LOCUS BC067433 1503 bp mRNA linear HUM 30-JUN-2004
DEFINITION Homo sapiens cytochrome P450, family 2, subfamily E, polypeptide 1,
mRNA (cDNA clone MGC:79260 IMAGE:7002160), complete cds.
ACCESSION BC067433
VERSION BC067433.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1503)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1503)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (19-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Narayan Bhat
cDNA Library Preparation: Bhat Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 172 Row: i Column: 17
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13699837.
FEATURES Location/Qualifiers
source 1..1503
/db_xref="H-InvDB:HIT000262591"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:79260 IMAGE:7002160"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_195"
/lab_host="DH10B"
/note="Vector: pDNR-Dual"
gene 1..1503
/gene="CYP2E1"
/gene_synonym="CPE1"
/gene_synonym="CYP2E"
/gene_synonym="P450-J"
/gene_synonym="P450C2E"
/db_xref="GeneID:1571"
/db_xref="MIM:124040"
CDS 4..1485
/gene="CYP2E1"
/gene_synonym="CPE1"
/gene_synonym="CYP2E"
/gene_synonym="P450-J"
/gene_synonym="P450C2E"
/codon_start=1
/product="cytochrome P450, family 2, subfamily E,
polypeptide 1"
/protein_id="AAH67433.1"
/db_xref="GeneID:1571"
/db_xref="MIM:124040"
/translation="MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGN
LFQLELKNIPKSFTRLAQRFGPVFTLCVGSQRMVVMHGYKAVKEALLDYKDEFSGRGD
LPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRK
TQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLY
NNFPSFLHYLPGSHRKVIKNVAEVKEYVSERVKEHHQSLDPNCPRDLTDCLLVEMEKE
KHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIG
PSRIPAIKDRQEMPYMDAVVREIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPT
LDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLL
LCAILQHFNLKPLVDPKDIDLSPIHIGFGCIPPRYKLCVIPRS"
BASE COUNT 363 a 411 c 383 g 346 t
ORIGIN
1 cacatgtctg ccctcggagt caccgtggcc ctgctggtgt gggcggcctt cctcctgctg
61 gtgtccatgt ggaggcaggt gcacagcagc tggaatctgc ccccaggccc tttcccgctt
121 cccatcatcg ggaacctctt ccagttggaa ttgaagaata ttcccaagtc cttcacccgg
181 ttggcccagc gcttcgggcc ggtgttcacg ctgtgcgtgg gctcgcagcg catggtggtg
241 atgcacggct acaaggcggt gaaggaagcg ctgctggact acaaggacga gttctcgggc
301 agaggcgacc tccccgcgtt ccatgcgcac agggacaggg gaatcatttt taataatgga
361 cctacctgga aggacatccg gcggttttcc ctgaccaccc tccggaacta tgggatgggg
421 aaacagggca atgagagccg gatccagagg gaggcccact tcctgctgga agcactcagg
481 aagacccaag gccagccttt cgaccccacc ttcctcatcg gctgcgcgcc ctgcaacgtc
541 atagccgaca tcctcttccg caagcatttt gactacaatg atgagaagtt tctaaggctg
601 atgtatttgt ttaatgagaa cttccaccta ctcagcactc cctggctcca gctttacaat
661 aattttccca gctttctaca ctacttgcct ggaagccaca gaaaagtcat aaaaaatgtg
721 gctgaagtaa aagagtatgt gtctgaaagg gtgaaggagc accatcaatc tctggacccc
781 aactgtcccc gggacctcac cgactgcctg ctcgtggaaa tggagaagga aaagcacagt
841 gcagagcgct tgtacacaat ggacggtatc accgtgactg tggccgacct gttctttgcg
901 gggacagaga ccaccagcac aactctgaga tatgggctcc tgattctcat gaaataccct
961 gagatcgaag agaagctcca tgaagaaatt gacagggtga ttgggccaag ccgaatccct
1021 gccatcaagg ataggcaaga gatgccctac atggatgctg tggtgcgtga gattcagcgg
1081 ttcatcaccc tcgtgccctc caacctgccc catgaagcaa cccgagacac cattttcaga
1141 ggatacctca tccccaaggg cacagtcgta gtgccaactc tggactctgt tttgtatgac
1201 aaccaagaat ttcctgatcc agaaaagttt aagccagaac acttcctgaa tgaaaatgga
1261 aagttcaagt acagtgacta tttcaagcca ttttccacag gaaaacgagt gtgtgctgga
1321 gaaggcctgg ctcgcatgga gttgtttctt ttgttgtgtg ccattttgca gcattttaat
1381 ttgaagcctc tcgttgaccc aaaggatatc gacctcagcc ctatacatat tgggtttggc
1441 tgtatcccac cacgttacaa actctgtgtc attccccgct catgagtgtg tggaggacac
1501 cct
//