LOCUS BC065934 4619 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens WD repeat and FYVE domain containing 1, mRNA (cDNA
clone MGC:70620 IMAGE:6164567), complete cds.
ACCESSION BC065934
VERSION BC065934.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4619)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4619)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-FEB-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 140 Row: n Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 51702527.
FEATURES Location/Qualifiers
source 1..4619
/db_xref="H-InvDB:HIT000262112"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:70620 IMAGE:6164567"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4619
/gene="WDFY1"
/gene_synonym="FENS-1"
/gene_synonym="WDF1"
/gene_synonym="ZFYVE17"
/db_xref="GeneID:57590"
/db_xref="HGNC:HGNC:20451"
CDS 48..1280
/gene="WDFY1"
/gene_synonym="FENS-1"
/gene_synonym="WDF1"
/gene_synonym="ZFYVE17"
/codon_start=1
/product="WD repeat and FYVE domain containing 1"
/protein_id="AAH65934.1"
/db_xref="GeneID:57590"
/db_xref="HGNC:HGNC:20451"
/translation="MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASE
DRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRIFVGQDNGAVMEFHVSEDFN
KMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASC
LQYDFDTQYAFVGDYSGQITLLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGA
SDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVSCSSDGGIAVWNMDVSRE
EAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPV
MGFEFQVRVCDSCYDSIKDEDRTSLATFHEGKHNISHMSMDIARGLMVTCGTDRIVKI
WDMTPVVGCSLATGFSPH"
BASE COUNT 1339 a 895 c 1002 g 1383 t
ORIGIN
1 gctgatgggc tgcctgccga ggaggccgca gcagtcgccg cgcgaacatg gcggccgaaa
61 tccactccag gccgcagagc agccgcccgg tgctgctgag caagatcgag gggcaccagg
121 acgccgtcac ggccgcgctg ctcatcccca aggaggacgg cgtgatcacg gccagcgagg
181 acagaaccat ccgggtatgg ctgaaaagag acagtggtca atactggccc agcatttacc
241 acacaatggc ctctccttgc tctgctatgg cttaccatca tgacagcaga cggatatttg
301 tgggccagga taatggagct gtaatggaat ttcacgtttc tgaagatttt aataaaatga
361 actttatcaa gacctaccca gctcatcaga accgggtgtc tgcgattatc ttcagcttgg
421 ccacagagtg ggtgatcagt accggccacg acaagtgtgt gagctggatg tgcacgcgga
481 gcgggaacat gctcgggagg cacttcttca cgtcctgggc ttcgtgtctg caatatgact
541 ttgacactca gtatgctttc gttggtgatt attctgggca gatcaccctg ctgaagcttg
601 aacagaacac gtgttcagtc atcacaaccc tcaaaggaca tgaaggtagt gtcgcctgcc
661 tctggtggga ccctattcag cggttactct tctcaggagc atctgacaac agcatcatca
721 tgtgggacat cggaggaagg aaaggccgga cgctgttact tcagggccat catgacaagg
781 tgcagtcgct gtgctacctt cagctcacca ggcagctcgt ctcctgttcc tcggacggcg
841 gaattgcagt gtggaacatg gatgttagca gagaagaggc tcctcagtgg ttggaaagtg
901 attcttgtca gaaatgtgag cagccatttt tctggaacat aaagcagatg tgggacacca
961 agacgctggg gctaagacaa catcactgca ggaaatgcgg gcaggctgtc tgcgggaagt
1021 gcagcagcaa gcgctcaagt tacccagtca tgggcttcga gttccaagtc cgggtttgtg
1081 attcttgtta cgactccatc aaagatgaag atcggacttc tctagcgacc tttcatgaag
1141 gaaaacataa catttcccac atgtccatgg acattgccag gggactgatg gtgacctgtg
1201 ggaccgaccg cattgtaaag atctgggaca tgacacctgt ggtgggctgc agtctggcga
1261 ctgggttttc tccgcactga tctgagagct gggcagcgtc cacacctaag aacagcagct
1321 ccaccaaatg aagtccctct cacgcagctc cacagcgctg tctcgtgaat ggacagtagc
1381 cacttacaaa caaatcaaca tttttaaaaa gaaaatgtaa aggtgtgttt tggggcattt
1441 gtggaactta cccatgggga ctaatatgga aaaggtctgt ccatagtggt tccctgaaga
1501 ctggaattac ttcagcaaaa cttccccatg aacagctaat gtgtagtgaa agaatgagct
1561 agcaaatgag ttttagcggg gacaaaaaat caaacaaaaa agtgaatgct tagaaccttc
1621 tcaaagcagt cacaagtaca gacacttcac ttagcctagg gggccttcca gggttcttgt
1681 ggctgttgtc agagcaggag ctgggggagg gaagacttgt tctctctttc ttgaggggtg
1741 gcattaggaa cttacgaaac cagagacctt tccctatgac ttggcagtat gtgaatatcc
1801 tctacactta gttattgata aacttcttaa agagatctgt tattttcagg tagtgccata
1861 atctgcactt agcattggct tgcttcagtt gtttctcttc ccagccagta tgccacaggt
1921 gaactttcga ggttgtcatt aagtaagttg tgaaatttct gtaataacaa aggcagtccg
1981 cattcttccc tttcccccaa attcctaggg caaaactttt ttatggtgct gttaacatgg
2041 gagtcacaca agccgcctga ctttttctca ttgccattag taatgactga tggaaaaccc
2101 agccaccact gtgatgcgaa atgatcagtc tgttgcctga aacagcccag tcctcttaac
2161 tgaaacagca ttctacttct tgttccaaga tgagcctctg caatattctg gcaatttaat
2221 atacccccta caaaagcact ccacagcttt tacactattt tgactttgag ttataactag
2281 tattattcat gttttcataa aaagaagtta gtgacccaga gctataatca tccatcaagt
2341 cttccacaat aattcccaac tcataaattg ctttcctaac aactagcaaa agctattgtt
2401 cataatggca tttctaaagc ttttgggcac tgtgtaccag gatgaggaag agaagaaatg
2461 aggagcctgt cttttaatat tccagtattt gtgtgtttga ttttttttga caacagtaca
2521 tatatctatt tctctaggga tatggaagta agtggagaag ggcctacctt tttaaaggac
2581 aaatataaaa atagcaacag tatctttgct aatcttacta atggatattg attaaaaaaa
2641 aaaaacctca gtactgcatc actgtgttgg gatcgtacca ggacaatagg gtcattccat
2701 atgataaaac taaaggacta aatttgtttt ataatgatgt cttagaggga ctgaaaagtt
2761 taaggaggcg atcaaactaa aatgtcttaa tggctgtgtg acacacgtaa ggaaaggaaa
2821 gggggtcacg cacatcatgt actggaatga tctgcattaa acattgactt gtcttcagaa
2881 ataagactga agggttttgt tgttccttag agttttcgtg ttacatcacc taaagagatt
2941 tcttttaaaa actttctaga ctctttgcaa aatgtatatt actaacatag tttggaagaa
3001 aaattgagta gtggtaagtt ttgttcaagc acaatgttga atgttaagct tcctgtatta
3061 attttagttc agttaatggt tcagcccata caaaggtgct atcctaggga ttttatgaat
3121 tcctgaaagg aaaatagaat atgatcaatt ccttgccctg tggaagagtg cagaactgtg
3181 gttttgtttt cctttgactt ctgtaaaatg tgaccgtttg acatctgtgg tagattgaac
3241 ggaatatcac agctgctgag tttactccat agctttcaaa ccttttttat tttaagaaat
3301 tcttgaaaaa ccctatgttc catgggaaca taaagttatt atagtgcctc ctaaggggtt
3361 aatataaatc aaggaggaag tttatattta aggaagaatt ggagtgacgt atcttagaaa
3421 aggaaaggct gatgtttcca tatagcttgc tctccaccag gcctatcatt tttcttttta
3481 gagacaaacg tgacaggcta gtcttgtctc tctcatatgc taggtagcaa atggggtgat
3541 atttttatag aagtgggcaa aaattatttt ctcaatttta ctgagtaggc acagaagaaa
3601 agtacagata ggctgatggt tattgcctta ttttgactgc atttctctta aatggatcat
3661 ttaaattagt tcttcaagta acagtttact ggttgttcca ttcctgaata tgcaggctaa
3721 tttgtacaga tagggattaa ggaatacaga ctattagaga agatccttat atttacatct
3781 agtatatatg tggtaaggaa atgccgattc ttcattataa acaagtttta aaattgttct
3841 ttcttagttc aaatgatagc aataccccta tagcattagg tagaaacaaa ttattcatta
3901 catcgtaaat ctctttacta tgtcctagct ctgtcctgct acctaaagga tataaagaaa
3961 tattattgct ctagaatgta ttactttgtt ctcccatgaa agaattcagt ttgttagtac
4021 ctatattttt aaactggtga aactgaccca aatatgtaat aaataccata gtagctcaga
4081 cccaaggaga tatttttcta aaatcagttt tcgttaaagt acttctactt ccgttattgg
4141 atatggtatc tcctaaagtg taaaaaaaat ctgttactat atagtgataa accatctgct
4201 catcgtaagt gtaaggctta acaaataagt aatacatgct atatttattc aagtgtctat
4261 tgcttaattg ttaattgtga gcagatttat tgaatgccta ttctattttc tgcagtttac
4321 aatacaataa ctcttagagt aagttgaagt ttaattgtgc aacaaatttg tattagagta
4381 caatttaaag tgtttttctc tatagccttt tttgactggg gaagcaaggg gtaatgttaa
4441 ttagtacact ttgttcttgt actagctatg tttctataag atatggtgcc ctgtgtatcc
4501 cagagatgct agaaaactgt tctttgctcc tatttgtggg ttctgttttt gtgggttttt
4561 ttttttttga gaaaatgtac acaataaaac attccttgct tgttaaaaaa aaaaaaaaa
//