LOCUS BC067111 3318 bp mRNA linear HUM 06-APR-2004
DEFINITION Homo sapiens filamin A, alpha (actin binding protein 280), mRNA
(cDNA clone IMAGE:4800733), partial cds.
ACCESSION BC067111
VERSION BC067111.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3318)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3318)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: James Cleaver, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 134 Row: n Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..3318
/db_xref="H-InvDB:HIT000262446"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4800733"
/tissue_type="Skin, normal"
/clone_lib="NCI_CGAP_Skn3"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene <1..3318
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/db_xref="GeneID:2316"
/db_xref="MIM:300017"
CDS <1..2954
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/codon_start=3
/product="FLNA protein"
/protein_id="AAH67111.1"
/db_xref="GeneID:2316"
/db_xref="MIM:300017"
/translation="QIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTF
DIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQG
GQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPTITDNK
DGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNK
PATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNE
QHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCL
LKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQG
LHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNY
IINIKFADQHVPGSPFSVKVTGEGRVKESITRRRRAPSVANVGSHCDLSLKIPEISIQ
DMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTV
GPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDR
KDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLK
VNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDV
KFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGAL
SVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPR
LVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSF
TVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEH
IPGSPYRVVVP"
misc_feature 3..239
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/note="IG_FLMN; Region: Filamin-type immunoglobulin
domains"
/db_xref="CDD:smart00557"
misc_feature 411..593
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/note="IG_FLMN; Region: Filamin-type immunoglobulin
domains"
/db_xref="CDD:smart00557"
misc_feature 597..857
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/note="Filamin; Region: Filamin/ABP280 repeat"
/db_xref="CDD:pfam00630"
misc_feature 891..1136
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/note="IG_FLMN; Region: Filamin-type immunoglobulin
domains"
/db_xref="CDD:smart00557"
misc_feature 1146..1418
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/note="IG_FLMN; Region: Filamin-type immunoglobulin
domains"
/db_xref="CDD:smart00557"
misc_feature 1527..1706
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/note="IG_FLMN; Region: Filamin-type immunoglobulin
domains"
/db_xref="CDD:smart00557"
misc_feature 1713..1973
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/note="Filamin; Region: Filamin/ABP280 repeat"
/db_xref="CDD:pfam00630"
misc_feature 1995..2261
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/note="Filamin; Region: Filamin/ABP280 repeat"
/db_xref="CDD:pfam00630"
misc_feature 2286..2549
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/note="Filamin; Region: Filamin/ABP280 repeat"
/db_xref="CDD:pfam00630"
misc_feature 2682..2939
/gene="FLNA"
/gene_synonym="ABP-280"
/gene_synonym="ABPX"
/gene_synonym="FLN"
/gene_synonym="FLN1"
/gene_synonym="FMD"
/gene_synonym="MNS"
/gene_synonym="NHBP"
/gene_synonym="OPD1"
/gene_synonym="OPD2"
/note="Filamin; Region: Filamin/ABP280 repeat"
/db_xref="CDD:pfam00630"
BASE COUNT 720 a 1004 c 995 g 599 t
ORIGIN
1 ttcagattgg ggaggagacg gtgatcactg tggacactaa ggcggcaggc aaaggcaaag
61 tgacgtgcac cgtgtgcacg cctgatggct cagaggtgga tgtggacgtg gtggagaatg
121 aggacggcac tttcgacatc ttctacacgg ccccccagcc gggcaaatac gtcatctgtg
181 tgcgctttgg tggcgagcac gtgcccaaca gccccttcca agtgacggct ctggctgggg
241 accagccctc ggtgcagccc cctctacggt ctcagcagct ggccccacag tacacctacg
301 cccagggcgg ccagcagact tgggccccgg agaggcccct ggtgggtgtc aatgggctgg
361 atgtgaccag cctgaggccc tttgaccttg tcatcccctt caccatcaag aagggcgaga
421 tcacagggga ggttcggatg ccctcaggca aggtggcgca gcccaccatc actgacaaca
481 aagacggcac cgtgaccgtg cggtatgcac ccagcgaggc tggcctgcac gagatggaca
541 tccgctatga caacatgcac atcccaggaa gccccttgca gttctatgtg gattacgtca
601 actgtggcca tgtcactgcc tatgggcctg gcctcaccca tggagtagtg aacaagcctg
661 ccaccttcac cgtcaacacc aaggatgcag gagagggggg cctgtctctg gccattgagg
721 gcccgtccaa agcagaaatc agctgcactg acaaccagga tgggacatgc agcgtgtcct
781 acctgcctgt gctgccgggg gactacagca ttctagtcaa gtacaatgaa cagcacgtcc
841 caggcagccc cttcactgct cgggtcacag gtgacgactc catgcgtatg tcccacctaa
901 aggtcggctc tgctgccgac atccccatca acatctcaga gacggatctc agcctgctga
961 cggccactgt ggtcccgccc tcgggccggg aggagccctg tttgctgaag cggctgcgta
1021 atggccacgt ggggatttca ttcgtgccca aggagacggg ggagcacctg gtgcatgtga
1081 agaaaaatgg ccagcacgtg gccagcagcc ccatcccggt ggtgatcagc cagtcggaaa
1141 ttggggatgc cagtcgtgtt cgggtctctg gtcagggcct tcacgaaggc cacacctttg
1201 agcctgcaga gtttatcatt gatacccgcg atgcaggcta tggtgggctc agcctgtcca
1261 ttgagggccc cagcaaggtg gacatcaaca cagaggacct ggaggacggg acgtgcaggg
1321 tcacctactg ccccacagag ccaggcaact acatcatcaa catcaagttt gccgaccagc
1381 acgtgcctgg cagccccttc tctgtgaagg tgacaggcga gggccgggtg aaagagagca
1441 tcacccgcag gcgtcgggct ccttcagtgg ccaacgttgg tagtcattgt gacctcagcc
1501 tgaaaatccc tgaaattagc atccaggata tgacagccca ggtgaccagc ccatcgggca
1561 agacccatga ggccgagatc gtggaagggg agaaccacac ctactgcatc cgctttgttc
1621 ccgctgagat gggcacacac acagtcagcg tgaagtacaa gggccagcac gtgcctggga
1681 gccccttcca gttcaccgtg gggcccctag gggaaggggg agcccacaag gtccgagctg
1741 ggggccctgg cctggagaga gctgaagctg gagtgccagc cgaattcagt atctggaccc
1801 gggaagctgg tgctggaggc ctggccattg ctgtcgaggg ccccagcaag gctgagatct
1861 cttttgagga ccgcaaggac ggctcctgtg gtgtggctta tgtggtccag gagccaggtg
1921 actacgaagt ctcagtcaag ttcaacgagg aacacattcc cgacagcccc ttcgtggtgc
1981 ctgtggcttc tccgtctggc gacgcccgcc gcctcactgt ttctagcctt caggagtcag
2041 ggctaaaggt caaccagcca gcctcttttg cagtcagcct gaacggggcc aagggggcga
2101 tcgatgccaa ggtgcacagc ccctcaggag ccctggagga gtgctatgtc acagaaattg
2161 accaagataa gtatgctgtg cgcttcatcc ctcgggagaa tggcgtttac ctgattgacg
2221 tcaagttcaa cggcacccac atccctggaa gccccttcaa gatccgagtt ggggagcctg
2281 ggcatggagg ggacccaggc ttggtgtctg cttacggagc aggtctggaa ggcggtgtca
2341 cagggaaccc agctgagttc gtcgtgaaca cgagcaatgc gggagctggt gccctgtcgg
2401 tgaccattga cggcccctcc aaggtgaaga tggattgcca ggagtgccct gagggctacc
2461 gcgtcaccta tacccccatg gcacctggca gctacctcat ctccatcaag tacggcggcc
2521 cctaccacat tgggggcagc cccttcaagg ccaaagtcac aggcccccgt ctcgtcagca
2581 accacagcct ccacgagaca tcatcagtgt ttgtagactc tctgaccaag gccacctgtg
2641 ccccccagca tggggccccg ggtcctgggc ctgctgacgc cagcaaggtg gtggccaagg
2701 gcctggggct gagcaaggcc tacgtaggcc agaagagcag cttcacagta gactgcagca
2761 aagcaggcaa caacatgctg ctggtggggg ttcatggccc aaggaccccc tgcgaggaga
2821 tcctggtgaa gcacgtgggc agccggctct acagcgtgtc ctacctgctc aaggacaagg
2881 gggagtacac actggtggtc aaatgggggg acgagcacat cccaggcagc ccctaccgcg
2941 ttgtggtgcc ctgagtctgg ggcccgtgcc agccggcagc ccccaagcct gccccgctac
3001 ccaagcagcc ccgccctctt cccctcaacc ccggcccagg ccgccctggc cgcccgcctg
3061 tcactgcagc cgcccctgcc ctgtgccgtg ctgcgctcac ctgcctcccc agccagccgc
3121 tgacctctcg gctttcactt gggcagaggg agccatttgg tggcgctgct tgtcttcttt
3181 ggttctggga ggggtgaggg atgggggtcc tgtacacaac cacccactag ttctcttctc
3241 cagccaagag gaataaagtt ttgcttccat taaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3301 aaaaaaaaaa aaaaaaaa
//