LOCUS BC070266 2494 bp mRNA linear HUM 21-JUL-2006
DEFINITION Homo sapiens cytotoxic and regulatory T cell molecule, mRNA (cDNA
clone MGC:88255 IMAGE:30418882), complete cds.
ACCESSION BC070266
VERSION BC070266.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2494)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2494)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-MAY-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Narayan Bhat
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 57 Row: p Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 51593097.
FEATURES Location/Qualifiers
source 1..2494
/db_xref="H-InvDB:HIT000264224"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:88255 IMAGE:30418882"
/tissue_type="Blood, peripheral blood mononuclear cells
(PBMC) cytoplasmic poly A RNA is pooled sample from 3 and
6 hr after stimulation with PMA and Ionomycin. These
reagents are used to activate T- cells that results in
lymphokine and cytokine production."
/clone_lib="NIH_MGC_191"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..2494
/gene="CRTAM"
/db_xref="GeneID:56253"
/db_xref="HGNC:HGNC:24313"
CDS 50..1231
/gene="CRTAM"
/codon_start=1
/product="cytotoxic and regulatory T cell molecule"
/protein_id="AAH70266.1"
/db_xref="GeneID:56253"
/db_xref="HGNC:HGNC:24313"
/translation="MWWRVLSLLAWFPLQEASLTNHTETITVEEGQTLTLKCVTSLRK
NSSLQWLTPSGFTIFLNEYPVLKNSKYQLLHHSANQLSITVPNVTLQDEGVYKCLHYS
DSVSTKEVKVIVLATPFKPILEASVIRKQNGEEHVVLMCSTMRSKPPPQITWLLGNSM
EVSGGTLHEFETDGKKCNTTSTLIIHTYGKNSTVDCIIRHRGLQGRKLVAPFRFEDLV
TDEETASDALERNSLSSQDPQQPTSTVSVTEDSSTSEIDKEEKEQTTQDPDLTTEANP
QYLGLARKKSGILLLTLVSFLIFILFIIVQLFIMKLRKTHVIWKKENEVSEHTLESYR
SRSNNEETSSEEKNGQSSHPMRCMNYITKLYSEGKTKRKENVQHSKLEEKHIQVPESI
V"
BASE COUNT 813 a 526 c 550 g 605 t
ORIGIN
1 tcagaatcta gaggaagttg acaaaggtgc cacagcagca cagcacagta tgtggtggag
61 agttctcagc ttgctggcat ggttcccctt gcaagaggcc tctctgacta accacacaga
121 aaccatcacc gtggaggaag gccagacgct cactctaaag tgtgtcactt ctctgaggaa
181 gaactcctcc ctccagtggc tgaccccctc agggttcacc atttttttaa atgagtatcc
241 tgttttaaaa aattccaaat accagcttct tcatcactcg gccaatcagc tctccatcac
301 tgtgcctaac gtaaccctgc aagatgaagg cgtgtacaag tgcttacatt acagcgactc
361 tgtaagcaca aaggaagtga aagtgattgt gctggcaact cctttcaagc caatcctgga
421 agcttcagtt atcagaaagc aaaatggaga agaacatgtt gtactcatgt gctccaccat
481 gagaagcaag ccccctccgc agataacctg gctacttggg aatagcatgg aagtgtccgg
541 tggaacgctc catgaatttg aaactgatgg gaagaaatgt aatactacca gcactctcat
601 aatccacact tatggcaaaa attcaacggt ggactgcatt atccgacaca gaggcctgca
661 agggagaaaa ctagtagcac ccttccggtt tgaagatttg gttactgatg aagagacagc
721 ttcagatgct ctggagagaa actctctatc ctctcaagac ccacagcagc ccaccagtac
781 tgtctcagta acggaagatt ctagtacatc ggagattgac aaggaagaga aagaacaaac
841 cactcaagat cctgacttga ccaccgaagc aaatcctcag tatttaggac tggcaagaaa
901 gaaaagtggc atcctgctgc tcacgctggt gtccttcctc attttcatac tcttcatcat
961 agtccagctc ttcatcatga agctgaggaa aacacatgtg atatggaaga aagaaaacga
1021 agtttcagaa cacacactag aaagttacag atcaaggtca aataatgaag aaacatcatc
1081 tgaagagaaa aatggccaat cttcccaccc tatgcgttgc atgaactaca tcacaaagtt
1141 gtactcagaa ggaaaaacaa agaggaagga aaatgtacaa cattcaaaat tagaagaaaa
1201 gcacatccaa gtaccagaga gtattgtgta gtgctctctg caatggaaca tgtgatttca
1261 gggttgccgc agtgtcacct cagtggacca gcctggggga aggagcttaa ttgctgagac
1321 attaataatg acctcttagt gcaatgcaag atggtgtcct cggataatga tctgccccgg
1381 agctagggca gcaacatgag gaccaaacca tgcacataaa gcttgtagtt taaaaaagaa
1441 aagcaaaaaa ataattatgc ctgacactac ttcagagcag gaggattcta cgaagccttg
1501 gggatcaggg tcagtgtgag cagctaacat cctacctcaa atggaacagg attttttgat
1561 gctttgctct aatggaactg ttttaaaaat ttttttttct ttttaatatt ttcttctggt
1621 cacaaaataa agaaatttgg gatgcaaagt acctaaagat ctctgatcct aagaagttac
1681 ttctggccag gcgcggtggc tcatgcctgt aatcctagca ctttgggagg ctgaggtagg
1741 cagatcactt gaggtcagga gttggagacc agcctggcca acatagtgaa accccgtctc
1801 tactaaaaat gcaaaaatta gccaggcgta gtggtgcgca cctgtagtct cagatacttg
1861 ggaggctgag ggtggagaat cgcttgaacc tgggaggtgg agattgcagt gagtcaagat
1921 ctcaccactg cactccagcc tgggcgacag agggagactc tgtctcaaaa aaaaagaagt
1981 tacttccaag acagactttt aagatgtaac cagcacaaag caatgtcagg gaggagtgat
2041 acatgacaat aaatgagtca gatgagcaag aaggccccag aacccatgcc ccaaggcaca
2101 aagaggagct cagggtaggc ccaaagattc gaattcctta gattactaaa tcacatgagc
2161 ggaccttgtc tgtcagataa gatttttacc tggaaattcc atgaccaata catgtgcaaa
2221 agaaaatgat gggttgaatt tactgattat tgacctaatg gatggctttt taaaatgttt
2281 taataaaaag cagaatagat gtttgttttt ctagtggtta taccaagtta tacttcctgt
2341 tttcacgtgt gaaagtaaca tgggacatgc ctttcttttc cgatcagttt atttaagcta
2401 tacagcaaac tttggcattt atgtggagca tttctcattg ttggaatctg aataaaccaa
2461 taacaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//