LOCUS BC068541 3208 bp mRNA linear HUM 08-FEB-2007
DEFINITION Homo sapiens leucine rich repeat neuronal 2, mRNA (cDNA clone
MGC:87391 IMAGE:5301942), complete cds.
ACCESSION BC068541
VERSION BC068541.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3208)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3208)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 168 Row: g Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 42544232.
FEATURES Location/Qualifiers
source 1..3208
/db_xref="H-InvDB:HIT000263098"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87391 IMAGE:5301942"
/tissue_type="Brain, hypothalamus"
/clone_lib="NIH_MGC_96"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3208
/gene="LRRN2"
/gene_synonym="GAC1"
/gene_synonym="LRANK1"
/db_xref="GeneID:10446"
/db_xref="HGNC:HGNC:16914"
/db_xref="MIM:605492"
CDS 377..2518
/gene="LRRN2"
/gene_synonym="GAC1"
/gene_synonym="LRANK1"
/codon_start=1
/product="leucine rich repeat neuronal 2"
/protein_id="AAH68541.1"
/db_xref="GeneID:10446"
/db_xref="HGNC:HGNC:16914"
/db_xref="MIM:605492"
/translation="MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPR
SSYREATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQ
NSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRA
FSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSL
VLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRV
GPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHL
PQMETLMLNNNALSALHQQTAESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEP
QSTLCAEPPDLQRLPVREVPFREMTDHCLPLISPRSFPPSLQVASGESMVLHCRALAE
PEPEIYWVTPAGLRLTPAHAGRRYRVYPEGTLELRRVTAEEAGLYTCVAQNLVGADTK
TVSVVVGRALLQPGRDEGQGLELRVQETHPYHILLSWVTPPNTVSTNLTWSSASSLRG
QGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTKEATSCHRA
LGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVGGRRPLPPAWAFWGWSPPSVRVV
SAPLVLPWNPGRKLPRSSEGETLLPPLSQNS"
BASE COUNT 628 a 1055 c 915 g 610 t
ORIGIN
1 gagggcgccc gccgagcctc cccggcctgt gcagacggcg cgcgcggcgg gagggcgcgg
61 accagcgtcc ccagcccggc cccgggcgga aggcgagcgg agcgcggccg cgcgggcagc
121 agacggcaga cggtgcccgg cgcccacggg ggctgcccct gatggggcct ggcaatgact
181 gagcaggccc agccccagag gacaaggaag agaaggcata ttgaggaggg caagaagtga
241 cgcccggtgt agaatgactg ccctgggagg gtggttcctt gggccctggc agggttgctg
301 acccttaccc tgcaaaacac aaagagcagg actccagact cttcttgtga atggtcccct
361 gccctgcagc tccaccatga ggcttctcgt ggccccactc ttgctagctt gggtggctgg
421 tgccactgcc gctgtgcccg tggtaccctg gcatgttccc tgcccccctc agtgtgcctg
481 ccagatccgg ccctggtata cgccccgctc gtcctaccgc gaggctacca ctgtggactg
541 caatgaccta ttcctgacgg cagtcccccc ggcactcccc gcaggcacac agaccctgct
601 cctgcagagc aacagcattg tccgtgtgga ccagagtgag ctgggctacc tggccaatct
661 cacagagctg gacctgtccc agaacagctt ttcggatgcc cgagactgtg atttccatgc
721 cctgccccag ctgctgagcc tgcacctaga ggagaaccag ctgacccggc tggaggacca
781 cagctttgca gggctggcca gcctacagga actctatctc aaccacaacc agctctaccg
841 catcgccccc agggcctttt ctggcctcag caacttgctg cggctgcacc tcaactccaa
901 cctcctgagg gccattgaca gccgctggtt tgaaatgctg cccaacttgg agatactcat
961 gattggcggc aacaaggtag atgccatcct ggacatgaac ttccggcccc tggccaacct
1021 gcgtagcctg gtgctagcag gcatgaacct gcgggagatc tccgactatg ccctggaggg
1081 gctgcaaagc ctggagagcc tctccttcta tgacaaccag ctggcccggg tgcccaggcg
1141 ggcactggaa caggtgcccg ggctcaagtt cctagacctc aacaagaacc cgctccagcg
1201 ggtagggccg ggggactttg ccaacatgct gcaccttaag gagctgggac tgaacaacat
1261 ggaggagctg gtctccatcg acaagtttgc cctggtgaac ctccccgagc tgaccaagct
1321 ggacatcacc aataacccac ggctgtcctt catccacccc cgcgccttcc accacctgcc
1381 ccagatggag accctcatgc tcaacaacaa cgctctcagt gccttgcacc agcagacggc
1441 ggagtccctg cccaacctgc aggaggtagg tctccacggc aaccccatcc gctgtgactg
1501 tgtcatccgc tgggccaatg ccacgggcac ccgtgtccgc ttcatcgagc cgcaatccac
1561 cctgtgtgcg gagcctccgg acctccagcg cctcccggtc cgtgaggtgc ccttccggga
1621 gatgacggac cactgtttgc ccctcatctc cccacgaagc ttccccccaa gcctccaggt
1681 agccagtgga gagagcatgg tgctgcattg ccgggcactg gccgaacccg aacccgagat
1741 ctactgggtc actccagctg ggcttcgact gacacctgcc catgcaggca ggaggtaccg
1801 ggtgtacccc gaggggaccc tggagctgcg gagggtgaca gcagaagagg cggggctata
1861 cacctgtgtg gcccagaacc tggtgggggc tgacactaag acggttagtg tggttgtggg
1921 ccgtgctctc ctccagccag gcagggacga aggacagggg ctggagctcc gggtgcagga
1981 gacccacccc tatcacatcc tgctatcttg ggtcacccca cccaacacag tgtccaccaa
2041 cctcacctgg tccagtgcct cctccctccg gggccagggg gccacagctc tggcccgcct
2101 gcctcgggga acccacagct acaacattac ccgcctcctt caggccacgg agtactgggc
2161 ctgcctgcaa gtggcctttg ctgatgccca cacccagttg gcttgtgtat gggccaggac
2221 caaagaggcc acttcttgcc acagagcctt aggggaccgt cctgggctca ttgccatcct
2281 ggctctcgct gtccttctcc tggcagctgg gctagcggcc caccttggca caggccaacc
2341 caggaagggt gtgggtggga ggcggcctct ccctccagcc tgggctttct ggggctggag
2401 tcccccttct gtccgggttg tgtctgctcc cctcgtcctg ccctggaatc cagggaggaa
2461 gctgcccaga tcctcagaag gggagacact gttgccacca ttgtctcaaa attcttgaag
2521 ctcagcctgt tctcagcagt agagaaatca ctaggactac tttttaccaa aagagaagca
2581 gtctgggcca gatgccctgc caggaaaggg acatggaccc acgtgcttga ggcctggcag
2641 ctgggccaag acagatgggg ctttgtggcc ctgggggtgc ttctgcagcc tcgaaaaagt
2701 tgcccttacc tcctagggtc acctctgctg ccattctgag gaacatctcc aaggaacagg
2761 agggactttg gctagagcct cctgcctccc catcttctct ctgcccagag gctcctgggc
2821 ctggcttggc tgtcccctac ctgtgtcccc gggctgcacc ccttcctctt ctctttctct
2881 gtacagtctc agttgcttgc tcttgtgcct cctgggcaag ggctgaagga ggccactcca
2941 tctcacctcg gggggctgcc ctcaatgtgg gagtgacccc agccagatct gaaggacatt
3001 tgggagaggg atgcccagga acgcctcatc tcagcagcct gggctcggca ttccgaagct
3061 gactttctat aggcaatttt gtacctttgt ggagaaatgt gtcacctccc ccaacccgat
3121 tcactctttt ctcctgtttt gtaaaaaata aaaataaata ataacaataa tacgggggaa
3181 aggaacgaaa ggaaaaaaaa aaaaaaaa
//