LOCUS BC069244 1748 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens glutathione reductase, mRNA (cDNA clone MGC:78522
IMAGE:6422426), complete cds.
ACCESSION BC069244
VERSION BC069244.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1748)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1748)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 54 Row: n Column: 13.
FEATURES Location/Qualifiers
source 1..1748
/db_xref="H-InvDB:HIT000263398"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:78522 IMAGE:6422426"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_18"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1748
/gene="GSR"
/gene_synonym="MGC78522"
/db_xref="GeneID:2936"
/db_xref="HGNC:HGNC:4623"
/db_xref="MIM:138300"
CDS 92..1660
/gene="GSR"
/gene_synonym="MGC78522"
/codon_start=1
/product="glutathione reductase"
/protein_id="AAH69244.1"
/db_xref="GeneID:2936"
/db_xref="HGNC:HGNC:4623"
/db_xref="MIM:138300"
/translation="MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAM
ACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTC
VNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQN
NLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLG
ITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMIST
NCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIG
RVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRK
LAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPM
YHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTV
AIHPTSSEELVTLR"
BASE COUNT 433 a 458 c 492 g 365 t
ORIGIN
1 gtgaggctgc gcttgcccgg ggcccgcgcc cccctacccc ggggaccgcc cccgggccgc
61 ccgccccact tggcgcgcca cttccgcgtg catggccctg ctgccccgag ccctgagcgc
121 cggcgcggga ccgagctggc ggcgggcggc gcgcgccttc cgaggcttcc tgctgcttct
181 gcccgagccc gcggccctca cgcgcgccct ctcccgtgcc atggcctgca ggcaggagcc
241 gcagccgcag ggcccgccgc ccgctgctgg cgccgtggcc tcctatgact acctggtgat
301 cgggggcggc tcgggcgggc tggccagcgc gcgcagggcg gccgagctgg gtgccagggc
361 cgccgtggtg gagagccaca agctgggtgg cacttgcgtg aatgttggat gtgtacccaa
421 aaaggtaatg tggaacacag ctgtccactc tgaattcatg catgatcatg ctgattatgg
481 ctttccaagt tgtgagggta aattcaattg gcgtgttatt aaggaaaagc gggatgccta
541 tgtgagccgc ctgaatgcca tctatcaaaa caatctcacc aagtcccata tagaaatcat
601 ccgtggccat gcagccttca cgagtgatcc caagcccaca atagaggtca gtgggaaaaa
661 gtacaccgcc ccacacatcc tgatcgccac aggtggtatg ccctccaccc ctcatgagag
721 ccagatcccc ggtgccagct taggaataac cagcgatgga ttttttcagc tggaagaatt
781 gcccggccgc agcgtcattg ttggtgcagg ttacattgct gtggagatgg cagggatcct
841 gtcagccctg ggttctaaga catcactgat gatacggcat gataaggtac ttagaagttt
901 tgattcaatg atcagcacca actgcacgga ggagctggag aacgctggcg tggaggtgct
961 gaagttctcc caggtcaagg aggttaaaaa gactttgtcg ggcttggaag tcagcatggt
1021 tactgcagtt cccggtaggc taccagtcat gaccatgatt ccagatgttg actgcctgct
1081 ctgggccatt gggcgggtcc cgaataccaa ggacctgagt ttaaacaaac tggggattca
1141 aaccgatgac aagggtcata tcatcgtaga cgaattccag aataccaacg tcaaaggcat
1201 ctatgcagtt ggggatgtat gtggaaaagc tcttcttact ccagttgcaa tagctgctgg
1261 ccgaaaactt gcccatcgac tttttgaata taaggaagat tccaaattag attataacaa
1321 catcccaact gtggtcttca gccacccccc tattgggaca gtgggactca cggaagatga
1381 agccattcat aaatatggaa tagaaaatgt gaagacctat tcaacgagct ttaccccgat
1441 gtatcacgca gttaccaaaa ggaaaacaaa atgtgtgatg aaaatggtct gtgctaacaa
1501 ggaagaaaag gtggttggga tccatatgca gggacttggg tgtgatgaaa tgctgcaggg
1561 ttttgctgtt gcagtgaaga tgggagcaac gaaggcagac tttgacaaca cagtcgccat
1621 tcaccctacc tcttcagaag agctggtcac acttcgttga gaaccaggag acacgtgtgg
1681 cgggcagtgg gacccataga tcttctgaaa tgaaacaaat aatcacattg aaaaaaaaaa
1741 aaaaaaaa
//