LOCUS BC067132 2539 bp mRNA linear HUM 16-MAR-2004
DEFINITION Homo sapiens WD repeat domain 23, mRNA (cDNA clone MGC:74695
IMAGE:6170335), complete cds.
ACCESSION BC067132
VERSION BC067132.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2539)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2539)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 140 Row: p Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 20127644.
FEATURES Location/Qualifiers
source 1..2539
/db_xref="H-InvDB:HIT000262465"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:74695 IMAGE:6170335"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2539
/gene="WDR23"
/gene_synonym="GL014"
/gene_synonym="PRO2389"
/db_xref="GeneID:80344"
CDS 154..1794
/gene="WDR23"
/gene_synonym="GL014"
/gene_synonym="PRO2389"
/codon_start=1
/product="WDR23 protein"
/protein_id="AAH67132.1"
/db_xref="GeneID:80344"
/translation="MGSRNSSSAGSGSGDPSEGLPRRGAGLRRSEEEEEEDEDVDLAQ
VLAYLLRRGQVRLVQGGGAANLQFIQALLDSEEENDRAWDGRLGDRYNPPVDATPDTR
ELEFNEIKTQVELATGQLGLRRAAQKHSFPRMLHQRERGLCHRGSFSLGEQSRVISHF
LPNDLGFTDSYSQKAFCGIYSKDGQIFMSACQDQTIRLYDCRYGRFHKFKSIKARDVG
WSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPDERRFAVFSIAVSSD
GREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADISSQILFSGGDDAICKV
WDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREG
MEASRQAATQQNWDYRWQQVPKKAWRKLKLPGDSSLMTYRGHGVLHTLIRCRFSPIHS
TGQQFIYSGCSTGKVVVYDLLSGHIVKKLTNHKACVRDVSWHPFEEKIVSSSWDGNLR
LWQYRQAEYFQDDMPESEECASAPAPVPQSSTPFSSPQ"
misc_feature 658..1686
/gene="WDR23"
/gene_synonym="GL014"
/gene_synonym="PRO2389"
/note="WD40; Region: WD40 domain, found in a number of
eukaryotic proteins that cover a wide variety of functions
including adaptor/regulatory modules in signal
transduction, pre-mRNA processing and cytoskeleton
assembly"
/db_xref="CDD:cd00200"
BASE COUNT 578 a 670 c 730 g 561 t
ORIGIN
1 gagcgaagcg cgtgacggag gagcggttgg ccaacgcagt ggcggcagtc ggtgtaaaca
61 aggcctcgcg ccgctgcggg tcctgcgacc gctcctggct ggaggtgaca ggaggagccc
121 ccgcacagga cctaagaatg ctgtgaccag aagatgggat cgcggaacag cagcagtgca
181 ggatccgggt ccggagaccc ctccgagggc ttgccccgaa gaggggctgg cctgcgtcgg
241 agtgaggaag aggaagaaga ggatgaagat gtggatctgg cccaggtact ggcctatctc
301 ctccgcagag gccaagtgag gttggtgcag ggaggaggtg cagcaaattt acaattcatt
361 caggccctct tggactcaga ggaagagaat gacagagctt gggatggtcg tcttggggat
421 cgatacaacc cacctgtgga tgctacccct gacacccggg agctggaatt caatgagatc
481 aagacacaag tggaactggc cacagggcag ctggggctta ggcgggccgc ccagaagcac
541 agctttcctc gaatgttgca ccagagagaa cggggcctct gccatcgggg aagcttctcc
601 cttggagaac agtctcgagt gatatctcac ttcttgccca atgatctggg cttcactgat
661 agctactctc agaaggcttt ctgtggcatc tacagcaaag atggtcaaat attcatgtct
721 gcttgccaag accagacaat ccgactctat gactgccgat atggccgttt ccataaattc
781 aagagcatca aggcccgcga tgtaggctgg agcgtcttgg atgtggcctt cacccctgat
841 gggaaccact tcctctactc tagctggtct gattacattc atatctgcaa tatctatggt
901 gagggagata cacacactgc cctggatctc aggccagatg agcgtcgctt tgctgtcttc
961 tccattgctg tctcctcaga tggacgagaa gtactaggag gggccaatga tggctgcctg
1021 tatgtctttg accgagaaca gaaccggcgc acccttcaga ttgagtccca tgaggatgat
1081 gtgaatgcag tggcctttgc tgatataagc tcccaaatcc tgttctctgg gggagatgat
1141 gccatctgca aagtgtggga tcgacgcacc atgcgggagg atgaccccaa gcctgtgggt
1201 gcactggctg gacaccagga tggcatcacc ttcattgaca gcaagggtga tgcccggtat
1261 ctgatctcca actctaaaga ccagaccatc aaactctggg atatccgacg cttttccagc
1321 cgggaaggca tggaagcttc acgccaggct gccacacagc aaaactggga ctatcggtgg
1381 cagcaagtgc ccaaaaaagc ctggcggaag ctgaagctcc caggggacag ctccttgatg
1441 acctaccggg gccacggagt gctgcacacc ctcatccgct gccggttctc ccccattcat
1501 agcactggcc agcagttcat ctacagtggc tgctccactg gcaaagtggt tgtgtacgac
1561 cttctaagtg gccacattgt gaagaagctg accaaccaca aggcctgtgt gcgtgacgtc
1621 agttggcacc cctttgaaga gaagattgtc agcagttcgt gggacgggaa cctgcgtctg
1681 tggcagtacc gccaggctga gtacttccag gatgacatgc cagaatctga ggaatgtgcc
1741 agcgcccctg ccccagtgcc ccaatcctct acaccctttt cctcacccca gtagatccaa
1801 cctccagccc catatagggt gaacctcttg ataagctctc tgcctcctcc tccctttctc
1861 ccttgtgggg aatgtttgga ggaatcactg gcatttgatg gggaataaca taagcctggg
1921 ctctgagcct cagctgagcc ctggaagatt ctccccatgg ggcagagtgg tctccttacg
1981 tgctcacacc cagtcagctt gggtccctat ctctggccag agtttggcag gactgccatt
2041 atctggggtg tggcctctgc cagcaagaga agtgtcctgg gtgtttttaa tcatgtttga
2101 atgttagggg ttggatccta gagtagatgc ctgaggccac atctgaacag acctgtcagc
2161 caggcctgcc aggtcttcac gttgaggatt caactggcca atcacaggac aggtgtcctg
2221 gcctttcttc ctgaggtctc taggggaggg gcatgggtaa gggtgtttcc tcagcaccct
2281 cctggggtgg ggattatgtc tgctgtcatg tctgggtctt tagggtagga caggctgtgg
2341 tatgagaggc aggagtctcc acaaggcttc atgtggcccc ttatagggca ggccctgccc
2401 tctgggaagg tcccttcatg ctggaggcac acagctttaa ggaagtaggt tgaagtagga
2461 ctccttcgtc ctctcactgg ctttggctcc ctcaataaac tgtgtgggaa cctgaaaaaa
2521 aaaaaaaaaa aaaaaaaaa
//