LOCUS BC067508 1789 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens interleukin 1 receptor, type I, mRNA (cDNA clone
MGC:79371 IMAGE:7002111), complete cds.
ACCESSION BC067508
VERSION BC067508.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1789)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1789)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Narayan Bhat
cDNA Library Preparation: Bhat Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 172 Row: h Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27894331.
FEATURES Location/Qualifiers
source 1..1789
/db_xref="H-InvDB:HIT000262666"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:79371 IMAGE:7002111"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_195"
/lab_host="DH10B"
/note="Vector: pDNR-Dual"
gene 1..1789
/gene="IL1R1"
/gene_synonym="CD121A"
/gene_synonym="D2S1473"
/gene_synonym="IL-1R-alpha"
/gene_synonym="P80"
/db_xref="GeneID:3554"
/db_xref="HGNC:HGNC:5993"
/db_xref="MIM:147810"
CDS 65..1774
/gene="IL1R1"
/gene_synonym="CD121A"
/gene_synonym="D2S1473"
/gene_synonym="IL-1R-alpha"
/gene_synonym="P80"
/codon_start=1
/product="interleukin 1 receptor, type I"
/protein_id="AAH67508.1"
/db_xref="GeneID:3554"
/db_xref="HGNC:HGNC:5993"
/db_xref="MIM:147810"
/translation="MKVLLRLICFIALLISSLEADKCKEREEKIILVSSANEIDVRPC
PLNPNEHKGTITWYKDDSKTPVSTEQASRIHQHKEKLWFVPAKVEDSGHYYCVVRNSS
YCLRIKISAKFVENEPNLCYNAQAIFKQNLPVAGDGGLVCPYMEFFKNENNELPKLQW
YKDCKPLLLDNIHFSGVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFITL
EENKPTRPVIVSPANETMEVDLGSQIQLICNVTGQLSDIAYWKWNGSVIDEDDPVLGE
DYYSVENPANKRRSTLITVLNISEIESRFYKHPFTCFAKNTHGIDAAYIQLIYPVTNF
QKHMIGICVTLTVIIVCSVFIYKIFKIDIVLWYRDSCYDFLPIKASDGKTYDAYILYP
KTVGEGSTSDCDIFVFKVLPEVLEKQCGYKLFIYGRDDYVGEDIVEVINENVKKSRRL
IIILVRETSSFSWLGGSSEEQIAMYNALVQDGIKVVLLELEKIQDYEKMPESIKFIKQ
KHGAIRWSGDFTQGPQSAKTRFWKNVRYHMPVQRRSPSSKHQLLSPATKEKLQREAHV
PLG"
BASE COUNT 576 a 330 c 394 g 489 t
ORIGIN
1 atggtgactc cctcctgaga agctggaccc cttggtaaaa gacaaggcct tctccaagaa
61 gaatatgaaa gtgttactca gacttatttg tttcatagct ctactgattt cttctctgga
121 ggctgataaa tgcaaggaac gtgaagaaaa aataatttta gtgtcatctg caaatgaaat
181 tgatgttcgt ccctgtcctc ttaacccaaa tgaacacaaa ggcactataa cttggtataa
241 agatgacagc aagacacctg tatctacaga acaagcctcc aggattcatc aacacaaaga
301 gaaactttgg tttgttcctg ctaaggtgga ggattcagga cattactatt gcgtggtaag
361 aaattcatct tactgcctca gaattaaaat aagtgcaaaa tttgtggaga atgagcctaa
421 cttatgttat aatgcacaag ccatatttaa gcagaaccta cccgttgcag gagacggagg
481 acttgtgtgc ccttatatgg agttttttaa aaatgaaaat aatgagttac ctaaattaca
541 gtggtataag gattgcaaac ctctacttct tgacaatata cactttagtg gagtcaaaga
601 taggctcatc gtgatgaatg tggctgaaaa gcatagaggg aactatactt gtcatgcatc
661 ctacacatac ttgggcaagc aatatcctat tacccgggta atagaattta ttactctaga
721 ggaaaacaaa cccacaaggc ctgtgattgt gagcccagct aatgagacaa tggaagtaga
781 cttgggatcc cagatacaat tgatctgtaa tgtcaccggc cagttgagtg acattgctta
841 ctggaagtgg aatgggtcag taattgatga agatgaccca gtgctagggg aagactatta
901 cagtgtggaa aatcctgcaa acaaaagaag gagtaccctc atcacagtgc ttaatatatc
961 ggaaattgaa agtagatttt ataaacatcc atttacctgt tttgccaaga atacacatgg
1021 tatagatgca gcatatatcc agttaatata tccagtcact aatttccaga agcacatgat
1081 tggtatatgt gtcacgttga cagtcataat tgtgtgttct gttttcatct ataaaatctt
1141 caagattgac attgtgcttt ggtacaggga ttcctgctat gattttctcc caataaaagc
1201 ttcagatgga aagacctatg acgcatatat actgtatcca aagactgttg gggaagggtc
1261 tacctctgac tgtgatattt ttgtgtttaa agtcttgcct gaggtcttgg aaaaacagtg
1321 tggatataag ctgttcattt atggaaggga tgactacgtt ggggaagaca ttgttgaggt
1381 cattaatgaa aacgtaaaga aaagcagaag actgattatc attttagtca gagaaacatc
1441 aagcttcagc tggctgggtg gttcatctga agagcaaata gccatgtata atgctcttgt
1501 tcaggatgga attaaagttg tcctgcttga gctggagaaa atccaagact atgagaaaat
1561 gccagaatcg attaaattca ttaagcagaa acatggggct atccgctggt caggggactt
1621 tacacaggga ccacagtctg caaagacaag gttctggaag aatgtcaggt accacatgcc
1681 agtccagcga cggtcacctt catctaaaca ccagttactg tcaccagcca ctaaggagaa
1741 actgcaaaga gaggctcacg tgcctctcgg gtagcatgga gaacttgcc
//