LOCUS BC069194 3656 bp mRNA linear HUM 18-MAY-2004
DEFINITION Homo sapiens pleckstrin homology-like domain, family B, member 2,
mRNA (cDNA clone IMAGE:6370877), partial cds.
ACCESSION BC069194
VERSION BC069194.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3656)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3656)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (26-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
Schein, Asim Siddiqui, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 54 Row: m Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21955171.
FEATURES Location/Qualifiers
source 1..3656
/db_xref="H-InvDB:HIT000263354"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6370877"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_18"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..>3656
/gene="PHLDB2"
/gene_synonym="FLJ21791"
/gene_synonym="LL5b"
/gene_synonym="LL5beta"
/db_xref="GeneID:90102"
CDS 301..>3656
/gene="PHLDB2"
/gene_synonym="FLJ21791"
/gene_synonym="LL5b"
/gene_synonym="LL5beta"
/codon_start=1
/product="PHLDB2 protein"
/protein_id="AAH69194.1"
/db_xref="GeneID:90102"
/translation="MEEHSYIQKELDLQNGSLEEDSVVHSVENDSQNMMESLSPKKYS
SSLRFKANGDYSGSYLTLSQPVPAKRSPSPLGTSVRSSPSLAKIQGSKQFSYDGTDKN
IPMKPPTPLLNTTSSLSGYPLGRADFDHYTGRDSERALRLSEKPPYSKYSSRHKSHDN
VYSLGGLEGRKASGSLLAMWNGSSLSDAGPPPISRSGAASMPSSPKQARKMSIQDSLA
LQPKLTRHKELASENINLRTRKYSSSSLSHMGAYSRSLPRLYRATENQLTPLSLPPRN
SLGNSKRTKLGEKDLPHSVIDNDNYLNFSSLSSGALPYKTSASEGNPYVSSTLSVPAS
PRVARKMLLASTSSCASDDFDQASYVGTNPSHSLLAGESDRVFATRRNFSCGSVEFDE
ADLESLRQASGTPQPALRERKSSISSISGRDDLMDYHRRQREERLREQEMERLERQRL
ETILSLCAEYTKPDSRLSTGTTVEDVQKINKELEKLQLSDEESVFEEALMSPDTRYRC
HRKDSLPDADLASCGSLSQSSASFFTPRSTRNDELLSDLTRTPPPPSSTFPKASSESS
YLSILPKTPEGISEEQRSQELAAMEETRIVILNNLEELKQKIKDINDQMDESFRELDM
ECALLDGEQKSETTELMKEKEILDHLNRKIAELEKNIVGEKTKDADLLDVESKHFEDL
EFQQLEHESRLDEEKENLTQQLLREVAEYQRNIVSRKEKISALKKQANHIVQQAQREQ
DHFVKEKNNLIMMLQREKENLCNLEKKYSSLSGGKGFPVNPNTLKEGYISVNEINEPC
GNSTNLSPSTQFPADADAVATEPATAVLASQPQSKEHFRSLEERKKQHKEGLYLSDTL
PRKKTTSSISPHFSSATMGRSITPKAHLPLGQSNSCGSVLPSSLAAMAKDSESRRMLR
GYNHQQMSEGHRQKSEFYNRTASESNVYLNSFHYPDHSYKDQAFDTLSLDSSDSMETS
ISACSPDNISSASTSNIARIEEMERLLKQAHAEKTRLLESREREMEAKKRALEEEKRR
REILEKRLQEETSQRQKLIEKEVKIRERQRAQARPLTRYLPVRKEDFDLRSHVETAGH
NIDTCYHVSITEKTCRGFLIKMGGKKKKKK"
BASE COUNT 1104 a 885 c 895 g 772 t
ORIGIN
1 agaagctggc gcccagtgat ggggcaaaca gccatgccct tccagcagcc gtgaaagccc
61 caacagcaaa ctgcctggga gcggggcagg tcaccaactt cgttgctcga actccctggg
121 tgcccgccgc ggtggttaca aagggggtca agagtgcggg acccagccgc gcggagccca
181 ccattgcggc ccgaggggga cccgacgggg gcccgacggt gtggcgtggc gcaaggagcg
241 cgcctgcctt ctctcgccgc cgggaacggg ctgcaccaat ggccagattc cagcaagatt
301 atggaagagc atagctacat acaaaaggag ctagatttac aaaatggtag cttagaggaa
361 gactctgtgg tgcattctgt tgagaacgat tcccaaaaca tgatggagag cctcagccca
421 aagaaatact cttccagtct gagatttaaa gccaatggag actattctgg ctcctattta
481 accctctcac aacctgtgcc tgcaaagaga agcccttctc ctttgggaac cagtgtcaga
541 agcagcccct ccttagccaa aatccaggga agcaagcagt tctcttatga tggaactgac
601 aaaaatattc ctatgaaacc tccaactcct ttactcaaca ctacatcctc cctcagtgga
661 tatccacttg gaagagcaga ctttgatcat tatactggcc gggacagtga aagggccttg
721 aggctctcag agaagcctcc ctattccaaa tatagctcaa ggcataaatc gcatgacaat
781 gtctactctc ttggagggct ggaaggtcgg aaggcatctg gctcgctcct ggccatgtgg
841 aatggaagtt ccctgagtga tgctggcccg cctcctatca gcagatcggg agccgcaagc
901 atgccttcaa gcccaaagca agccaggaaa atgagcattc aggacagcct ggcgcttcaa
961 cccaagttaa ctagacacaa ggagcttgca tctgaaaaca tcaatttgag aactaggaag
1021 tactccagca gcagcctgag tcacatggga gcctacagcc gatcacttcc caggttgtac
1081 agagccacag agaaccagct gacacctctc agcttgcctc caagaaactc tctgggcaat
1141 tccaaacgaa caaaacttgg ggaaaaggat ctacctcata gcgtaataga caatgacaat
1201 taccttaatt tttcttcttt gagctcaggg gctttaccct ataaaacctc tgcttctgaa
1261 ggcaatcctt atgtaagttc taccctcagt gtccctgcca gtccacgagt ggctcggaag
1321 atgcttctgg cctccacctc ctcctgtgcc tctgatgact ttgatcaggc ttcatatgtg
1381 gggacaaacc cgagtcattc acttcttgct ggagagtcag acagagtttt tgcgaccagg
1441 aggaacttct cttgtggatc tgtggaattt gatgaggcag atttggaaag cctcagacag
1501 gcctcaggaa ccccccagcc tgcccttcgg gaacggaaaa gcagtattag ctccatttca
1561 ggacgtgatg acctgatgga ttatcaccgg cggcagaggg aggaaagact cagggagcag
1621 gaaatggagc gattggagag acagcgtctg gagaccatcc tcagtctctg tgctgaatac
1681 acaaagcctg acagtcgctt atctactggg accaccgtgg aagatgtgca gaaaatcaac
1741 aaggagcttg agaagctgca gctctctgat gaggagtctg tgtttgagga agccctcatg
1801 agccctgaca caagatacag gtgccaccgg aaagactccc tccctgatgc agacttggca
1861 agctgtggga gtctcagtca gagcagtgcc agcttcttta cccccaggag caccaggaat
1921 gatgaactac tcagtgacct cacccggact cctccaccac catcctccac ctttccgaaa
1981 gcttccagcg agtcctctta tctaagtatc ctaccaaaga ccccagaggg tataagtgaa
2041 gaacagagat ctcaggagtt ggctgcaatg gaagaaaccc ggatagtcat tctgaacaac
2101 ctcgaggaac ttaagcaaaa aatcaaagac ataaatgatc agatggatga gtctttcaga
2161 gagttggata tggaatgtgc tcttttggat ggagaacaga aatctgaaac aactgaactt
2221 atgaaggaga aggagatttt ggatcatcta aaccggaaaa tagctgaact ggaaaagaac
2281 attgttggtg aaaagaccaa ggatgctgac ctgttggatg ttgaaagcaa acactttgaa
2341 gacctggagt tccagcagct tgaacatgag agccgtctag atgaagaaaa ggagaacttg
2401 actcaacagc tcctgcgtga agttgctgaa tatcaacgga acatcgtttc tagaaaggaa
2461 aaaatttctg cattgaaaaa gcaagccaat cacattgttc agcaggctca gagagagcaa
2521 gatcattttg tgaaagaaaa gaataattta ataatgatgt tgcaaagaga aaaggagaat
2581 ctttgtaatt tggaaaagaa atactccagc ctctctgggg ggaaagggtt tcccgttaac
2641 cccaatactt taaaagaggg ctatatcagt gtaaatgaga ttaatgagcc gtgtggcaat
2701 tccacgaatc tatccccttc cactcagttt cctgctgatg ctgatgctgt tgccactgag
2761 cctgccacag ctgtgctggc gagccagcca cagagtaaag agcactttag aagtctggaa
2821 gaaaggaaaa aacagcataa agaaggcctc tatctgagtg atactttgcc tcgaaagaaa
2881 accacatctt ccatctcccc acatttcagc agtgctacta tggggagaag catcacccca
2941 aaggcccatc tgcccctagg acagagtaac agctgtggaa gtgtgctccc ttcctcactg
3001 gcagccatgg ccaaagactc agaatctcgg aggatgctca gaggttataa tcaccaacag
3061 atgagtgaag gacacaggca gaaatctgaa ttttataacc gcacagcatc tgaatcaaat
3121 gtctacttga atagtttcca ttatccagat cacagctaca aggaccaggc ctttgatact
3181 ctgagcctcg atagctctga tagcatggag accagcatct ctgcttgctc accagacaac
3241 atctctagtg ccagcacttc aaatattgct agaatagaag aaatggagag acttttgaag
3301 caggctcatg cagaaaagac gcggctgctc gaatccaggg aacgggaaat ggaagccaaa
3361 aaacgagccc tggaagaaga aaaacgacgc cgggaaatcc tggaaaaacg attacaggaa
3421 gaaactagcc agaggcagaa gttaatagaa aaggaagtaa aaataaggga gagacaaagg
3481 gcacaggctc gtcctttgac acgctacctg cctgtccgga aggaagactt tgatttgcgg
3541 agccatgtag agactgctgg ccacaatatt gacacctgtt accatgtatc aatcacagag
3601 aagacctgcc gaggattcct catcaaaatg ggtgggaaaa aaaaaaaaaa aaaaaa
//