LOCUS BC065832 1078 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens proopiomelanocortin, mRNA (cDNA clone MGC:75488
IMAGE:30392189), complete cds.
ACCESSION BC065832
VERSION BC065832.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1078)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1078)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Michael Brownstein
cDNA Library Preparation: Invitrogen Corp
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 141 Row: p Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4505948.
FEATURES Location/Qualifiers
source 1..1078
/db_xref="H-InvDB:HIT000262072"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75488 IMAGE:30392189"
/tissue_type="Pituitary"
/clone_lib="NIH_MGC_179"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene 1..1078
/gene="POMC"
/gene_synonym="ACTH"
/gene_synonym="CLIP"
/gene_synonym="LPH"
/gene_synonym="MSH"
/gene_synonym="NPP"
/gene_synonym="POC"
/db_xref="GeneID:5443"
/db_xref="HGNC:HGNC:9201"
/db_xref="MIM:176830"
CDS 87..890
/gene="POMC"
/gene_synonym="ACTH"
/gene_synonym="CLIP"
/gene_synonym="LPH"
/gene_synonym="MSH"
/gene_synonym="NPP"
/gene_synonym="POC"
/codon_start=1
/product="POMC protein"
/protein_id="AAH65832.1"
/db_xref="GeneID:5443"
/db_xref="HGNC:HGNC:9201"
/db_xref="MIM:176830"
/translation="MPRSCCSRSGALLLALLLQASMEVRGWCLESSQCQDLTTESNLL
ECIRACKPDLSAETPMFPGNGDEQPLTENPRKYVMGHFRWDRFGRRNSSSSGSSGAGQ
KREDVSAGEDCGPLPEGGPEPRSDGAKPGPREGKRSYSMEHFRWGKPVGKKRRPVKVY
PNGAEDESAEAFPLEFKRELTGQRLREGDGPDGPADDGAGAQADLEHSLLVAAEKKDE
GPYRMEHFRWGSPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAYKKGE"
BASE COUNT 234 a 351 c 345 g 148 t
ORIGIN
1 gcgtccccgc cctcagagag cagcctcccg agacaggggt cccaccaatc ttgtttgctt
61 ctgcagagcc tcagcctgcc tggaagatgc cgagatcgtg ctgcagccgc tcgggggccc
121 tgttgctggc cttgctgctt caggcctcca tggaagtgcg tggctggtgc ctggagagca
181 gccagtgtca ggacctcacc acggaaagca acctgctgga gtgcatccgg gcctgcaagc
241 ccgacctctc ggccgagact cccatgttcc cgggaaatgg cgacgagcag cctctgaccg
301 agaacccccg gaagtacgtc atgggccact tccgctggga ccgattcggc cgccgcaaca
361 gcagcagcag cggcagcagc ggcgcagggc agaagcgcga ggacgtctca gcgggcgaag
421 actgcggccc gctgcctgag ggcggccccg agccccgcag cgatggtgcc aagccgggcc
481 cgcgcgaggg caagcgctcc tactccatgg agcacttccg ctggggcaag ccggtgggca
541 agaagcggcg cccagtgaag gtgtacccta acggcgccga ggacgagtcg gccgaggcct
601 tccccctgga gttcaagagg gagctgactg gccagcgact ccgggaggga gatggccccg
661 acggccctgc cgatgacggc gcaggggccc aggccgacct ggagcacagc ctgctggtgg
721 cggccgagaa gaaggacgag ggcccctaca ggatggagca cttccgctgg ggcagcccgc
781 ccaaggacaa gcgctacggc ggtttcatga cctccgagaa gagccagacg cccctggtga
841 cgctgttcaa aaacgccatc atcaagaacg cctacaagaa gggcgagtga gggcacagcg
901 gggccccagg gctaccctcc cccaggaggt cgaccccaaa gccccttgct ctcccctgcc
961 ctgctgccgc ctcccagcct ggggggtcgt ggcagataat cagcctctta aagctgcctg
1021 tagttaggaa ataaaacctt tcaaatttca aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//