LOCUS BC071570 4723 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens protein tyrosine phosphatase, receptor type, N
polypeptide 2, mRNA (cDNA clone MGC:87154 IMAGE:4375815), complete
cds.
ACCESSION BC071570
VERSION BC071570.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4723)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4723)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 167 Row: b Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 19743910
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..4723
/db_xref="H-InvDB:HIT000264399"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87154 IMAGE:4375815"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4723
/gene="PTPRN2"
/gene_synonym="IA-2beta"
/gene_synonym="IAR"
/gene_synonym="ICAAR"
/gene_synonym="PTPRP"
/db_xref="GeneID:5799"
/db_xref="HGNC:HGNC:9677"
/db_xref="MIM:601698"
CDS 120..2021
/gene="PTPRN2"
/gene_synonym="IA-2beta"
/gene_synonym="IAR"
/gene_synonym="ICAAR"
/gene_synonym="PTPRP"
/codon_start=1
/product="PTPRN2 protein"
/protein_id="AAH71570.1"
/db_xref="GeneID:5799"
/db_xref="HGNC:HGNC:9677"
/db_xref="MIM:601698"
/translation="MGPPLPLLLLLLLLLPPRVLPAAPSSVPRGRQLPGRLGCLLEEG
LCGASEACVNGFTWQDDYTQYVMDQELADLPKTYLRRPEASSPARPSKHSVGSERRYS
REGGAALANALRRHLPFLEALSQAPASDVLARTHTAQDRPPAEGDDRFSESILTYVAH
TSALTYPPGPRTQLREDLLPRTLGQLQPDELSPKVDSGVDRHHLMAALSAYAAQRPPA
PPGEGSLEPQYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDL
QRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVARGSPGRAALGESGEQADGPKATLR
GDSFPDDGVQDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALTFARPLDMERKKSEH
PESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSLP
AGAQEALSDGLQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVEDVARLLQVPSSAFAD
VEVLGPAVTFKVSANVQNVTTEDVEKATVDNKDKLEETSGLKILQTGVGSKSKLKFLP
PQAEQEDSTKFIALTLVSLACILGVLLASGLIYCLRHSSQHRLKEKLSGLGGDPGADA
TAAYQELCR"
BASE COUNT 1062 a 1417 c 1342 g 902 t
ORIGIN
1 gagcgcgaga ggcgcggcgg gaggagccgg cggcgcgcgc ctccctgggc ccggactcgg
61 ccgcctcccg ccgcctcccg cgcggccatg gactgagcgc cgccggccag gccgcgggga
121 tggggccgcc gctcccgctg ctgctgctgc tactgctgct gctgccgcca cgcgtcctgc
181 ctgccgcccc ttcgtccgtc ccccgcggcc ggcagctccc ggggcgtctg ggctgcctgc
241 tcgaggaggg cctctgcgga gcgtccgagg cctgtgtgaa cggtttcacg tggcaggatg
301 actatactca gtatgtgatg gaccaggaac ttgcagacct cccgaaaacc tacctgaggc
361 gtcctgaagc atccagccca gccaggccct caaaacacag cgttggcagc gagaggaggt
421 acagtcggga gggcggtgct gccctggcca acgccctccg acgccacctg cccttcctgg
481 aggccctgtc ccaggcccca gcctcagacg tgctcgccag gacccatacg gcgcaggaca
541 gaccccccgc tgagggtgat gaccgcttct ccgagagcat cctgacctat gtggcccaca
601 cgtctgcgct gacctaccct cccgggcccc ggacccagct ccgcgaggac ctcctgccgc
661 ggaccctcgg ccagctccag ccagatgagc tcagccctaa ggtggacagt ggtgtggaca
721 gacaccatct gatggcggcc ctcagtgcct atgctgccca gaggccccca gctccccccg
781 gggagggcag cctggagcca cagtaccttc tgcgtgcacc ctcaagaatg cccaggcctt
841 tgctggcacc agccgccccc cagaagtggc cttcacctct gggagattcc gaagacccct
901 ctagcacagg cgatggagca cggattcata ccctcctgaa ggacctgcag aggcagccgg
961 ctgaggtgag gggcctgagt ggcctggagc tggacggcat ggctgagctg atggctggcc
1021 tgatgcaagg cgtggaccat ggagtagctc gaggcagccc tgggagagcg gccctgggag
1081 agtctggaga acaggcggat ggccccaagg ccaccctccg tggagacagc tttccagatg
1141 acggagtgca ggacgacgat gatagacttt accaagaggt ccatcgtctg agtgccacac
1201 tcgggggcct cctgcaggac cacgggtctc gactcttacc tggagccctc acctttgcaa
1261 ggcccctcga catggagagg aagaagtccg agcaccctga gtcttccctg tcttcagaag
1321 aggagactgc cggagtggag aacgtcaaga gccagacgta ttccaaagat ctgctggggc
1381 agcagccgca ttcggagccc ggggccgctg cgtttgggga gctccaaaac cagatgcctg
1441 ggccctcgaa ggaggagcag agccttccag cgggtgctca ggaggccctc agcgacggcc
1501 tgcaattgga ggtccagcct tccgaggaag aggcgcgggg ctacatcgtg acagacagag
1561 accccctgcg ccccgaggaa ggaaggcggc tggtggagga cgtcgcccgc ctcctgcagg
1621 tgcccagcag cgcgttcgct gacgtggagg ttctcggacc agcagtgacc ttcaaagtga
1681 gcgccaatgt ccaaaacgtg accactgagg atgtggagaa ggccacagtt gacaacaaag
1741 acaaactgga ggaaacctct ggactgaaaa ttcttcaaac cggagtcggg tcgaaaagca
1801 aactcaagtt cctgcctcct caggcggagc aagaagactc caccaagttc atcgcgctca
1861 ccctggtctc cctcgcctgc atcctgggcg tcctcctggc ctctggcctc atctactgcc
1921 tccgccatag ctctcagcac aggctgaagg agaagctctc gggactaggg ggcgacccag
1981 gtgcagatgc cactgccgcc taccaggagc tgtgccgcta gcgtatggcc acgcggccac
2041 cagaccgacc tgagggcccg cacacgtcac gcatcagcag cgtctcatcc cagttcagcg
2101 acgggccgat ccccagcccc tccgcacgca gcagcgcctc atcctggtcc gaggagcctg
2161 tgcagtccaa catggacatc tccaccggcc acatgatcct gtcctacatg gaggaccacc
2221 tgaagaacaa gaaccggctg gagaaggagt gggaagcgct gtgcgcctac caggcggagc
2281 ccaacagctc gttcgtggcc cagagggagg agaacgtgcc caagaaccgc tccccggctg
2341 tgctgaccta tgaccactcc cgggtcctgc tgaaggcgga gaacagccac agccactcag
2401 actacatcaa cgctagccct atcatggatc acgacccgag gaaccccgcg tacatcgcca
2461 cccagggacc gctgcccgcc accgtggctg acttttggca gatggtgtgg gagagcggct
2521 gcgtggtgat cgtcatgctg acacccctcg cggagaacgg cgtccggcag tgctaccact
2581 actggccgga tgaaggctcc aatctctacc acatctatga ggtgaacctg gtctccgagc
2641 acatctggtg tgaggacttc ctggtgagga gcttctatct gaagaacctg cagaccaacg
2701 agacgcgcac cgtgacgcag ttccacttcc tgagttggta tgaccgagga gtcccttcct
2761 cctcaaggtc cctcctggac ttccgcagaa aagtaaacaa gtgctacagg ggccgttctt
2821 gtccaataat tgttcattgc agtgacggtg caggccggag cggcacctac gtcctgatcg
2881 acatggttct caacaagatg gccaaaggtg ctaaagagat tgatatcgca gcgaccctgg
2941 agcacttgag ggaccggaga cccggcatgg tccagacgaa ggagcagttt gagttcgcgc
3001 tgacagccgt ggctgaggag gtgaacgcca tcctcaaggc ccttccccag tgagcggcag
3061 cctcaggggc ctcaggggag cccccacccc acggatgttg tcaggaatca tgatctgact
3121 ttaattgtgt gtcttctatt ataactgcat agtaataggg cccttagctc tcccgtagtc
3181 agcgcagttt agcagttaaa agtgtatttt tgtttaatca aacaataata aagagagatt
3241 tgtggaaaaa tccagttacg ggtggagggg aataggttca tcaattttca cttgcttaaa
3301 aaaaatactt tttcttaaag cacccgttca ccttcttggt tgaagttgtg ttaacaatgc
3361 agtagccagc acgttcgagg cggtttccag gaagagtgtg cttgtcatct gccactttcg
3421 ggagggtgga tccactgtgc aggagtggcc ggggaagctg gcagcactca gtgaggccgc
3481 ccggcacaca aggcacgttt ggcatttctc tttgagagag tttatcattg ggagaagccg
3541 cggggacaga actgaacgtc ctgcagcttc ggggcaagtg agacaatcac agctcctcgc
3601 tgcgtctcca tcaacactgc gccgggtacc atggacggcc ccgtcagcca cacctgtcag
3661 cccaagcaga gtgattcagg ggctccccgg gggcagacac ctgtgcaccc catgagtagt
3721 gcccacttga ggctggcact cccctgacct cacctttgca aagttacaga tgcaccccaa
3781 cattgagatg tgtttttaat gttaaaatat tgatttctac gttatgaaaa cagatgcccc
3841 catgaatgct tacctgtgag ataaccacaa ccaggaagaa caaatctggg cattgagcaa
3901 gctatgaggg tccccgggag cacacgaacc ctgccaggcc cccgctggct cctccaggca
3961 cgtcccggac ctgtggggcc ccagagaggg gacatttccc tcctgggaga gaaggagatc
4021 agggcaactc ggagagggct gcgagcattt ccctcccggg agagatcagg gcgacctgca
4081 cgcactgcgt agagcctgga agggaagtga gaaaccagcc gaccggccct gcccctcttc
4141 ccgggatcac ttaatgaacc acgtgttttg acatcatgta aacctaagca cgtagagatg
4201 attcggattt gacaaaataa catttgagta tccgattcgc catcaccccc taccccagaa
4261 ataggacaat tcacttcatt gaccaggatg atcacatgga aggcggcgca gaggcagctg
4321 tgtgggctgc agatttcctg tgtggggttc agcgtagaaa acgcacctcc atcccgccct
4381 tcccacagca ttcctccatc ttagatagat ggtactctcc aaaggcccta ccagagggaa
4441 cacggcctac tgagcggaca gaatgatgcc aaaatattgc ttatgtctct acatggtatt
4501 gtaatgaata tctgctttaa tatagctatc atttcttttc caaaattact tctctctatc
4561 tggaatttaa ttaatcgaaa tgaatttatc tgaatatagg aagcatatgc ctacttgtaa
4621 tttctaactc cttatgtttg aagagaaacc tccggtgtga gatatacaaa tatatttaat
4681 tgtgtcatat taaacttctg atttcacaaa aaaaaaaaaa aaa
//