LOCUS BC067811 2213 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens cereblon, mRNA (cDNA clone MGC:87290 IMAGE:5264951),
complete cds.
ACCESSION BC067811
VERSION BC067811.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2213)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2213)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 167 Row: l Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 39545579.
FEATURES Location/Qualifiers
source 1..2213
/db_xref="H-InvDB:HIT000262779"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87290 IMAGE:5264951"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2213
/gene="CRBN"
/gene_synonym="MGC27358"
/db_xref="GeneID:51185"
/db_xref="HGNC:HGNC:30185"
/db_xref="MIM:609262"
CDS 15..1340
/gene="CRBN"
/gene_synonym="MGC27358"
/codon_start=1
/product="cereblon"
/protein_id="AAH67811.1"
/db_xref="GeneID:51185"
/db_xref="HGNC:HGNC:30185"
/db_xref="MIM:609262"
/translation="MAGEGDQQDAAHNMGNHLPLLPESEEEDEMEVEDQDSKEAKKPN
IINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFH
PQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIG
RQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQC
SYKWWQKYQRRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNP
IDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKN
EIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKI
CASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL"
BASE COUNT 741 a 401 c 441 g 630 t
ORIGIN
1 gcgtgtaaac agacatggcc ggcgaaggag atcagcagga cgctgcgcac aacatgggca
61 accacctgcc gctcctgcct gagagtgagg aagaagatga aatggaagtt gaagaccagg
121 atagtaaaga agccaaaaaa ccaaacatca taaattttga caccagtctg ccgacatcac
181 atacatacct aggtgctgat atggaagaat ttcatggcag gactttgcac gatgacgaca
241 gctgtcaggt gattccagtt cttccacaag tgatgatgat cctgattccc ggacagacat
301 tacctcttca gctttttcac cctcaagaag tcagtatggt gcggaattta attcagaaag
361 atagaacctt tgctgttctt gcatacagca atgtacagga aagggaagca cagtttggaa
421 caacagcaga gatatatgcc tatcgagaag aacaggattt tggaattgag atagtgaaag
481 tgaaagcaat tggaagacaa aggttcaaag tccttgagct aagaacacag tcagatggaa
541 tccagcaagc taaagtgcaa attcttcccg aatgtgtgtt gccttcaacc atgtctgcag
601 ttcaattaga atccctcaat aagtgccaga tatttccttc aaaacctgtc tcaagagaag
661 accaatgttc atataaatgg tggcagaaat accagaggag aaagtttcat tgtgcaaatc
721 taacttcatg gcctcgctgg ctgtattcct tatatgatgc tgagacctta atggacagaa
781 tcaagaaaca gctacgtgaa tgggatgaaa atctaaaaga tgattctctt ccttcaaatc
841 caatagattt ttcttacaga gtagctgctt gtcttcctat tgatgatgta ttgagaattc
901 agctccttaa aattggcagt gctatccagc gacttcgctg tgaattagac attatgaata
961 aatgtacttc cctttgctgt aaacaatgtc aagaaacaga aataacaacc aaaaatgaaa
1021 tattcagttt atccttatgt gggccgatgg cagcttatgt gaatcctcat ggatatgtgc
1081 atgagacact tactgtgtat aaggcttgca acttgaatct gataggccgg ccttctacag
1141 aacacagctg gtttcctggg tatgcctgga ctgttgccca gtgtaagatc tgtgcaagcc
1201 atattggatg gaagtttacg gccaccaaaa aagacatgtc acctcaaaaa ttttggggct
1261 taacgcgatc tgctctgttg cccacgatcc cagacactga agatgaaata agtccagaca
1321 aagtaatact ttgcttgtaa acagatgtga tagagataaa gttagttatc taacaaattg
1381 gttatattct aagatctgct ttggaaatta ttgcctctga tacataccta agtaaacata
1441 acattaatac ctaagtaaac ataacattac ttggagggtt gcagtttcta agtgaaactg
1501 tatttgaaac ttttaagtat actttaggaa acaagcatga acggcagtct agaataccag
1561 aaacatctac ttgggtagct tggtgccatt atcctgtgga atctgatatg tctggtagcg
1621 tgtcattgat gggacatgaa gacatctttg gaaatgatga gattatttcc tgtgttaaaa
1681 aaaaaaaaaa aatcttaaat tcctacaatg tgaaactgaa actaataatt tgatcctgat
1741 gtatgggaca gcgtatctgt accagtgctc taaataacaa aagctagggt gacaagtaca
1801 tgttcctttt ggaaagaagc aaggcaatgt atattaatta ttctaaaagg gctttgttcc
1861 tttccatttt ctttaacttc tctgagatac tgatttgtaa attttgaaaa ttagttaaaa
1921 tatgcagttt tttgagccca cgaatagttg tcatttcctt tatgtgcctg ttagtaaaaa
1981 gtagtattgt gtatttgctc agtatctgaa ctataagccc atttatactg ttccatacaa
2041 aagctatttt tcaaaaatta atttgaacca aaactactac tatagggaaa agatgccaaa
2101 acatgtcccc tcacccaggc taaacttgat actgtattat tttgttcaat gtaaattgaa
2161 gaaaatctgt aagtaagtaa accttaagtg tgaaactaaa aaaaaaaaaa aaa
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