LOCUS BC066655 2593 bp mRNA linear HUM 30-MAR-2004
DEFINITION Homo sapiens leucine-rich repeat kinase 1, mRNA (cDNA clone
IMAGE:6165604), partial cds.
ACCESSION BC066655
VERSION BC066655.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2593)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2593)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 140 Row: n Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13375898.
FEATURES Location/Qualifiers
source 1..2593
/db_xref="H-InvDB:HIT000262288"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6165604"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..2593
/gene="LRRK1"
/gene_synonym="FLJ23119"
/gene_synonym="KIAA1790"
/db_xref="GeneID:79705"
CDS <1..1320
/gene="LRRK1"
/gene_synonym="FLJ23119"
/gene_synonym="KIAA1790"
/codon_start=1
/product="LRRK1 protein"
/protein_id="AAH66655.1"
/db_xref="GeneID:79705"
/translation="MCCPGMKVSCQLQVQRSLWTATEDQKIYIYTLKGMCPLNTPQQA
LDTPAVVTCFLAVPVIKKNSYLVLAGLADGLVAVFPVVRGTPKDSCSYLCSHTANRSK
FSIADEDARQNPYPVKAMEVVNSGSEVWYSNGPGLLVIDCASLEICRRLEPYMAPSMV
TSVVCSSEGRGEEVVWCLDDKANSLVMYHSTTYQLCARYFCGVPSPLRDMFPVRPLDT
EPPAASHTANPKVPEGDSIADVSIMYSEELGTQILIHQESLTDYCSMSSYSSSPPRQA
ARSPSSLPSSPASSSSVPFSTDCEDSDMLHTPGAASDRSEHDLTPMDGETFSQHLQAV
KILAVRDLIWVPRRGGDVIVIGLEKDSEAQRGRVIAVLKARELTPHGVLVDAAVVAKD
TVVCTFENENTEWCLAVWRGWGAREFDIFYQSYEELGRLEACTRKRR"
BASE COUNT 598 a 735 c 693 g 567 t
ORIGIN
1 atgtgctgcc ctgggatgaa ggtgagctgc cagctccagg tccagagatc cctgtggaca
61 gccaccgagg accagaaaat ctacatctac accctcaagg gcatgtgccc cttaaacaca
121 ccccaacagg ccttggatac tccagctgtc gtcacctgct tcttggccgt gcctgttatt
181 aaaaagaatt cctacctggt cttagcgggc ctcgccgatg ggcttgtggc tgtgtttccc
241 gtggtgcggg gcaccccaaa ggacagctgc tcctacctgt gctcacacac agccaacagg
301 tccaagttca gcatcgcgga tgaagacgca cggcagaacc cctacccagt gaaggccatg
361 gaggtggtca acagcggctc tgaggtctgg tacagcaatg ggccgggcct ccttgtcatc
421 gactgtgcct ccctggagat ctgcaggcgg ctggagccct acatggcccc ctccatggtt
481 acgtcagtcg tgtgcagctc tgagggcaga ggggaggagg tcgtctggtg cctggatgac
541 aaggccaact ccttggtgat gtaccactcc accacctacc agctgtgtgc ccggtacttc
601 tgcggggtcc ccagccccct cagggacatg tttcccgtgc ggcccttgga cacggaaccc
661 ccggcagcca gccacacggc caacccaaag gtgcctgagg gggactccat cgcggacgtg
721 agcatcatgt acagtgagga gctgggcacg cagatcctga tccaccagga atcactcact
781 gactactgct ccatgtcctc ctactcctca tccccacccc gccaggctgc caggtccccc
841 tcaagcctcc ccagctcccc agcaagttct tccagtgtgc ctttctccac cgactgcgag
901 gactcagaca tgctacatac gcccggtgct gcctccgaca ggtctgagca tgacctgacc
961 cccatggacg gggagacctt cagccagcac ctgcaggccg tgaagatcct cgccgtcaga
1021 gacctcattt gggtccccag gcgcggtgga gatgttatcg tcattggcct ggagaaggat
1081 tctgaagccc agcggggccg agtcattgcc gtcttaaaag cccgagagct gactccgcat
1141 ggggtgctgg tggatgctgc cgtggtggca aaggacactg ttgtgtgcac ctttgaaaat
1201 gaaaacacag agtggtgcct ggccgtctgg aggggctggg gcgccaggga gttcgacatt
1261 ttctaccagt cctacgagga gctgggccgg ctggaggctt gcactcgcaa gagaaggtaa
1321 ttcctgtgga atgactgtca cacatcagag ctggctggcc cggggctgca gcctgacccc
1381 tctgccatcg gcctctagtt ctccaaggac ctagaagaca gatggagttc tcccctgaac
1441 tccttgctgc taagaagtgc tgagaagtta ctcgcctggc ggtggctcca gggttctctg
1501 gttctctgga gcagagttct ctgaataccc catcccccaa ctgctgattt tacagcccca
1561 gggaagacag tggtatcagg ctgggagcgg cctcctctgg cctcccccat cagtttgcag
1621 gagcaggggt gcaggatcct gttctgagct gggtcaaaca aagcagggcc gggccttcct
1681 gccatcccca ggtctcagat ggaattacac tagaggccct ccgctgggaa gcacttgagg
1741 tagggcagga ggggggctgt gacccctgcc ctttccccgc cagagacctc aggctctcag
1801 cacattccac aggctcctga gtccccgagg cctgggccag cttgggcaag ccaagatcag
1861 atgtctctgt gttcgggaag gtctccgtgt gggaaagccc ttgggggatc ccgggtgagg
1921 agtgttgccc catccagaga atgaatgagt tcctttaagt gccaccgcca gcaagcccag
1981 aggcacacag tccgagtgca cccgcttagc ctttacattc ctctccaccg acaaaaggaa
2041 ggggaaactc aatcagcagg acttcagaaa gggccttgtg tttatagctt tgtcaagtaa
2101 atttggacgc agctggagca caggccctgt ttgtttgcac ataataatct tgtttatcac
2161 tttaaaaaat tcagtaatat ctcagcagtc aggcttctgg ttgtgaaatc acattgtatg
2221 ggatttatac caaattatgt atttgctaaa cattcactgc acacgtgtac agcggagtac
2281 gaaaaggaac gttgtccaca ggggatttat ggatacaaca gcaaacattt tataaactat
2341 gcacatgcat tacacacatg cacacacata tgcacacaca tgtgcaaaca tagccacttt
2401 tttgtcaaga gttacccttt ggggctcctt aaaccagaat gggagtttga aagagagatc
2461 atactccagc tgaagtttgt tgaccctttt ctaaaattaa aaagatcaaa tttagtattt
2521 gctggatatg cagggagatg agactctttt aatctcaaaa taaacagatt ctttcaagaa
2581 aaaaaaaaaa aaa
//