LOCUS BC065007 2619 bp mRNA linear HUM 06-JAN-2004
DEFINITION Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 6, mRNA (cDNA
clone MGC:74611 IMAGE:6163439), complete cds.
ACCESSION BC065007
VERSION BC065007.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2619)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2619)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 140 Row: m Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21536329.
FEATURES Location/Qualifiers
source 1..2619
/db_xref="H-InvDB:HIT000261711"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:74611 IMAGE:6163439"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_72"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2619
/gene="DDX6"
/gene_synonym="HLR2"
/gene_synonym="P54"
/gene_synonym="RCK"
/db_xref="GeneID:1656"
/db_xref="MIM:600326"
CDS 293..1744
/gene="DDX6"
/gene_synonym="HLR2"
/gene_synonym="P54"
/gene_synonym="RCK"
/codon_start=1
/product="DDX6 protein"
/protein_id="AAH65007.1"
/db_xref="GeneID:1656"
/db_xref="MIM:600326"
/translation="MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQ
LKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYC
LKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDL
KKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHV
VIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLY
SATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQI
NQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD
LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIE
EQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEKP"
misc_feature 584..1189
/gene="DDX6"
/gene_synonym="HLR2"
/gene_synonym="P54"
/gene_synonym="RCK"
/note="DEADc; Region: DEAD-box helicases. A diverse family
of proteins involved in ATP-dependent RNA unwinding,
needed in a variety of cellular processes including
splicing, ribosome biogenesis and RNA degradation. The
name derives from the sequence of the Walker B motif
(motif II). This domain contains the ATP- binding region"
/db_xref="CDD:cd00268"
BASE COUNT 844 a 499 c 547 g 729 t
ORIGIN
1 acgggcccga gtcgcgaggc ttgggattga cgtgagtgaa ttcagatata actcaagctt
61 gttagagggc tttttaaaaa taaaaagttg attccgtgca agagagcaag ttactgctgc
121 ttaccgttca gagacttaca ggtgcttgcc tgcattgcaa taaaggactc atttattgag
181 caagacttat atttatctct tcattttgga gagcctaata aactgttatt acagtttctc
241 tactgacttt caaaagtttt gaagtttgaa agacctttgc aattaaaaca gcatgagcac
301 ggccagaaca gagaaccctg ttataatggg tctgtccagt caaaatggtc agctgagagg
361 ccctgtgaaa cccactggtg gccctggagg agggggcaca cagacacagc aacagatgaa
421 ccagctgaaa aacaccaaca caatcaataa tggcactcag cagcaagcac agagtatgac
481 caccactatt aaacctggtg atgactggaa aaagacttta aaactccctc caaaggatct
541 aagaatcaaa acttcggatg tgacctccac aaaaggaaat gagtttgaag attactgttt
601 gaaacgggag ttactgatgg gaatttttga aatgggctgg gaaaagccat ctcctattca
661 ggaggagagc attcccattg ctttatctgg tagggatatc ttagctagag caaaaaatgg
721 aacaggcaag agcggtgcct acctcattcc cttacttgaa cggctagacc tgaagaagga
781 caatatacaa gcaatggtga ttgttcccac tagagaactt gctctacagg tcagtcaaat
841 ttgcatccag gtcagcaaac acatgggagg ggccaaagtg atggcaacca caggaggaac
901 caatttacga gatgacataa tgaggcttga tgatacagtg cacgtggtga ttgctacccc
961 tgggagaatc ctggatctta ttaagaaagg agtagcaaag gttgatcatg tccagatgat
1021 agtattggat gaggcagata agttgctgtc acaggatttt gtgcagataa tggaggatat
1081 tattctcacg ctacctaaaa acaggcagat tttactatat tccgctactt tccctcttag
1141 tgtacagaag ttcatgaatt cccatttgca gaaaccctat gagattaacc tgatggagga
1201 actaactctg aagggagtaa cccagtacta cgcatatgta actgagcgcc aaaaagtaca
1261 ctgcctcaac acacttttct ccaggcttca gataaaccag tcgatcattt tctgtaactc
1321 ctctcagcga gttgaattgc tagccaagaa gatttctcaa ctgggttatt cttgcttcta
1381 tattcatgct aaaatgaggc aggaacatcg aaatcgtgta tttcatgatt tccgaaatgg
1441 cttatgccgc aatcttgttt gcactgatct gtttacccga ggtattgata tacaagctgt
1501 gaatgtggta ataaactttg atttcccaaa gctggcagag acctatctcc atcgtattgg
1561 aagatcaggt cgctttggtc atcttggctt agccatcaac ttgatcacat atgatgatcg
1621 cttcaacctg aaaagtattg aggagcagct gggaacagaa attaaaccta ttccgagcaa
1681 cattgataag agcctgtatg tggcagaata ccacagcgag cctgtagaag atgagaaacc
1741 ttaacaagca tgctttgaca aattacaaaa ggctcgtttg gatctgtgac acatcgtttt
1801 ggggggaatg ctcttctctt tgtgggtttt tcatctttta ttttggaact atgaagactt
1861 aaaagagctc agacattttc tttttttaac tggtgaagag aaaaaggctg aaaagaagga
1921 atataccttt tttgttccac ttgtttgcac tgtgtgctga ctgaacatta gttgcactaa
1981 ctgctggttt ttaaaaaatg ttttctgggg aaaggggaca aggaaggaaa agaaagaaga
2041 gaaggggaga aaccctaaaa agagaagaat cttaatgaac acacaagctt gtcaatgatt
2101 tcaaaattct ccaacagctg actctcgtgc atttcaactt ctccctgatt cctcatccgt
2161 tttttaagcc tgaagagctt attacttatt tgtgcgaagt gccttatgct atgagaccat
2221 tcagaatatc atcttttaga cacagcccga ggaatcaaca atagtaactc tttctttccg
2281 ttttttttct ttttctttta aaaaatgtct ttttattttg gtttcaggtt gaagtctctt
2341 ccctttctac ccagtactcg agcccagggc tagaagttga aactcactag taatgttaaa
2401 caccattttt tttttctttt tggggaggag ttgatatgca actgcagttc atccgcactg
2461 taaatacatg tatttaaaaa aacaatccca agtaaaaatt tcttctgggc tgagttcttc
2521 tgtaaagaga tgaacgcaat gccaataaaa ttgaacaaga acaatgataa aaaaaaaaaa
2581 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//