LOCUS BC070077 4398 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens serine/threonine kinase 10, mRNA (cDNA clone MGC:87394
IMAGE:5267449), complete cds.
ACCESSION BC070077
VERSION BC070077.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4398)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4398)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-MAY-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 167 Row: m Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 47271450.
FEATURES Location/Qualifiers
source 1..4398
/db_xref="H-InvDB:HIT000264035"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87394 IMAGE:5267449"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4398
/gene="STK10"
/gene_synonym="LOK"
/gene_synonym="PRO2729"
/db_xref="GeneID:6793"
/db_xref="HGNC:HGNC:11388"
/db_xref="MIM:603919"
CDS 215..3121
/gene="STK10"
/gene_synonym="LOK"
/gene_synonym="PRO2729"
/codon_start=1
/product="serine/threonine kinase 10"
/protein_id="AAH70077.1"
/db_xref="GeneID:6793"
/db_xref="HGNC:HGNC:11388"
/db_xref="MIM:603919"
/translation="MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGD
GAFGKVYKAKNKETGALVAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYH
DGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQEVCRQMLEALNFLHSKRIIHRDLKA
GNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKA
DIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALD
KNPETRPSAAQLLEHPFVSSITSNKALRELVAEAKAEVMEGIEDGRDEGEEEDAVDAA
STLENHTQNSSEVSPPSLNADKPLEESPSTPLAPSQSQDSVNEPCSQPSGDRSLQTTS
PPVVAPGNENGLAVPVPLRKSRPVSMDARIQVAQEKQVAEQGGDLSPAANRSQKASQS
RPNSSALETLGGEKLANGSLEPPAQAAPGPSKRDSDCSSLCTSESMDYGTNLSTDLSL
NKEMGSLSIKDPKLYKKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQEL
RELRLLQKEEHRNQTQLSNKHELQLEQMHKRFEQEINAKKKFFDTELENLERQQKQQV
EKMEQDHAVRRREEARRIRLEQDRDYTRFQEQLKLMKKEVKNEVEKLPRQQRKESMKQ
KMEEHTQKKQLLDRDFVAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRDRE
AALWEMEEHQLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVR
QQQEKARLPKIQRSEGKTRMAMYKKSLHINGGGSAAEQREKIKQFSQQEEKRQKSERL
QQQQKHENQMRDMLAQCESNMSELQQLQNEKCHLLVEHETQKLKALDESHNQNLKEWR
DKLRPRKKALEEDLNQKKREQEMFFKLSEEAECPNPSTPSKAAKFFPYSSADAS"
BASE COUNT 1063 a 1248 c 1312 g 775 t
ORIGIN
1 gcgggcacgc cgccgcctgc gcggttccgg gtgctcccgg cgcggcgctg cccagggcac
61 acttgaccga ggtcgggctg cggggaaagg cgggtctggg gagaaccccg agagacgcgg
121 cgtcctccaa ctcctcctcc ttctcctcgc ggccgccgaa gccacagccc gagcccgagc
181 ccgagcccga gccggcgcca ccgcgccccc ggccatggct tttgccaatt tccgccgcat
241 cctgcgcctg tctaccttcg agaagagaaa gtcccgcgaa tatgagcacg tccgccgcga
301 cctggacccc aacgaggtgt gggagatcgt gggcgagctg ggcgacggcg ccttcggcaa
361 ggtttacaag gccaagaata aggagacggg tgctttggtt gcggccaaag tcattgaaac
421 caagagtgag gaggagctgg aggactacat cgtggagatt gagatcctgg ccacctgcga
481 ccacccctac attgtgaagc tcctgggagc ctactatcac gacgggaagc tgtggatcat
541 gattgagttc tgtccagggg gagccgtgga cgccatcatg ctggagctgg acagaggcct
601 cacggagccc cagatacagg aggtttgccg ccagatgcta gaagccctca acttcctgca
661 cagcaagagg atcatccacc gagatctgaa agctggcaac gtgctgatga ccctcgaggg
721 agacatcagg ctggctgact ttggtgtgtc tgccaagaat ctgaagactc tacagaaacg
781 agattccttc atcggcacgc cttactggat ggcccccgag gtggtcatgt gtgagaccat
841 gaaagacacg ccctacgact acaaagccga catctggtcc ctgggcatca cgctgattga
901 gatggcccag atcgagccgc cacaccacga gctcaacccc atgcgggtcc tgctaaagat
961 cgccaagtca gaccctccca cgctgctcac gccctccaag tggtctgtag agttccgtga
1021 cttcctgaag atagccctgg ataagaaccc agaaacccga cccagtgccg cgcagctgct
1081 ggagcatccc ttcgtcagca gcatcaccag taacaaggct ctgcgggagc tggtggctga
1141 ggccaaggcc gaggtgatgg aagggatcga agacggccgg gatgaggggg aagaggagga
1201 cgccgtggat gccgcctcca ccctggagaa ccatactcag aactcctctg aggtgagtcc
1261 gccaagcctc aatgctgaca agcctctcga ggagtcacct tccaccccgc tggcacccag
1321 ccagtctcag gacagtgtga atgagccctg cagccagccc tctggggaca gatccctcca
1381 aaccaccagt cccccagtcg tggcccctgg aaatgagaac ggcctggcag tgcctgtgcc
1441 cctgcggaag tcccgacccg tgtcaatgga tgccagaatt caggtagccc aggagaagca
1501 agttgctgag cagggtgggg acctcagccc agcagccaac agatctcaaa aggccagcca
1561 gagccggccc aacagcagcg ccctggagac cttgggtggg gagaagctgg ccaatggcag
1621 cctggagcca cctgcccagg cagctccagg gccttccaag agggactcgg actgcagcag
1681 cctctgcacc tctgagagca tggactatgg taccaatctc tccactgacc tgtcgctgaa
1741 caaagagatg ggctctctgt ccatcaagga cccgaaactg tacaaaaaaa ccctcaagcg
1801 gacacgcaaa tttgtggtgg atggtgtgga ggtgagcatc accacctcca agatcatcag
1861 cgaagatgag aagaaggatg aggagatgag atttctcagg cgccaggaac tccgagagct
1921 tcggctgctc cagaaagaag agcatcggaa ccagacccag ctgagtaaca agcatgagct
1981 gcagctggag caaatgcata aacgttttga acaggaaatc aacgccaaga agaagttctt
2041 tgacacggaa ttagagaacc tggagcgtca gcaaaagcag caagtggaga agatggagca
2101 agaccatgcc gtgcgccgcc gggaggaggc caggcggatc cgcctggagc aggatcggga
2161 ctacaccagg ttccaagagc agctcaaact gatgaagaaa gaggtgaaga acgaggtgga
2221 gaagctcccc cgacagcagc ggaaggaaag catgaagcag aagatggagg agcacacgca
2281 gaaaaagcag cttcttgacc gggactttgt agccaagcag aaggaggacc tggagctggc
2341 catgaagagg ctcaccaccg acaacaggcg agagatctgt gacaaggagc gcgagtgcct
2401 catgaagaag caggagctcc ttcgagaccg ggaagcagcc ctgtgggaga tggaagagca
2461 ccagctgcag gagaggcacc agctggtgaa gcagcagctc aaagaccagt acttcctcca
2521 gcggcacgag ctgctgcgca agcatgagaa ggagcgggag cagatgcagc gctacaacca
2581 gcgcatgata gagcagctga aggtgcggca gcaacaggaa aaggcgcggc tgcccaagat
2641 ccagaggagt gagggcaaga cgcgcatggc catgtacaag aagagcctcc acatcaacgg
2701 cgggggcagc gcagctgagc agcgtgagaa gatcaagcag ttctcccagc aggaggagaa
2761 gaggcagaag tcggagcggc tgcagcaaca gcagaaacac gagaaccaga tgcgggacat
2821 gctggcgcag tgtgagagca acatgagcga gctgcagcag ctgcagaatg aaaagtgcca
2881 cctcctggta gagcacgaaa cccagaaact gaaggccctg gatgagagcc ataaccagaa
2941 cctgaaggaa tggcgggaca agcttcggcc gcgcaagaag gctctggaag aggatctgaa
3001 ccagaagaag cgggagcagg agatgttctt caagctgagc gaggaggcgg agtgcccaaa
3061 cccctccacc ccaagcaagg ctgccaagtt cttcccctac agttctgcgg atgcttctta
3121 acaaccgccc ggggctgtgg ctggcagctt ggtgggcccc agggccttct ccttcattct
3181 ctgtgaacat gtaactcagg accccttttc cctcttgcgt ctgtgccagc tcaaatccag
3241 cccctcgccc tgtgccaccc caactgtgcc tgatagacct gccccagcgt tcctgacttc
3301 ttgctggcct gtggagggtg aggtgtaatt atttgtcacc tgaacctaat gtatattctc
3361 cttgagcccc agatcccttc aagctggaag ggatggggct gttggtgggg tcagggtcca
3421 agaggaatgg gtgttctgtg gcctcgagtc ctctcctgtt tgcgaaaata ccagttttgc
3481 tctctgtggg acaaagcact gctgatgaag tccccgtggg ctcatccggg ctggaattct
3541 tggtttttca gccattccct gcagagtcac tcaatcatca agtccctcac agccatttct
3601 gttcccagag gagccaggcc tgcagctggc tgctcaggag atggcctcat tcctcctgtt
3661 ctcccagttt gctttccact taagacaaag ccttgtctat gtggggggcg gggaccgggg
3721 aaagagggag gctgaaatgt ttattctgct tctcccgtgt ttcatgccat ctcgcgtccc
3781 ccttcctgca catgggtgtg aatgcacaca catacgcgta cacacaggac ttggtctgct
3841 ggcctggcct cttctgccca ggtgggttgg aacacgtttg ctgcctgagc ctgtgccact
3901 gagcatgtta ggtggagcag ttggtgtggc acgtgcgggg tgttggcacc ggaggcatgg
3961 agaagcacag gctgtactgc caggctgcga tgcgtgctgg cccccgcaca ggctcctgtg
4021 tgcagggact gattcctcag cacacgaggc ttccacaacc cagtctgctc catagcactc
4081 tggcccaccc tgtctgcagg tgaaacagga gggctgtttg cctctgcccc atccccccga
4141 ctgtgttcag gagtcccacc ttgcatttca gacatgggct ggcagtctgt tggacttctc
4201 ttcaggaaga aaaagcatca gggggaaatg gaatgcccct gccccaggaa catggcagaa
4261 gcacaggttc tgtacctcag atggactcct gctgggcctt cggggtctca gttgacttcc
4321 cccagattct gattctacag ctgcagaatg tatataacgc aataaaagca aatgtttgaa
4381 ccaaaaaaaa aaaaaaaa
//