LOCUS BC065278 3331 bp mRNA linear HUM 03-FEB-2004
DEFINITION Homo sapiens DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57, mRNA
(cDNA clone IMAGE:6163491), partial cds.
ACCESSION BC065278
VERSION BC065278.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3331)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3331)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (12-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 140 Row: n Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21717811.
FEATURES Location/Qualifiers
source 1..3331
/db_xref="H-InvDB:HIT000261841"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6163491"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..3331
/gene="DHX57"
/gene_synonym="FLJ32861"
/db_xref="GeneID:90957"
CDS <1..2755
/gene="DHX57"
/gene_synonym="FLJ32861"
/codon_start=2
/product="DHX57 protein"
/protein_id="AAH65278.1"
/db_xref="GeneID:90957"
/translation="EVEKASESEESDEDDGPAPVIVENESYVNLKKKISKRYDWQAKS
VHAENGKICKQFRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGC
GKTTQIPQFILDDSLNGPPEKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQI
RLESVKSSATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDI
VSQRPGLQVILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQD
GSPYMRSMKQISKEKLKARRNRTAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQL
LARYKGVSKSVIKTMSIMDFEKVNLELIEALLEWIVDGKHSYPPGAILVFLPGLAEIK
MLYEQLQSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETS
ITIDDVVYVIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLF
TSHHYNHQLLKQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRA
SKIRLRDLGALTPDERLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAF
KSPFVSPWDKKEEANQKKLEFAFANSDYLALLQAYKGWQLSTKEGVRASYNYCRQNFL
SGRVLQEMASLKRQFTELLSDIGFAREGLRAREIEKRAQGGDGVLDATGEEANSNAEN
PKLISAMLCAALYPNVVQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHPS
SVNYQVRHFDSPYLLYHEKIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRGEFVVS
LDDGWIRFVAASHQVAELVKELRCELDQLLQDKIKNPSIDLCTCPRGSRIISTIVKLV
TTQ"
misc_feature 275..703
/gene="DHX57"
/gene_synonym="FLJ32861"
/note="DEXHc; Region: DEXH-box helicases. A diverse family
of proteins involved in ATP-dependent DNA or RNA
unwinding, needed in a variety of cellular processes. The
name derives from the sequence of the Walker B motif
(motif II). This domain contains the ATP-binding region"
/db_xref="CDD:cd00269"
misc_feature 1241..1498
/gene="DHX57"
/gene_synonym="FLJ32861"
/note="HELICc; Region: helicase superfamily c-terminal
domain"
/db_xref="CDD:smart00490"
misc_feature 1712..1969
/gene="DHX57"
/gene_synonym="FLJ32861"
/note="HA2; Region: Helicase associated domain (HA2). This
presumed domain is about 90 amino acid residues in length.
It is found is a diverse set of RNA helicases. Its
function is unknown, however it seems likely to be
involved in nucleic acid binding"
/db_xref="CDD:pfam04408"
BASE COUNT 1005 a 678 c 766 g 882 t
ORIGIN
1 agaagttgaa aaagcatcag aatctgagga gtcagatgag gatgacggtc ctgcacctgt
61 tatagtagag aatgaaagct atgtgaacct taagaaaaag atttccaaaa gatatgactg
121 gcaggcaaag tcagtacatg ctgaaaatgg taaaatctgc aagcagttcc gaatgaaaca
181 ggcttccaga cagttccagt ccattctgca agagaggcaa tcactccctg cttgggaaga
241 aagagaaacc attcttaact tattgcgtaa gcaccaggtg gttgtcataa gtggtatgac
301 tggatgtggg aaaaccacac aaattccgca gtttattctg gatgattctc tgaatggacc
361 acctgagaag gtagccaaca tcatctgtac ccaaccccga cgaatctctg caatctctgt
421 tgctgaacgc gttgctaaag aaagagcaga gagggtgggt ctgaccgtgg gataccagat
481 tcggttagaa agtgtcaagt cctcagccac cagactgtta tactgcacca cgggagtgct
541 gctgagaagg ctagaaggag atacagctct acaaggagtt tcccatatca ttgttgatga
601 agttcatgag aggacagaag aaagtgactt cttgctgcta gttttgaagg acattgtatc
661 gcagaggcca ggtcttcaag ttattttaat gagtgcaact ctaaacgctg agcttttttc
721 agactatttt aattcctgcc ccgttattac tataccaggt cgtacatttc ctgttgatca
781 attttttttg gaagatgcaa ttgctgtgac aaggtatgta ttacaggatg ggagcccata
841 tatgcggtcc atgaaacaga tttcaaagga aaagcttaaa gcaaggcgga acagaactgc
901 atttgaagaa gtggaagaag acctaaggct ctcccttcac ctccaggatc aggattctgt
961 caaagatgca gtgccagatc aacagttaga ttttaagcag ctcctggccc gctataaagg
1021 ggttagcaag tcagtcatca aaacaatgtc catcatggat tttgaaaagg tgaatcttga
1081 attaatagag gccttattag agtggattgt ggatggaaag cactcctacc ctccaggtgc
1141 tatacttgta tttttaccag gactagcaga aatcaaaatg ctttatgaac agctacagtc
1201 taattctctt ttcaacaaca gacgtagtaa tcgatgtgtt attcacccac ttcattcatc
1261 tttatccagt gaagagcagc aggctgtgtt tgtaaaacct cctgcaggag taactaagat
1321 tataatttcc accaacattg ctgagacatc cataaccatc gatgatgttg tctatgttat
1381 cgattctggg aaaatgaaag aaaagagata tgatgccagc aaagggatgg aaagtctaga
1441 ggacaccttt gtatctcaag ctaatgctct acaaaggaaa ggccgagcag gccgtgttgc
1501 atctggggtc tgcttccatt tattcactag ccatcactac aatcaccagc ttttaaaaca
1561 acagctacca gaaatacaaa gagtgccatt ggaacagctg tgtctaagaa ttaaaatttt
1621 agagatgttt agtgctcata atctccagtc tgtgttctct cggctcattg aacctccaca
1681 caccgattct cttcgtgcct caaaaatacg attacgagac ttaggagcat taactccaga
1741 tgaaagattg acccctcttg ggtatcattt ggcctctctg cccgtggatg tgagaattgg
1801 caaactaatg ttgtttgggt ctatcttccg ctgtttggat cctgctctca ccattgctgc
1861 cagtttggct tttaagtctc cgtttgtatc tccctgggat aaaaaagaag aagctaacca
1921 gaaaaagctg gaatttgcat tcgcaaacag tgattatctg gcccttctac aagcgtataa
1981 gggatggcag ctaagtacaa aagaaggcgt gcgtgcaagt tataattact gcagacaaaa
2041 cttcttgtct ggaagagttc tgcaggaaat ggccagcctc aaacgacaat tcacggaact
2101 gttatcggat atagggtttg caagggaagg gctcagagca agggaaattg agaaaagggc
2161 ccaaggagga gatggtgtct tagatgccac aggagaagag gcaaactcaa atgctgagaa
2221 ccccaagctg atatcagcaa tgctgtgtgc tgctttgtat ccaaatgtag tgcaggtgaa
2281 aagcccagaa ggaaaatttc agaagaccag tactggagct gtcagaatgc aaccaaaatc
2341 agctgagttg aagtttgtca ccaagaacga tggatatgta cacattcacc cttcatcagt
2401 gaactatcag gtgagacact ttgacagccc ctacctgttg taccacgaga agataaaaac
2461 tagtcgagta ttcatccgag actgcagcat ggtgtctgtg tacccgctgg tcttgtttgg
2521 aggaggccaa gtgaatgtgc agcttcaaag aggagagttc gttgtctccc tggatgatgg
2581 ttggatccgt tttgtagctg cttcccatca ggtggctgaa ctggtaaagg agcttcgttg
2641 cgaacttgat cagcttctcc aggataaaat taaaaaccca agcattgatc tgtgtacgtg
2701 tcctcgagga tcccggatca tcagcacaat tgtgaaactt gtcaccacac aataaaaagc
2761 agtcttagag agtgcttgct actcacctgc ttctagctca cctgggaaat aacagcagaa
2821 cctctacctc gaactaaaga cctattgggg ctggccctgg tggaggagcc cagggcatga
2881 agcccaaggc agctgaggca gtgtatatac ccttagggcc atttctaaca aagccttggc
2941 cactcccagc acaatttgga gtgtcaaggg tgagagccta aaacccagct tgcctgtctt
3001 tgtctctgtg attgttctgg agtgaattaa gttcacctga taactcaaaa gtgaatgtat
3061 aatacaattc tgttttaatc tgtgtattct ttttctccta ctttttactg gggtgagagg
3121 ggcatgaaga gaaatacgcc tttttttttt cttttcctgt cgccaaggct cgactgagag
3181 aagtcagaac agagaagggg aaaaaaaacc caaaattatg tgaacaagca aaattaaaat
3241 ttcattttag gctattggct actgagtaaa cttgacttgt gaggggtttt tatttttact
3301 cattaaaagt caacttaaaa aaaaaaaaaa a
//