LOCUS BC067260 2977 bp mRNA linear HUM 19-MAR-2007
DEFINITION Homo sapiens sorbin and SH3 domain containing 3, mRNA (cDNA clone
MGC:74729 IMAGE:6186182), complete cds.
ACCESSION BC067260
VERSION BC067260.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2977)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2977)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. James R. Lupski
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 141 Row: e Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 63999695.
FEATURES Location/Qualifiers
source 1..2977
/db_xref="H-InvDB:HIT000262505"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:74729 IMAGE:6186182"
/tissue_type="Peripheral Nervous System, dorsal root
ganglion"
/clone_lib="Lupski_dorsal_root_ganglion"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2977
/gene="SORBS3"
/gene_synonym="SCAM-1"
/gene_synonym="SCAM1"
/gene_synonym="SH3D4"
/gene_synonym="vinexin"
/db_xref="GeneID:10174"
/db_xref="HGNC:HGNC:30907"
/db_xref="MIM:610795"
CDS 127..2142
/gene="SORBS3"
/gene_synonym="SCAM-1"
/gene_synonym="SCAM1"
/gene_synonym="SH3D4"
/gene_synonym="vinexin"
/codon_start=1
/product="sorbin and SH3 domain containing 3"
/protein_id="AAH67260.2"
/db_xref="GeneID:10174"
/db_xref="HGNC:HGNC:30907"
/db_xref="MIM:610795"
/translation="MQGPPRSLRAGLSLDDFIPGHLQSHIGSSSRGTRVPVIRNGGSN
TLNFQFHDPAPRTVCNGGYTPRRDASQHPDPAWYQTWPGPGSKPSASTKIPASQHTQN
WSATWTKDSKRRDKRWVKYEGIGPVDESGMPIAPRSSVDRPRDWYRRMFQQIHRKMPD
LQLDWTFEEPPRDPRHLGAQQRPAHRPGPATSSSGRSWDHSEELPRSTFNYRPGAFST
VLQPSNQVLRRREKVDNVWTEESWNQFLQELETGQRPKKPLVDDPGEKPSQPIEVLLE
RELAELSAELDKDLRAIETRLPSPKSSPAPRRAPEQRPPAGPASAWSSSYPHAPYLGS
ARSLSPHKMADGGSPFLGRRDFVYPSSTRDPSASNGGGSPARREEKKRKAARLKFDFQ
AQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYVEVLPADEIPKPIKPPT
YQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPAS
YVQVSREPRLRLCDDGPQLPTSPRLTAAARSARHPSSPSALRSPADPTDLGGQTSPRR
TGFSFPTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTSQIHWTPYRAMYQYR
PQNEDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV"
BASE COUNT 659 a 1024 c 823 g 471 t
ORIGIN
1 gcagcagccg ggcagggatg ctcctgcgct cccgggcggc ctcgggccca gccacctgct
61 cgccggggaa gaggacacgc agaggagcag ctggcttgcc cggagtcctc ccaccttgac
121 ccaagcatgc agggcccacc ccgcagcctc cgcgctgggc tcagcctgga cgacttcatc
181 cctggccacc tccagtccca catagggtct tcctcccggg ggacacgggt gcccgtgatc
241 cggaatggtg gctccaacac ccttaatttc cagttccacg accccgcgcc caggactgtg
301 tgcaatgggg gctacacacc aagacgagat gcttcccagc acccggaccc tgcgtggtat
361 cagacctggc caggccctgg gagcaagccc tctgcaagca caaagatccc tgcctcccag
421 cacacccaga actggtcagc cacgtggacc aaggacagca agcgtcggga caagcgctgg
481 gtcaagtacg agggaatcgg gcccgtggac gagagcggca tgcccattgc cccccgatcc
541 agcgttgaca gacccagaga ctggtaccgg agaatgttcc agcagattca ccggaaaatg
601 ccagacttgc agctggactg gaccttcgag gagccaccca gagaccccag gcatctagga
661 gcccagcaaa gacctgccca caggcccggc ccggcaacat cttccagtgg aagaagctgg
721 gaccactctg aagagttacc tagaagcacc ttcaactaca gacctggagc attctccact
781 gtgctgcagc cctcaaatca ggtgctcaga cgccgggaaa aagtagacaa tgtctggacg
841 gaagagtcct ggaaccagtt tctgcaggaa ctagagactg ggcagaggcc caagaaaccg
901 ctggtggacg accctggtga gaagccctcc cagcccattg aggtgctgct ggagagagag
961 ctggccgagc tgagcgccga gctggacaag gacctgcggg caattgagac ccgactgccg
1021 tcccccaaga gctcgccggc gccccgacgg gccccggagc agcggccccc ggccggcccg
1081 gcctcagcct ggagctccag ctacccacat gcaccttacc tgggttccgc ccggtccctg
1141 agtccccaca aaatggctga tggaggaagc cccttcctag gtcggaggga ctttgtctac
1201 ccttcctcaa cccgagaccc tagtgcctct aacggagggg gcagcccagc caggagggaa
1261 gagaagaaga gaaaggccgc caggctcaag tttgacttcc aggcgcagtc ccccaaggag
1321 ctgactctgc agaagggtga cattgtctac atccacaagg aggtggacaa gaactggctg
1381 gagggagagc accacggccg cctgggcatc ttccctgcta attatgtgga ggtgctgccc
1441 gcagatgaga tccctaagcc catcaagccc ccgacctacc aggtgctgga gtatggagag
1501 gctgtggccc agtacacctt caagggggac ctggaggtgg agctgtcctt ccgcaaggga
1561 gagcacatct gcctgatccg caaggtgaac gagaactggt acgagggacg catcacgggc
1621 acggggcgcc aaggcatatt ccctgccagc tacgtgcagg tgtctcgtga accccggctc
1681 cggctctgtg acgacggccc ccagctcccc acgtctcccc gcctgaccgc tgccgcccgc
1741 tcagcccgtc accccagctc cccctcagcc ctgcgcagcc cagctgaccc caccgacttg
1801 gggggacaga cctccccccg tcgcactggc ttctccttcc ccacccagga gcctagaccc
1861 cagacccaga atcttggcac ccctggtcca gctctgtccc actctcgagg tcccagccat
1921 cccctggacc tggggacctc ctctcctaac acctctcaga tacactggac cccgtaccgg
1981 gcgatgtacc agtacaggcc ccagaacgaa gacgagctgg agctgcgcga gggggacagg
2041 gtggatgtca tgcagcagtg tgacgatggc tggtttgtgg gtgtctcccg gaggacccag
2101 aaattcggaa cgttccctgg aaattacgtt gccccggtgt gagtggtctc catggcaact
2161 tggagccagc caggatgggg tggggagcgg tggcactcgt gggagggaga ggacccccgc
2221 ccacatcctc cttccccagg acctgagctc ccagcatctg cagacgaccc ccgcagcctt
2281 tccctcggac ccccctcgaa gccccctgga ctgattccca cccacgactc acaggcattc
2341 ctcccacagc cctttcattt cctccccacc ccactcccca aatacagagg tctgctttga
2401 agcggagacc atttccaggc cttattgaga ccagacccca agtcccccac ccccatcctg
2461 ctccagcgtt tcctctaaca gggaccagct ctccgctttg cccccacggg gttcctctaa
2521 ccagaaccag cttcctagcc tcgtagagac caaaggccgc ccccgcctgc tggggttcct
2581 cccagcaccc cagcttgctg gctgccctct ttgccttctg gcctccagct gggtgtgggg
2641 gggcggagca aggcggggga cagacgcagc accttcttag cgatctaggc ctggcaagag
2701 ctctggcccc aaggcctcct cttcccaggg gctgccaagt cctggccctg gccctggcat
2761 atcaccccgc actgtggggc caggcaccac tagcctggct caaatattcc ccagggagac
2821 tgctgtgtgc tgcccgcctg cctgctggct ctcccccagc cccacatccc ctctggaaga
2881 gaatgtaaaa taaacctgga cacaagggaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2941 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//