LOCUS BC070041 3829 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens lipase, hormone-sensitive, mRNA (cDNA clone MGC:87080
IMAGE:5296155), complete cds.
ACCESSION BC070041
VERSION BC070041.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3829)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3829)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-MAY-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 168 Row: d Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21328445.
FEATURES Location/Qualifiers
source 1..3829
/db_xref="H-InvDB:HIT000263999"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87080 IMAGE:5296155"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3829
/gene="LIPE"
/gene_synonym="HSL"
/gene_synonym="LHS"
/db_xref="GeneID:3991"
/db_xref="HGNC:HGNC:6621"
/db_xref="MIM:151750"
CDS 278..3508
/gene="LIPE"
/gene_synonym="HSL"
/gene_synonym="LHS"
/codon_start=1
/product="lipase, hormone-sensitive"
/protein_id="AAH70041.1"
/db_xref="GeneID:3991"
/db_xref="HGNC:HGNC:6621"
/db_xref="MIM:151750"
/translation="MEPGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQG
SNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQ
RVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQ
AKPGAKREPSAPTESTSQETPEQSDKQTTPVQGAKSKQGSLTELGFLTKLQELSIQRS
ALEWKALSEWVTDSESESDVGSSSDTDSPATMGGMVAQGVKLGFKGKSGYKVMSGYSG
TSPHEKTSARNHRHYQDTASRLIHNMDLRTMTQSLVTLAEDNIAFFSSQGPGETAQRL
SGVFAGVREQALGLEPALGRLLGVAHLFDLDPETPANGYRSLVHTARCCLAHLLHKSR
YVASNRRSIFFRTSHNLAELEAYLAALTQLRALVYYAQRLLVTNRPGVLFFEGDEGLT
ADFLREYVTLHKGCFYGRCLGFQFTPAIRPFLQTIYIGLVSFGEHYKRNETGLSVAAS
SLFTSGRFAIDPELRGAEFERITQNLDVHFWKAFWNITEMEVLSSLANMASATVRVSR
LLSLPPEAFEMPLTADPTLTVTISPPLAHTGPGPVLVRLISCDLREGQDSEELSSLIK
SNGQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQTSRSHEPYLKSWAQELGAPIISID
YSLAPEAPFPRALEECFFAYCWAIKHCALLGSTGERICLAGDSAGGNLCFTVALRAAA
YGVRVPDGIMAAYPATMLQPAASPSRLLSLMDPLLPLSVLSKCVSAYAGAKTEDHSNS
DQKALGMMGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMSEPIAEPMRRSVSE
AALAQPQGPLGTDSLKNLTLRDLSLRGNSETSSDTPEMSLSAETLSPSTPSDVNFLLP
PEDAGEEAEAKNELSPMDRGLGVRAAFPEGFHPRRSSQGATQMPLYSSPIVKNPFMSP
LLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLPHGFLTLA
ALCRETRQAAELCVERIRLVLTPPAGAGPSGETGAAGVDGGCGGRH"
BASE COUNT 844 a 1226 c 1095 g 664 t
ORIGIN
1 cttcttgtaa gagagtgcta ggcacatagc ctcctcctat tcctaatcct cccaccaaag
61 aaagaggcac agagttcatt acttagtggg ggccagctgt gatcggccaa ctgccagctg
121 ccttaaaaag gaagaccagt gatgctagga tggagtgaaa cccaagagga agtgccatca
181 tgaggaatca atgagagatc tgtgaagaga gagggctggg tgggagccca gaaggataga
241 acctggaaga tcaatatctc ccgtgaggga aataacaatg gagccaggtt ctaagtcagt
301 gtctaggtca gactggcaac ctgaaccaca ccagaggcct ataaccccgc tagagcctgg
361 gccagaaaag acacccatag cccagccaga atcgaagact ctgcagggat ccaataccca
421 acagaagcct gcttcaaacc aaagacccct cacccagcag gagacccctg cacaacatga
481 tgctgaatcc cagaaggaac ctagagccca acaaaaatct gcttcacaag aggaatttct
541 tgccccacag aagcccgcac cacagcaatc accttacatc caaagggtgc tgctcactca
601 acaggaagct gcctcccagc agggacctgg gctaggaaaa gaatctataa ctcaacagga
661 gccagcattg agacaaagac atgtagccca gccagggcct gggccaggag agccacctcc
721 agctcaacaa gaagctgaat caacacctgc ggcccaggct aaacctggag ccaaaaggga
781 gccatctgcc ccgactgaat ctacgtccca agagacacct gaacagtcag acaagcaaac
841 aacgccagtc cagggagcca aatccaagca gggatctttg acagagctgg gatttctaac
901 aaaacttcag gaactatcca tacagcgatc agccctagag tggaaggcac tttctgagtg
961 ggtcacagat tctgagtcag aatcagatgt gggatcatct tcagacacag attctccagc
1021 cacgatgggt ggaatggtgg cccagggagt gaagctaggc ttcaaaggaa aatctggtta
1081 taaagtgatg tcaggataca gtgggacgtc gccacatgag aaaaccagtg ctcggaatca
1141 cagacactac caggatacag cctcaaggct catccacaac atggacctgc gcacaatgac
1201 acagtcgctg gtgactctgg cggaggacaa catagccttc ttctcgagcc agggtcctgg
1261 ggaaacggcc cagcggctgt caggcgtttt tgccggtgta cgggagcagg cgctggggct
1321 ggagccggcc ctgggccgcc tgctgggtgt ggcgcacctc tttgacctgg acccagagac
1381 accggccaac gggtaccgca gcctagtgca cacagcccgc tgctgcctgg cgcacctcct
1441 gcacaaatcc cgctatgtgg cctccaaccg ccgcagcatc ttcttccgca ccagccacaa
1501 cctggccgag ctggaggcct acctggctgc cctcacccag ctccgcgctc tggtctacta
1561 cgcccagcgc ctgctggtta ccaatcggcc gggggtactc ttctttgagg gcgacgaggg
1621 gctcaccgcc gacttcctcc gggagtatgt cacgctgcat aagggatgct tctatggccg
1681 ctgcctgggc ttccagttca cgcctgccat ccggccattc ctgcagacca tctacattgg
1741 gctggtgtcc ttcggggagc actacaaacg caacgagaca ggcctcagtg tggccgccag
1801 ctctctcttc accagcggcc gctttgccat cgaccccgag ctgcgtgggg ctgagtttga
1861 gcggatcaca cagaacctgg acgtgcactt ctggaaagcc ttctggaaca tcaccgagat
1921 ggaagtgcta tcgtctctgg ccaacatggc atcggccacc gtgagggtaa gccgcctgct
1981 cagcctgcca cccgaagcct ttgagatgcc actgactgcc gaccccacgc tcacggtcac
2041 catctcaccc ccactggccc acacaggccc tgggcccgtc ctcgtcaggc tcatctcctg
2101 tgacctgcgt gaaggacagg acagtgagga gctcagcagc ctgataaagt ccaacggcca
2161 acggagcctg gagctgtggc cgcgccccca gcaggcaccc cgctcgcggt ccctgatagt
2221 gcacttccac ggcggtggct ttgtggccca gacctccaga tcccacgagc cctacctcaa
2281 gagctgggcc caggagctgg gcgcccccat catctccatc gactactccc tggcccctga
2341 ggcccccttc ccccgtgcgc tggaggagtg cttcttcgcc tactgctggg ccatcaagca
2401 ctgcgccctc cttggctcaa caggggaacg aatctgcctt gcgggggaca gtgcaggcgg
2461 gaacctctgc ttcaccgtgg ctcttcgggc agcagcctac ggggtgcggg tgccagatgg
2521 catcatggca gcctacccgg ccacaatgct gcagcctgcc gcctctccct cccgcctgct
2581 gagcctcatg gaccccttgc tgcccctcag tgtgctctcc aagtgtgtca gcgcctatgc
2641 tggtgcaaag acggaggacc actccaactc agaccagaaa gccctcggca tgatggggct
2701 ggtgcggcgg gacacagccc tgctcctccg agacttccgc ctgggtgcct cctcatggct
2761 caactccttc ctggagttaa gtgggcgcaa gtcccagaag atgtcggagc ccatagcaga
2821 gccgatgcgc cgcagtgtgt ctgaagcagc actggcccag ccccagggcc cactgggcac
2881 ggattccctc aagaacctga ccctgaggga cttgagcctg aggggaaact ccgagacgtc
2941 gtcggacacc cccgagatgt cgctgtcagc tgagacactt agcccctcca caccctccga
3001 tgtcaacttc ttattaccac ctgaggatgc aggggaagag gctgaggcca aaaatgagct
3061 gagccccatg gacagaggcc tgggcgtccg tgccgccttc cccgagggtt tccacccccg
3121 acgctccagc cagggtgcca cacagatgcc cctctactcc tcacccatag tcaagaaccc
3181 cttcatgtcg ccgctgctgg cacccgacag catgctcaag agcctgccac ctgtgcacat
3241 cgtggcgtgc gcgctggacc ccatgctgga cgactcggtc atgctcgcgc ggcgactgcg
3301 caacctgggc cagccggtga cgctgcgcgt ggtggaggac ctgccgcacg gcttcctgac
3361 cctagcggcg ctgtgccgcg agacgcgcca ggccgcagag ctgtgcgtgg agcgcatccg
3421 cctcgtcctc actcctcccg ccggagccgg gccgagcggg gagacggggg ctgcgggggt
3481 agacgggggc tgcggggggc gacactaaaa gcctgttgtt cccatctgcg ccggcctccg
3541 tcatgaatgc cttccgggcc gggcggaagg ggacgcgggc tgtgccttac ttaagtcggg
3601 ggtggcaagg gggcggggcg ggggcccgaa agctgagacc ctcgccacgg ggagggggac
3661 gcgcacacac accggtcacc gagacggctg gacctgcacg ccaccgctgc cttttgctgc
3721 tgctgctgcg gcgaccgccg cagggacggg gactggccct cccttgcagg tcggtttggt
3781 ttgttgtaaa taaaagtatt taattagttt ggcaaaaaaa aaaaaaaaa
//