggccagc cagcaacaag tggacgaaaa ggaatgcccc tgcccagtgg aggcggaaag
2161 atcggcagaa gcagcacaca gaacacctgc gtttagataa tgaccagagg gagaagtaca
2221 tccaggaagc caggactatg ggcagcacta tccgccagcc caaactgtcc aacctctctc
2281 catcagtgat tgcccagacc aattggaagt ttgtagaggg cctgctgaag gaatgccgca
2341 ataagaccaa gaggatgctg gtggaaaaga tgggccgaga agctgtggag ctagggcatg
2401 gggaggtgaa catcacaggg gtggaagaga acaccctgat tgccagcctt tgtgatctcc
2461 tggaaaggat ctggagtcat ggactacaag tgaaacaggg gaaatcagcc ttatggtccc
2521 acctgttaca ttatcaggac aaccggcaga gaaaactcac atcaggaagc ctcagtacct
2581 caggaatact tcttgattca gaacgtagga agtctgatgc cagctcactc atgcctcccc
2641 tgaggatctc cctgattcag gatatgaggc acatccagaa catcggggaa atcaagactg
2701 atgtgggaaa ggccagagca tgggtgcgac tgtccatgga aaaaaagtta ctttccagac
2761 acctgaagca gctcctctca gaccatgagc tcaccaaaaa gttatataag cgctatgcct
2821 tcctgcgctg tgatgacgag aaggagcagt tcctctatca cctcctgtct ttcaatgccg
2881 tcgattactt ttgcttcacc aatgtcttca caactatcct gatcccgtac cacattctga
2941 tcgtaccaag caagaagctg gggggctcca tgttcactgc caacccatgg atctgtatat
3001 caggagaatt gggtgagaca cagatcatgc agattcccag gaatgtgcta gagatgacct
3061 tcgagtgcca gaacttgggg aagcttacta ctgtccagat tggccatgat aactctgggc
3121 tgtatgccaa atggctggtg gagtatgtga tggtcaggaa tgagatcaca ggacatacct
3181 acaagttccc gtgtggccgg tggttaggga agggcatgga tgatggaagc ctggagcgga
3241 tcctagttgg ggagctgctc acatcccagc ctgaggtgga tgagaggcca tgccggaccc
3301 cgccgctgca gcagtccccc agtgtcatcc ggaggcttgt taccatctca cccaacaaca
3361 agcccaagct gaacactggg cagatccagg agtccatcgg ggaggcagtc aatggcattg
3421 tgaagcactt ccataagcct gagaaagagc gaggcagtct gacgctgttg ctctgtggag
3481 agtgtggcct tgtctcggcc ttggaacagg ctttccagca tggatttaaa tcgccccggc
3541 tcttcaaaaa tgtcttcatt tgggatttcc tggaaaaagc acaaacctat tatgagacat
3601 tagagaagaa tgaagtagtc cctgaggaaa actggcatac aagagcccgg aacttctgcc
3661 gatttgtcac tgcaatcaac aatactcccc ggaacatcgg caaggatggc aagtttcaga
3721 tgctggtgtg cttgggagcc agagatcacc tcctacacca ctggattgcc ctgctggctg
3781 actgccccat cactgcacac atgtatgagg atgtggcact gatcaaagac catacacttg
3841 tcaattcctt gattcgtgtg ctgcagacat tgcaggagtt caacatcacg ctggagacgt
3901 cccttgtcaa gggcatcgac atctgacctc ccagcaccag ccagcagcag gactgagaaa
3961 gactcaccct gcagctctga ccttttttcc caaagggact taagcgattg tgcaggagta
4021 ggagacaaaa tgtacactca ctgtaaaaag aaaactagag gatttttgga ataaataatc
4081 tattttagag tttatttgct gatttgcttt ttacacactt tcatgtgaaa gagtgatagg
4141 gagagggagc gaggctggtg ccgcttattt tgaagctggt gccctccctc gccgtggcca
4201 catgctggaa gcctgaggcc tccctggact gagcctgtgg cactgcgtgc gggacagtta
4261 tgtttccttg ccccgtcgca ttaatgaggc ccttccacat catttttaaa ctaatgtttt
4321 tctatattaa cattattatg gatatttggc tttcataggc cacacacagg tgtgctgcgc
4381 gggaagcccc atgctccaat caaagggatt tttagtagtg cctctaagca agcaccgatg
4441 agtcagtccc acgtattttc ttttttgtca gtattgtttg ggaaggagac atgccgggat
4501 gtgtcatcgt gccaaatacc acatttcctg ttggcacagt ttcacagaag taaacataag
4561 catgttttaa caggtttttc ttttcttttt tcttttttaa aatgttttat ttatttaacc
4621 tgccattgtg tgtttttaag tattttcttt ttttaaggaa aggaaaagct tgtcacaatc
4681 taactggcta tgttattatt attaaattta tgttttgcaa cttagaaacc agctacagta
4741 tggcccactt aataaaacac ctgaaacaaa aaaaaaaaaa aa
//