LOCUS BC068558 2676 bp mRNA linear HUM 08-FEB-2007
DEFINITION Homo sapiens leucine rich repeat and Ig domain containing 1, mRNA
(cDNA clone MGC:87481 IMAGE:4797856), complete cds.
ACCESSION BC068558
VERSION BC068558.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2676)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2676)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 167 Row: c Column: 14.
FEATURES Location/Qualifiers
source 1..2676
/db_xref="H-InvDB:HIT000263115"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87481 IMAGE:4797856"
/tissue_type="Brain, hypothalamus"
/clone_lib="NIH_MGC_96"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2676
/gene="LINGO1"
/gene_synonym="LERN1"
/gene_synonym="UNQ201"
/db_xref="GeneID:84894"
/db_xref="HGNC:HGNC:21205"
/db_xref="MIM:609791"
CDS 444..2288
/gene="LINGO1"
/gene_synonym="LERN1"
/gene_synonym="UNQ201"
/codon_start=1
/product="LINGO1 protein"
/protein_id="AAH68558.1"
/db_xref="GeneID:84894"
/db_xref="HGNC:HGNC:21205"
/db_xref="MIM:609791"
/translation="MLAGGVRSMPSPLLACWQPILLLVLGSVLSGSATGCPPRYECSA
QDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVS
AVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDL
YNLRSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRH
LNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLA
VRHLVYLRFLNLSYNRISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVL
NVSGNQLTTLEESVFHSVGNLETLILDSNPLACDCRLLWVFRRRWRLNFNRQQPTCAT
PEFVQGKEFKDFPDVLLPNYFTCRRARIRDRKAQQVFVDEGHTVQFVCRADGDPPPAI
LWLSPRKHLVSAKSNGRLTVFPDGTLEVRYAQVQDNGTYLCIAANAGGNDSMPAHLHV
RSYSPDWPHQPNKTFAFISNQPGEGEANSTRATVPFPFDIKTLIIATTMGFISFLGVV
LFCLVLLFLWSRGKGNTKHNIEIEYVPRKSDAGISSADAPRKFNMKMI"
BASE COUNT 551 a 935 c 689 g 501 t
ORIGIN
1 attatacaga gatatttagc ctaatagaag ccgacagatc attcagggca gtaatgtact
61 ccggcttcaa gcgtgtagtt tcctcagcct gaactcccag attaaaggct ccttgcccag
121 cccgccctgt gccggtgcct gtgaccttga ctgcaatgat gggggatctt atgaccatga
181 cctggctacc ttgagtctgt ggggctacac agccttcagc ctgcatctcc agggctctga
241 ctctatccag ctcctggacc agctcccaag tctactcctg accccagcct gggccaaggg
301 gacttctcaa gctttgggac ccagcaggac acagcagcag tcaggtgcat gctgggaccg
361 cgacggacag gctgccgcac cccaggcccc cagaggccag tctgtttgcc tcccaacgcc
421 atctgaccca ggtgagcaag aggatgctgg cggggggcgt gaggagcatg cccagccccc
481 tcctggcctg ctggcagccc atcctcctgc tggtgctggg ctcagtgctg tcaggctcgg
541 ccacgggctg cccgccccgc tacgagtgct ccgcccagga ccgcgctgtg ctgtgccacc
601 gcaagcgctt tgtggcagtc cccgagggca tccccaccga gacgcgcctg ctggacctag
661 gcaagaaccg catcaaaacg ctcaaccagg acgagttcgc cagcttcccg cacctggagg
721 agctggagct caacgagaac atcgtgagcg ccgtggagcc cggcgccttc aacaacctct
781 tcaacctccg gacgctgggt ctccgcagca accgcctgaa gctcatcccg ctaggcgtct
841 tcactggcct cagcaacctg accaagctgg acatcagcga gaacaagatc gttatcctac
901 tggactacat gtttcaggac ctgtacaacc tcaggtcact ggaggttggc gacaatgacc
961 tcgtctacat ctctcaccgc gccttcagcg gcctcaacag cctggagcag ctgacgctgg
1021 agaaatgcaa cctgacctcc atccccaccg aggcgctgtc ccacctgcac ggcctcatcg
1081 tcctgaggct ccggcacctc aacatcaatg ccatccggga ctactccttc aagaggctgt
1141 accgactaaa ggtcttggag atctcccact ggccctactt ggacaccatg acacccaact
1201 gcctctacgg cctcaacctg acgtccctgt ccatcacaca ctgcaatctg accgctgtgc
1261 cctacctggc cgtccgccac ctagtctatc tccgcttcct caacctctcc tacaaccgca
1321 tcagcaccat tgagggctcc atgttgcatg agctgctccg gctgcaggag atccagctgg
1381 tgggcgggca gctggccgtg gtggagccct atgccttccg cggcctcaac tacctgcgcg
1441 tgctcaatgt ctctggcaac cagctgacca cactggagga atcagtcttc cactcggtgg
1501 gcaacctgga gacactcatc ctggactcca acccgctggc ctgcgactgt cggctcctgt
1561 gggtgttccg gcgccgctgg cggctcaact tcaaccggca gcagcccacg tgcgccacgc
1621 ccgagtttgt ccagggcaag gagttcaagg acttccctga tgtgctactg cccaactact
1681 tcacctgccg ccgcgcccgc atccgggacc gcaaggccca gcaggtgttt gtggacgagg
1741 gccacacggt gcagtttgtg tgccgggccg atggcgaccc gccgcccgcc atcctctggc
1801 tctcacccag aaagcacctg gtctcagcca agagcaatgg gcggctcaca gtcttccctg
1861 atggcacgct ggaggtgcgc tacgcccagg tacaggacaa cggcacgtac ctgtgcatcg
1921 cggccaacgc gggcggcaac gactccatgc ccgcccacct gcatgtgcgc agctactcgc
1981 ccgactggcc ccatcagccc aacaagacct tcgctttcat ctccaaccag ccgggcgagg
2041 gagaggccaa cagcacccgc gccactgtgc ctttcccctt cgacatcaag accctcatca
2101 tcgccaccac catgggcttc atctctttcc tgggcgtcgt cctcttctgc ctggtgctgc
2161 tgtttctctg gagccggggc aagggcaaca caaagcacaa catcgagatc gagtatgtgc
2221 cccgaaagtc ggacgcaggc atcagctccg ccgacgcgcc ccgcaagttc aacatgaaga
2281 tgatatgagg ccggggcggg gggcagggac ccccgggcgg ccgggcaggg gaaggggcct
2341 ggccgccacc tgctcactct ccagtccttc ccacctcctc cctacccttc tacacacgtt
2401 ctctttctcc ctcccgcctc cgtcccctgc tgccccccgc cagccctcac cacctgccct
2461 ccttctacca ggacctcaga agcccagacc tggggacccc acctacacag gggcattgac
2521 agactggagt tggaagccga cgaaccgaca cgcggcagag tcaataattc aataaaaaag
2581 ttacgaactt tctctgtaac ttgggtttca ataattatgg atttttatga aaacttgaaa
2641 taataaaaag agaaaaaaac caaaaaaaaa aaaaaa
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