LOCUS BC070070 3609 bp mRNA linear HUM 09-JUN-2008
DEFINITION Homo sapiens discoidin domain receptor tyrosine kinase 1, mRNA
(cDNA clone MGC:87336 IMAGE:5262509), complete cds.
ACCESSION BC070070
VERSION BC070070.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3609)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3609)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-MAY-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 167 Row: j Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38327631.
FEATURES Location/Qualifiers
source 1..3609
/db_xref="H-InvDB:HIT000264028_07"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87336 IMAGE:5262509"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3609
/gene="DDR1"
/gene_synonym="CD167"
/gene_synonym="DDR"
/gene_synonym="MCK10"
/gene_synonym="PTK3"
/gene_synonym="RTK6"
/gene_synonym="TRKE"
/db_xref="GeneID:780"
/db_xref="HGNC:HGNC:2730"
/db_xref="MIM:600408"
CDS 105..2735
/gene="DDR1"
/gene_synonym="CD167"
/gene_synonym="DDR"
/gene_synonym="MCK10"
/gene_synonym="PTK3"
/gene_synonym="RTK6"
/gene_synonym="TRKE"
/codon_start=1
/product="DDR1 protein"
/protein_id="AAH70070.1"
/db_xref="GeneID:780"
/db_xref="HGNC:HGNC:2730"
/db_xref="MIM:600408"
/translation="MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPD
SDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGT
QGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMV
ARLVHFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGH
TVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDR
LRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAV
SVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPP
TNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKA
ERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSAYSG
DYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRV
DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDA
TKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLE
DKAAEGAPGDGQAAQGPTISYQMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN
FTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWE
VLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESE
QRPPFSQLHRFLAEDALNTV"
BASE COUNT 689 a 1082 c 1090 g 748 t
ORIGIN
1 gccgccgaag aggccccgct cccgggtcgg acgcctgggt ctgccgggaa gagcgatgag
61 agagatgctg cccccacccc cttaggcccg agggatcagg agctatggga ccagaggccc
121 tgtcatcttt actgctgctg ctcttggtgg caagtggaga tgctgacatg aagggacatt
181 ttgatcctgc caagtgccgc tatgccctgg gcatgcagga ccggaccatc ccagacagtg
241 acatctctgc ttccagctcc tggtcagatt ccactgccgc ccgccacagc aggttggaga
301 gcagtgacgg ggatggggcc tggtgccccg cagggtcggt gtttcccaag gaggaggagt
361 acttgcaggt ggatctacaa cgactgcacc tggtggctct ggtgggcacc cagggacggc
421 atgccggggg cctgggcaag gagttctccc ggagctaccg gctgcgttac tcccgggatg
481 gtcgccgctg gatgggctgg aaggaccgct ggggtcagga ggtgatctca ggcaatgagg
541 accctgaggg agtggtgctg aaggaccttg ggccccccat ggttgcccga ctggttcact
601 tctacccccg ggctgaccgg gtcatgagcg tctgtctgcg ggtagagctc tatggctgcc
661 tctggaggga tggactcctg tcttacaccg cccctgtggg gcagacaatg tatttatctg
721 aggccgtgta cctcaacgac tccacctatg acggacatac cgtgggcgga ctgcagtatg
781 ggggtctggg ccagctggca gatggtgtgg tggggctgga tgactttagg aagagtcagg
841 agctgcgggt ctggccaggc tatgactatg tgggatggag caaccacagc ttctccagtg
901 gctatgtgga gatggagttt gagtttgacc ggctgagggc cttccaggct atgcaggtcc
961 actgtaacaa catgcacacg ctgggagccc gtctgcctgg cggggtggaa tgtcgcttcc
1021 ggcgtggccc tgccatggcc tgggaggggg agcccatgcg ccacaaccta gggggcaacc
1081 tgggggaccc cagagcccgg gctgtctcag tgccccttgg cggccgtgtg gctcgctttc
1141 tgcagtgccg cttcctcttt gcggggccct ggttactctt cagcgaaatc tccttcatct
1201 ctgatgtggt gaacaattcc tctccggcac tgggaggcac cttcccgcca gccccctggt
1261 ggccgcctgg cccacctccc accaacttca gcagcttgga gctggagccc agaggccagc
1321 agcccgtggc caaggccgag gggagcccga ccgccatcct catcggctgc ctggtggcca
1381 tcatcctgct cctgctgctc atcattgccc tcatgctctg gcggctgcac tggcgcaggc
1441 tcctcagcaa ggctgaacgg agggtgttgg aagaggagct gacggttcac ctctctgtcc
1501 ctggggacac tatcctcatc aacaaccgcc caggtcctag agagccaccc ccgtaccagg
1561 agccccggcc tcgtgggaat ccgccccact ctgctccctg tgtccccaat ggctctgcct
1621 acagtgggga ctatatggag cctgagaagc caggcgcccc gcttctgccc ccacctcccc
1681 agaacagcgt cccccattat gccgaggctg acattgttac cctgcagggc gtcaccgggg
1741 gcaacaccta tgctgtgcct gcactgcccc caggggcagt cggggatggg ccccccagag
1801 tggatttccc tcgatctcga ctccgcttca aggagaagct tggcgagggc cagtttgggg
1861 aggtgcacct gtgtgaggtc gacagccctc aagatctggt cagtcttgat ttccccctta
1921 atgtgcgtaa gggacaccct ttgctggtag ctgtcaagat cttacggcca gatgccacca
1981 agaatgccag gaatgatttc ctgaaagagg tgaagatcat gtcgaggctc aaggacccaa
2041 acatcattcg gctgctgggc gtgtgtgtgc aggacgaccc cctctgcatg attactgact
2101 acatggagaa cggcgacctc aaccagttcc tcagtgccca ccagctggag gacaaggcag
2161 ccgagggggc ccctggggac gggcaggctg cgcaggggcc caccatcagc taccaaatgc
2221 tgctgcatgt ggcagcccag atcgcctccg gcatgcgcta tctggccaca ctcaactttg
2281 tacatcggga cctggccacg cggaactgcc tagttgggga aaatttcacc atcaaaatcg
2341 cagactttgg catgagccgg aacctctatg ctggggacta ttaccgtgtg cagggccggg
2401 cagtgctgcc catccgctgg atggcctggg agtgcatcct catggggaag ttcacgactg
2461 cgagtgacgt gtgggccttt ggtgtgaccc tgtgggaggt gctgatgctc tgtagggccc
2521 agccctttgg gcagctcacc gacgagcagg tcatcgagaa cgcgggggag ttcttccggg
2581 accagggccg gcaggtgtac ctgtcccggc cgcctgcctg cccgcagggc ctatatgagc
2641 tgatgcttcg gtgctggagc cgggagtctg agcagcgacc acccttttcc cagctgcatc
2701 ggttcctggc agaggatgca ctcaacacgg tgtgaatcac acatccagct gcccctccct
2761 cagggagcga tccaggggaa gccagtgaca ctaaaacaag aggacacaat ggcacctctg
2821 cccttcccct cccgacagcc catcacctct aatagaggca gtgagactgc aggtgggctg
2881 ggcccaccca gggagctgat gccccttctc cccttcctgg acacacactc atgtcccctt
2941 cctgttcttc cttcctagaa gcccctgtcg cccacccagc tggtcctgtg gatgggatcc
3001 tctccaccct cctctagcca tcccttgggg aagggtgggg agaaatatag gatagacact
3061 ggacatggcc cattggagca cctgggcccc actggacaac actgattcct ggagaggtgg
3121 ctgcgccccc agcttctctc tccctgtcac acactggacc ccactggctg agaatctggg
3181 ggtgaggagg acaagaagga gaggaaaatg tttccttgtg cctgctcctg tacttgtcct
3241 cagcttgggc ttcttcctcc tccatcacct gaaacactgg acctgggggt agccccgccc
3301 cagccctcag tcacccccac ttcccacttg cagtcttgta gctagaactt ctctaagcct
3361 atacgtttct gtggagtaaa tattgggatt ggggggaaag agggagcaac ggcccatagc
3421 cttggggttg gacatctcta gtgtagctgc cacattgatt tttctataat cacttggggt
3481 ttgtacattt ttggggggag agacacagat ttttacacta atatatggac ctagcttgag
3541 gcaattttaa tcccctgcac taggcaggta ataataaagg ttgagttttc cacaaaaaaa
3601 aaaaaaaaa
//