LOCUS BC066963 2039 bp mRNA linear HUM 19-JUN-2006
DEFINITION Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A
hydratase (trifunctional protein), beta subunit, mRNA (cDNA clone
MGC:87480 IMAGE:4796447), complete cds.
ACCESSION BC066963
VERSION BC066963.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2039)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2039)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 167 Row: c Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4504326.
FEATURES Location/Qualifiers
source 1..2039
/db_xref="H-InvDB:HIT000262383"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:87480 IMAGE:4796447"
/tissue_type="Brain, hypothalamus"
/clone_lib="NIH_MGC_96"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..2039
/gene="HADHB"
/gene_synonym="MGC87480"
/gene_synonym="MSTP029"
/gene_synonym="TP-BETA"
/db_xref="GeneID:3032"
/db_xref="HGNC:HGNC:4803"
/db_xref="MIM:143450"
CDS 85..1512
/gene="HADHB"
/gene_synonym="MGC87480"
/gene_synonym="MSTP029"
/gene_synonym="TP-BETA"
/codon_start=1
/product="hydroxyacyl-Coenzyme A
dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), beta subunit"
/protein_id="AAH66963.1"
/db_xref="GeneID:3032"
/db_xref="HGNC:HGNC:4803"
/db_xref="MIM:143450"
/translation="MTTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTK
KTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYI
IFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDV
IVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEF
STSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTV
TKDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKP
KAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFK
AMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEG
GQYGLVAACAAGGQGHAMIVEAYPK"
BASE COUNT 564 a 436 c 466 g 573 t
ORIGIN
1 cccttggtcc cgcagagcct tggtacttgg acctgaacct tgctccgaga gggagtcctc
61 gcggacgtca gccaagattc cagaatgact actatcttga cttacccctt taaaaatctt
121 cccactgcat caaaatgggc cctcagattt tccataagac ctctgagctg ttcctcccag
181 ctacgagctg ccccagctgt ccagaccaaa acgaagaaga cgttagccaa acccaatata
241 aggaatgttg tggtggtgga tggtgttcgc actccatttt tgctgtctgg cacttcatat
301 aaagacctga tgccacatga tttggctaga gcagcgctta cgggtttgtt gcatcggacc
361 agtgtcccta aggaagtagt tgattatatc atctttggta cagttattca ggaagtgaaa
421 acaagcaatg tggctagaga ggctgccctt ggagctggct tctctgacaa gactcctgct
481 cacactgtca ccatggcttg tatctctgcc aaccaagcca tgaccacagg tgttggcttg
541 attgcttctg gccagtgtga tgtgatcgtg gcaggtggtg ttgagttgat gtccgatgtc
601 cctattcgtc actcaaggaa aatgagaaaa ctgatgcttg atctcaataa ggccaaatct
661 atgggccagc gactgtcttt aatctctaaa ttccgattta atttcctagc acctgagctc
721 cctgcggttt ctgagttctc caccagtgag accatgggcc actctgcaga ccgactggcc
781 gctgcctttg ctgtttctcg gctggaacag gatgaatatg cactgcgctc tcacagtcta
841 gccaagaagg cacaggatga aggactcctt tctgatgtgg tacccttcaa agtaccagga
901 aaagatacag ttaccaaaga taatggcatc cgtccttcct cactggagca gatggccaaa
961 ctaaaacctg cattcatcaa gccctacggc acagtgacag ctgcaaattc ttctttcttg
1021 actgatggtg catctgcaat gttaatcatg gcggaggaaa aggctctggc catgggttat
1081 aagccgaagg catatttgag ggattttatg tatgtgtctc aggatccaaa agatcaacta
1141 ttacttggac caacatatgc tactccaaaa gttctagaaa aggcaggatt gaccatgaat
1201 gatattgatg cttttgaatt tcatgaagct ttctcgggtc agattttggc aaattttaaa
1261 gccatggatt ctgattggtt tgcagaaaac tacatgggta gaaaaaccaa ggttggattg
1321 cctcctttgg agaagtttaa taactggggt ggatctctgt ccctgggaca cccatttgga
1381 gccactggct gcaggttggt catggctgct gccaacagat tacggaaaga aggaggccag
1441 tatggcttag tggctgcgtg tgcagctgga gggcagggcc atgctatgat agtggaagct
1501 tatccaaaat aatagatcca gaagaagtga cctgaagttt ctgtgcaaca ctcacactag
1561 gcaatgccat ttcaatgcat tactaaatga catttgtagt tcctagctcc tcttaggaaa
1621 acagttcttg tggccttcta ttaaatactt tgcacttaag ccttgccagt gttctgagct
1681 tttcaataat cagtttactg ctctttcagg gatttctaag ccaccagaat ctcacatgag
1741 atgtgtgggt ggttgttttt ggtctctgtt gtcactaaag actaaatgag ggtttgcagt
1801 tgggaaagag gtcaactgag atttggaaat catctttgta atatttgcaa attatacttg
1861 ttcttatctg tgtcctaaag atgtgttctc tataaaatac aaaccaacgt gcctaattaa
1921 ttatggaaaa ataattcaga atctaaacac cactgaaaac ttataaaaaa tgtttagata
1981 cataaatatg gtggtcagcg ttaataaagt ggagaaatat tggaaaaaaa aaaaaaaaa
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