LOCUS BC067442 1547 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cytochrome P450, family 8, subfamily B, polypeptide 1,
mRNA (cDNA clone MGC:79269 IMAGE:7002146), complete cds.
ACCESSION BC067442
VERSION BC067442.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1547)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1547)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (19-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Narayan Bhat
cDNA Library Preparation: Bhat Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 172 Row: h Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13929428.
FEATURES Location/Qualifiers
source 1..1547
/db_xref="H-InvDB:HIT000262600"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:79269 IMAGE:7002146"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_195"
/lab_host="DH10B"
/note="Vector: pDNR-Dual"
gene 1..1547
/gene="CYP8B1"
/gene_synonym="CP8B"
/gene_synonym="CYP12"
/db_xref="GeneID:1582"
/db_xref="HGNC:HGNC:2653"
/db_xref="MIM:602172"
CDS 34..1539
/gene="CYP8B1"
/gene_synonym="CP8B"
/gene_synonym="CYP12"
/codon_start=1
/product="cytochrome P450, family 8, subfamily B,
polypeptide 1"
/protein_id="AAH67442.1"
/db_xref="GeneID:1582"
/db_xref="HGNC:HGNC:2653"
/db_xref="MIM:602172"
/translation="MVLWGPVLGALLVVIAGYLCLPGMLRQRRPWEPPLDKGTVPWLG
HAMAFRKNMFEFLKRMRTKHGDVFTVQLGGQYFTFVMDPLSFGPILKDTQRKLDFGQY
AKKLVLKVFGYRSVQGDHEMIHSASTKHLRGDGLKDLNETMLDSLSFVMLTSKGWSLD
ASCWHEDSLFRFCYYILFTAGYLSLFGYTKDKEQDLLQAGELFMEFRKFDLLFPRFVY
SLLWPREWLEVGRLQRLFHKMLSVSHSQEKEGISNWLGNMLQFLREQGVPSAMQDKFN
FMMLWASQGNTGPTSFWALLYLLKHPEAIRAVREEATQVLGEARLETKQSFAFKLGAL
QHTPVLDSVVEETLRLRAAPTLLRLVHEDYTLKMSSGQEYLFRHGDILALFPYLSVHM
DPDIHPEPTVFKYDRFLNPNGSRKVDFFKTGKKIHHYTMPWGSGVSICPGRFFALSEV
KLFILLMVTHFDLELVDPDTPLPHVDPQRWGFGTMQPSHDVRFRYRLHPTE"
BASE COUNT 328 a 436 c 429 g 354 t
ORIGIN
1 cgtgtcgaga gcttaatccg caggagcata gccatggttc tctggggtcc agtgctggga
61 gctctgctgg tggtcattgc tggatacctg tgcctgccag ggatgctccg acaacgcagg
121 ccatgggagc cccctctgga caagggtacc gtgccctggc ttggccatgc catggctttc
181 cggaagaata tgtttgaatt tctgaagcgc atgaggacca agcatgggga tgtgttcaca
241 gtgcagctag ggggccagta cttcaccttc gtcatggacc ccctctcctt tggccccatc
301 ctcaaggaca cacagagaaa actagacttt gggcaatatg caaaaaaact ggtgctgaag
361 gtatttggat accgttcagt gcaaggggac catgagatga tacactcagc cagcaccaag
421 catctgaggg gggatggctt gaaggatctt aatgagacca tgctggacag cctgtccttt
481 gtaatgctga cgtccaaagg ctggagtctg gatgccagtt gctggcatga ggacagcctc
541 tttcgcttct gctattacat cttgttcaca gctggctacc tgagcttgtt cggctacacg
601 aaggacaagg agcaggacct gctacaggca ggagagttat tcatggagtt ccgcaagttt
661 gaccttcttt tcccaaggtt tgtctactcc ctgctgtggc cccgggagtg gctagaagtg
721 ggccgactcc agcgtctctt tcacaagatg ctctccgtga gccacagcca ggagaaggag
781 ggcatcagca actggctggg caacatgctt cagtttctga gggagcaggg ggtaccctca
841 gctatgcagg acaagttcaa cttcatgatg ctctgggcct cccaggggaa cacggggcct
901 acctctttct gggccctctt gtacctcctg aagcacccag aagctattcg ggctgtgagg
961 gaggaagcta cccaggtcct gggtgaggcc aggctggaga ccaagcagtc ctttgccttc
1021 aaactcggtg ccctgcaaca caccccagtt ctagacagcg tggtggagga gacgctgcgg
1081 ctgagggctg cacccaccct cctcaggttg gttcatgaag actataccct gaagatgtcc
1141 agtgggcagg agtatctgtt ccgccatgga gacatcctgg ccctctttcc ctacctctca
1201 gtgcacatgg accctgacat ccaccctgag cccaccgtct tcaagtacga tcgcttcctc
1261 aaccctaatg gcagccggaa agtggacttc ttcaagacag gcaagaagat ccaccactac
1321 accatgccct ggggttcggg cgtttccatc tgccctggga ggttctttgc actcagtgag
1381 gtgaagctct ttatcctgct tatggtcaca cactttgact tagagttggt ggaccctgac
1441 acaccactac cccatgttga cccgcagcgc tggggttttg gcaccatgca gcccagccac
1501 gatgtgcgct tccgctaccg cctgcatcct acagagtgag cttggcc
//