LOCUS BC068513 3597 bp mRNA linear HUM 21-JUL-2005
DEFINITION Homo sapiens Rho guanine nucleotide exchange factor (GEF) 3, mRNA
(cDNA clone IMAGE:5264163), partial cds.
ACCESSION BC068513
VERSION BC068513.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3597)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3597)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-APR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 167 Row: k Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 9506400.
FEATURES Location/Qualifiers
source 1..3597
/db_xref="H-InvDB:HIT000263070"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5264163"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene <1..3597
/gene="ARHGEF3"
/gene_synonym="DKFZP434F2429"
/gene_synonym="GEF3"
/gene_synonym="STA3"
/gene_synonym="XPLN"
/db_xref="GeneID:50650"
CDS <1..1732
/gene="ARHGEF3"
/gene_synonym="DKFZP434F2429"
/gene_synonym="GEF3"
/gene_synonym="STA3"
/gene_synonym="XPLN"
/codon_start=2
/product="ARHGEF3 protein"
/protein_id="AAH68513.1"
/db_xref="GeneID:50650"
/translation="VESCPARSRLSVSVSPPPPGIVELGPPFAWEFCSRLGSAVTSQR
AGPAAAMVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPLSRVTSLANLI
PPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDV
CVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFG
TLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLD
HKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQ
QHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVVCCHGELK
NNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSL
RGAFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQA
GVLDSEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSC
GNSRHGESNV"
BASE COUNT 1046 a 798 c 831 g 922 t
ORIGIN
1 agtcgagtcc tgcccggcta gaagccggct gtcggtctcc gtgtcgccgc cgccgcccgg
61 catcgtggag ctggggcccc cttttgcctg ggagttttgt agtcgcctag ggtcagcggt
121 gacatcccaa agggcaggcc cggcagccgc catggtggcc aaggattacc ccttctacct
181 cacggtcaag agagcgaact gcagcctgga gctacctccg gccagcggtc cggccaagga
241 cgctgaggag cctagtaata aacgggtcaa acccctttcc cgagtcacgt cgctagcaaa
301 cctcatcccg cccgtgaagg ccacgccatt aaagcgcttc agtcaaaccc tgcagcgctc
361 cattagcttc cgcagtgaga gccgccctga catcctcgcc ccccgaccct ggtccagaaa
421 tgccgccccc tcgagcacga aacggagaga tagcaagctg tggagtgaga ccttcgatgt
481 gtgcgtcaat cagatgctta catccaagga aatcaaacgt caggaggcga tctttgagct
541 ttcccaagga gaagaagact tgatagaaga cttgaaatta gcaaaaaagg cctatcatga
601 ccccatgctg aaactctcca taatgacaga acaagagttg aatcaaattt ttggaacact
661 ggactctcta attcctctac atgaagagct ccttagtcag cttcgagatg ttaggaagcc
721 tgatggctcg actgaacatg ttggtcccat cctcgtgggc tggctccctt gcctcagctc
781 ctatgatagc tactgcagca atcaagtagc cgccaaagct ctgctggacc acaaaaagca
841 agatcaccga gtccaggatt tcctacagcg atgtttagaa tcccccttta gccgcaaact
901 agatctctgg aatttcctcg atattccaag aagccgcctg gtaaaatacc ctctgcttct
961 ccgagaaatc ttgaggcaca caccaaatga taatccagat cagcagcact tggaagaagc
1021 tataaatatc attcagggaa ttgtggcaga aatcaacacc aagactggtg aatctgaatg
1081 ccgctattat aaagagcggc ttctttactt ggaagaaggc cagaaagact ccctgatcga
1141 cagctctcga gtcgtgtgtt gtcatggtga actgaagaac aatcggggcg tgaaactgca
1201 tgttttcctg ttccaagaag tgcttgtgat cactcgagcc gtcacccaca atgagcagct
1261 ttgctaccag ctgtaccgtc agccaatccc cgtgaaagac ctcctgctgg aagacctcca
1321 ggatggagaa gtgaggctgg gtggctccct gcgaggggca ttcagcaaca atgagagaat
1381 taaaaacttc ttcagagtca gtttcaaaaa tggatcccaa agtcagaccc actcgctaca
1441 agccaatgac actttcaaca aacagcagtg gcttaactgt attcgtcaag ccaaagaaac
1501 agttttgtgt gctgccgggc aagctggggt gcttgactcc gagggatcgt tcctaaatcc
1561 caccaccggg agcagagagc tacagggaga aacaaaactt gagcagatgg accaatcgga
1621 cagtgagtca gactgtagta tggacacgag tgaggtcagc ctcgactgtg agcgcatgga
1681 acagacagac tcttcctgtg ggaacagcag gcatggtgaa agtaacgtct gacagaagca
1741 tgtgcacttc gggaagcagg cctgcatctt acctgtacag tatttgcatt ccacagatgg
1801 aacggtttgg agaagcactt tttcatactt ttgtgaaagt atacatgttg gcccagtctc
1861 tcgtatctgt acctttgtcc ctagtactgt aactgccaat ctgtctgtgt aagctggaat
1921 ctgtggcaac tattaccctg tgttgtattt cccaagtgtc tggatggatg gagaggtact
1981 caaacaagtt actttcagtt gtcctgctgg attttaaaaa aatagaaaaa gaatctcaaa
2041 actactgttt tacatagatt gtttgaagag tccttcctct tgtgcttctg taccactttc
2101 ccagctctta gatgtggtag ctaaaggcac ggaatttaga cggccttgta aatagggcat
2161 gaggaactca tctgtgtatt gggatggtat tagagagaga atcaggaaag accaactcat
2221 gaagtgaact tggtttgatc ttactcaact agaaagcttg aaaacatccc tggggattct
2281 gaaggcttaa ttttgcaaag gaggatgcat tgtctgaact ttgcaacttc atccagtgca
2341 agtttgatgc aagaatgtat taggacataa aatagaggct gaccttaaaa gggccaggac
2401 agaagcggct gccagctctg aatctttaac tgaaatgcac atggcaccag gaggtgtctc
2461 tcatagttgg ttgctagcct aaaacatcag aatagaaccc aaagggctta ggaaggcctg
2521 ccaggataac aagaaggccc tgtattcatt gtgtttcatc tgcctaggcc tactcattat
2581 tttagagaat gaatgaagca acaaggaaga gagaccatga ctctatcgat gacactgttt
2641 atagaaacac aggagaggaa gaatttggaa tgaaaagcac ttcgtcagaa ccttctgtgg
2701 gagccattga gagaaaagca tggtccagtg ccttctgaga aaggccagag ctttgggctt
2761 tcctgctctg cttttgggtc gtcaatttgc catctctggt tctgtgctat aatcagaatt
2821 gtaattatgt tctccagagg ccaatttcat taactctgat taattagaat cagctagcca
2881 gattagtaac ctctttgtcc agccttgatt tacagtgcag ggtaaagtgc agaccttaaa
2941 aacagctaag tacctagaag agctccctgc aagtgtaaat attaaggatg acctgtgcaa
3001 aattataccc acaccagcac tagtggtaat tattctaaat tattgccaaa aagttttttt
3061 taatctgtct ttcaagttta cagaaaagaa agcagtaaat gcattgatgt cattttatta
3121 tgtacatata tcatgtgcat tcaagctgtg tgacaagata tatcaatata aaaacaaggt
3181 atatacttta ttattttttg aaaacaagga tattgtgatc aattttaccc tgtaaaacat
3241 atttctgtat ttataggtct taaacatgat gaattttttc tattacaagt ttatttaaaa
3301 ctgctttctc aagtcgttat tgatacagca agtgaacctg ctgcagacag aagcagagga
3361 aagccaagaa cagcctttac tggtgaagaa aagaatgaat gattctttgt aggcgccatc
3421 agccactttt agaagccatc agccagtgtg ttgggaaaag aggtttgtca agtgttggcc
3481 tatgggaagg tggtcaatga atgttttgat gaaatgaatg tttttgtata atggccttaa
3541 acttttctgg aagtatttca aataaattac attattaagc caaaaaaaaa aaaaaaa
//