LOCUS BC070082 3953 bp mRNA linear HUM 09-JUN-2008
DEFINITION Homo sapiens phosphoinositide-3-kinase, regulatory subunit 2
(beta), mRNA (cDNA clone MGC:87406 IMAGE:30343107), complete cds.
ACCESSION BC070082
VERSION BC070082.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3953)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3953)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-MAY-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Stefan Hansson
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 168 Row: m Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 48976048.
FEATURES Location/Qualifiers
source 1..3953
/db_xref="H-InvDB:HIT000264040"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87406 IMAGE:30343107"
/tissue_type="Placenta, normal"
/clone_lib="NIH_MGC_147"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3953
/gene="PIK3R2"
/gene_synonym="p85"
/gene_synonym="p85-BETA"
/gene_synonym="P85B"
/db_xref="GeneID:5296"
/db_xref="HGNC:HGNC:8980"
/db_xref="MIM:603157"
CDS 513..2699
/gene="PIK3R2"
/gene_synonym="p85"
/gene_synonym="p85-BETA"
/gene_synonym="P85B"
/codon_start=1
/product="phosphoinositide-3-kinase, regulatory subunit 2
(beta)"
/protein_id="AAH70082.1"
/db_xref="GeneID:5296"
/db_xref="HGNC:HGNC:8980"
/db_xref="MIM:603157"
/translation="MAGPEGFQYRALYPFRRERPEDLELLPGDVLVVSRAALQALGVA
EGGERCPQSVGWMPGLNERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPRD
GAPEPGLTLPDLPEQFSPPDVAPPLLVKLVEAIERTGLDSESHYRPELPAPRTDWSLS
DVDQWDTAALADGIKSFLLALPAPLVTPEASAEARRALREAAGPVGPALEPPTLPLHR
ALTLRFLLQHLGRVARRAPALGPAVRALGATFGPLLLRAPPPPSSPPPGGAPDGSEPS
PDFPALLVEKLLQEHLEEQEVAPPALPPKPPKAKPAPTVLANGGSPPSLQDAEWYWGD
ISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHRDGHYGFSEP
LTFCSVVDLINHYRHESLAQYNAKLDTRLLYPVSKYQQDQIVKEDSVEAVGAQLKVYH
QQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSKEYLER
FRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQQLRAQASDNREIDKRMNSLKPD
LMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNETEDQYALMEDEDDLPHHEERTWYV
GKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEP
YNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPPAAR"
BASE COUNT 761 a 1339 c 1179 g 674 t
ORIGIN
1 ggctgcggcg acggtggccg cggtggagcc acggggcggg cttggcttgg tgtgacggcg
61 gctgcggcgg cggtggcggc cgcgaccagg tcggcgtcct cagctggccg agcatggtgg
121 cagcctgcac ccttggctcc cttgtctggt gcagccagca gagccgccag ccttgggcgc
181 ccatggccct ccgtgtgagg gcgtgagcgg cctgccccag cctcacctgc tgatggagga
241 ctcaatggcc cagtgacctg acaccacacc accaactccc tcccaccagc tgacgaatgg
301 tggacccagt gacgagtggc ccttgtaagg gtcatggaat aatttgaagc gaggcatgag
361 cggcccctgt ggtcgcctgt gactgctgga gatagaggtc ccagcacccc aagccaaccc
421 agcggaccct cccagccctg cttcaaccaa tggggccagt ggggctccaa gcagccacct
481 aaccatccag accccacccc actcacgcgg ccatggcggg ccctgagggc ttccagtacc
541 gcgctctgta cccgttccgc cgggagcggc cggaggacct ggagctgctg cccggcgacg
601 tgctggtagt gagccgggcg gccttgcagg cgctgggcgt ggccgagggt ggcgagcgct
661 gcccacagag cgtgggctgg atgcccggcc tcaacgagcg cacacggcag cgaggtgact
721 tccctggcac ctatgtggag ttcctggggc ccgtggccct ggcccggccc ggccctcgcc
781 cacggggccc ccgcccactg cccgccaggc cccgtgatgg ggcccctgag ccaggcctca
841 cactccccga cttgcccgag cagttctccc cacctgatgt ggctccccct cttctggtga
901 agcttgtgga ggccattgaa aggacagggc tggacagcga atctcactac cgcccggagc
961 tgcccgcacc gcgtacagac tggtccctga gcgacgtgga tcagtgggac acggcagccc
1021 tggctgacgg cattaagagc ttcctgctgg cactgcccgc gccgctcgtg acccccgagg
1081 cctcggccga ggcgcgccgg gccctgcggg aggccgcggg gcccgtgggg ccggcgctgg
1141 agccaccgac gctgccgctg caccgcgcgc tcacgctgcg cttcctgctc cagcacctgg
1201 gccgcgtggc ccgccgcgcc ccggccctgg gtcccgcggt ccgggccctg ggcgccacct
1261 ttgggccgct gctgctgcgc gcgccgccgc cgccgtcctc gccgccgcca gggggcgctc
1321 ccgacgggag tgagcccagc cctgacttcc cggcgctgct ggtggagaag ctgcttcagg
1381 aacacttgga agagcaggag gttgcgcccc cagcgctgcc gcctaaaccc cccaaggcaa
1441 agccggcccc cacagtcctg gccaatggag ggagcccacc ctccctgcag gatgctgagt
1501 ggtactgggg ggacatttca agggaggagg tgaacgagaa actccgggac actcccgatg
1561 gcaccttcct agtccgagat gcttctagca agatccaggg cgagtacacg ctgaccctca
1621 ggaaaggcgg gaacaataag ctgatcaagg tcttccaccg agatgggcac tatggcttct
1681 cagagccact caccttctgc tccgttgtgg acctcatcaa tcactaccgc cacgagtctc
1741 tggcccagta caatgccaag ctggacacac ggctcctcta ccctgtgtcc aaataccagc
1801 aggaccagat tgtcaaggag gacagcgtgg aggcagtggg cgcccagctt aaggtctatc
1861 accagcagta ccaggacaag agccgcgagt atgaccagct ttatgaagag tacacacgga
1921 cctcccagga gctgcagatg aagcgtactg caattgaggc cttcaatgag actatcaaga
1981 tctttgaaga gcagggccag actcaagaga aatgcagcaa ggaatacctg gagcgcttcc
2041 ggcgtgaggg caacgagaaa gagatgcaaa ggatcctgct gaactccgag cggctcaagt
2101 cccgcattgc cgagatccat gagagccgca cgaagctgga gcagcagctg cgggcccagg
2161 cctcggacaa cagagagatc gacaagcgca tgaacagcct caagccggac ctcatgcagc
2221 tgcgcaagat ccgagaccag tacctcgtgt ggctcaccca gaaaggcgcc cggcagaaga
2281 aaatcaacga gtggctgggg attaaaaatg agactgagga ccagtacgca ctcatggagg
2341 acgaggacga tctcccgcac cacgaggaac gcacttggta cgtgggcaag atcaaccgca
2401 cgcaggcaga ggagatgctg agtggcaagc gggatggcac cttcctcatc cgcgagagca
2461 gccagcgggg ctgctacgcc tgctccgtgg tagtggacgg cgacaccaag cactgcgtca
2521 tctaccgcac ggccaccggc ttcggcttcg cggagcccta caacctgtac gggtcgctga
2581 aggagctggt gctgcactac cagcacgcct cgctggtgca gcacaacgac gcgctcaccg
2641 tcaccctggc gcacccagtg cgcgccccgg gccccggccc gccgcctgcc gcccgctgag
2701 caccgaggac ccgccccaag cagagccgcc cctgggcccg tctgcgccgg aggctgcggc
2761 ggcgggagcc acggaccaga ccagccacat ccaggggtcc tcatttctcc ggctctggct
2821 cttgtttggg gttctctcac cctctttctc tttccttccc tcccccattc tccagatctc
2881 cctctgtctc cttttctctg tctttcttgg cccctgtctc tctccatgtt gggggtccta
2941 actcccccac cccatatcta cgtgtcctcc gggcattgcc ctctccatgg ctctggtcac
3001 cctgaccctc tgccctgccc accgcaggtc ccccggggtc ccggaagccc cttctggctg
3061 cacctgccat gtttacagag ggcccctggg ctgcgcggcc ccagcctggg caccctgatt
3121 tttaagccat agacctgggg tcagggcagg aaggaacttc actctgctgc ttccgagaac
3181 ctcggccgtg acattcgggg ccgggcggga cccgccccac agactccaac ttcccctcca
3241 aaccccgaag tgaaacccgc caccgggtta cccccacaag ggggccgctg cgagaagttc
3301 acccaccccc gaaaaaataa ttaaactcgc aggccaggca cggtggctca tgcctgtaat
3361 cccagcactt tgggaggcca agacgggcgg atcttttgag gtcgggagtt ggaggccagc
3421 ctggccaaaa tggcaaaacc ccgcatctac taaaatacaa aaattagccg ggcgtggtgg
3481 cggccgcctg taatcccagc tacttgggag gctgaggcgt gagaatctct tgaacccagg
3541 agatggaggt tgcagtgagc agagatcgtg ccactgcact ccagcctggg taacagaggg
3601 agactcctcc gtctcaaaaa aataaataaa taaacttgtg agctggcccc aacccctcct
3661 aggaatcaca gctccccgta ctggtgccgc cgcagtggcc aagttgcgac actgcccacg
3721 gcccctccct ctgatgcaga ttcagggctt ctcttcgatc atgttgggtt ttgattctgt
3781 ttttccttga ctgcaaaacc ctctttcctc tcctcttttg ggacaagagc cctggttttc
3841 tacgctgccc ttggccacca cactgcctgc cccacgagct gggaggcagg ttttgtacgg
3901 tacgttgtta ttgatatgat ataaaacatc aaacgtcgaa aaaaaaaaaa aaa
//