LOCUS BC064848 3413 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens GRB2-associated binding protein 1, mRNA (cDNA clone
MGC:75491 IMAGE:30386955), complete cds.
ACCESSION BC064848
VERSION BC064848.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3413)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3413)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Michael Brownstein
cDNA Library Preparation: Invitrogen Corp
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 141 Row: n Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 46370072.
FEATURES Location/Qualifiers
source 1..3413
/db_xref="H-InvDB:HIT000261605"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75491 IMAGE:30386955"
/tissue_type="Testis"
/clone_lib="NIH_MGC_180"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene 1..3413
/gene="GAB1"
/db_xref="GeneID:2549"
/db_xref="HGNC:HGNC:4066"
/db_xref="MIM:604439"
CDS 224..2398
/gene="GAB1"
/codon_start=1
/product="GRB2-associated binding protein 1"
/protein_id="AAH64848.1"
/db_xref="GeneID:2549"
/db_xref="HGNC:HGNC:4066"
/db_xref="MIM:604439"
/translation="MSGGEVVCSGWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDV
LEYYKNDHAKKPIRIIDLNLCQQVDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEE
EMNKWVRCICDICGFNPTEEDPVKPPGSSLQAPADLPLAINTAPPSTQADSSSATLPP
PYQLINVPPHLETLGIQEDPQDYLLLINCQSKKPEPTRTHADSAKSTSSETDCNDNVP
SHKNPASSQSKHGMNGFFQQQMIYDSPPSRAPSASVDSSLYNLPRSYSHDVLPKVSPS
STEADGELYVFNTPSGTSSVETQMRHVSISYDIPPTPGNTYQIPRTFPEGTLGQTSKL
DTIPDIPPPRPPKPHPAHDRSPVETCSIPRTASDTDSSYCIPTAGMSPSRSNTISTVD
LNKLRKDASSQDCYDIPRAFPSDRSSSLEGFHNHFKVKNVLTVGSVSSEELDENYVPM
NPNSPPRQHSSSFTEPIQEANYVPMTPGTFDFSSFGMQVPPPAHMGFRSSPKTPPRRP
VPVADCEPPPVDRNLKPDRKGQSPKILRLKPHGLERTDSQTIGDFATRRKVKPAPLEI
KPLPEWEELQAPVRSPITRSFARDSSRFPMSPRPDSVHSTTSSSDSHDSEENYVPMNP
NLSSEDPNLFGSNSLDGGSSPMIKPKGDKQVEYLDLDLDSGKSTPPRKQKSSGSGSSV
ADERVDYVVVDQQKTLALKSTREAWTDGRQSTESETPAKSVK"
BASE COUNT 1049 a 765 c 702 g 897 t
ORIGIN
1 gctgctgagg cagctggcgt tctgttcagg ttcgtgggcc tgcagaggag agactcgaac
61 tcgtggaacc cgcgcaccgt ggagtctgtc cgcccagtcc gtccggggtg cgcgaccagg
121 agagctaggt tctcgccact gcgcgctcgg caggcgtcgg ctgtgtcggg agcgcgcccg
181 ccgcccctca gctgcccggc ccggagcccg agacgcgcgc accatgagcg gtggtgaagt
241 ggtctgctcc ggatggctcc gcaagtcccc cccggagaaa aagttgaagc gttatgcatg
301 gaagaggaga tggttcgtgt tacgcagtgg ccgtttaact ggagatccag atgttttgga
361 atattacaaa aatgatcatg ccaagaagcc tattcgtatt attgatttaa atttatgtca
421 acaagtagat gctggattga catttaacaa aaaagagttt gaaaacagct acatttttga
481 tatcaacact attgaccgga ttttctactt ggtagcagac agcgaggagg agatgaataa
541 gtgggttcgt tgtatttgtg acatctgtgg gtttaatcca acagaagaag atcctgtgaa
601 gccacctggc agctctttac aagcaccagc tgatttacct ttagctataa atacagcacc
661 accatccacc caggcagatt catcctctgc tactctacct cctccatatc agctaatcaa
721 tgttccacca cacctggaaa ctcttggcat tcaggaggat cctcaagact acctgttgct
781 catcaactgt caaagcaaga agcccgaacc caccagaacg catgctgatt ctgcaaaatc
841 cacctcttct gaaacagact gcaatgataa cgtcccttct cataaaaatc ctgcttcctc
901 ccagagcaaa catggaatga atggcttttt tcagcagcaa atgatatacg actctccacc
961 ttcacgtgcc ccatctgctt cagttgactc cagcctttat aacctgccca ggagttattc
1021 ccatgatgtt ttaccaaagg tgtctccatc aagtactgaa gcagatggag aactctatgt
1081 ttttaatacc ccatctggga catcgagtgt agagactcaa atgaggcatg tatctattag
1141 ttatgacatt cctccaacac ctggtaatac ttatcagatt ccacgaacat ttccagaagg
1201 aaccttggga cagacatcaa agctagacac tattccagat attcctccac ctcggccacc
1261 gaaaccacat ccagctcatg accgatctcc tgtggaaacg tgtagtatcc cacgcaccgc
1321 ctcagacact gacagtagtt actgtatccc tacagcaggg atgtcgcctt cacgtagtaa
1381 taccatttcc actgtggatt taaacaaatt gcgaaaagat gctagttctc aagactgcta
1441 tgatattcca cgagcatttc caagtgatag atctagttca cttgaaggct tccataacca
1501 ctttaaagtc aaaaatgtgt tgacagtggg aagtgtttca agtgaagaac tggatgaaaa
1561 ttacgtccca atgaatccca attcaccacc acgacaacat tccagcagtt ttacagaacc
1621 aattcaggaa gcaaattatg tgccaatgac tccaggaaca tttgattttt cctcatttgg
1681 aatgcaagtt cctcctcctg ctcatatggg cttcaggtcc agcccaaaaa cccctcccag
1741 aaggccagtt cctgttgcag actgtgaacc accccccgtg gataggaacc tcaagccaga
1801 cagaaaaggt caaagtccta aaattttaag actcaaaccc catggtttag agcgaactga
1861 ttcacaaacc ataggtgact ttgctacaag aagaaaggtc aagccagcgc ctttagaaat
1921 aaaacctttg ccagaatggg aagaattaca agccccagtt agatctccca tcactaggag
1981 ttttgctcga gactcttcca ggtttcccat gtccccccga ccagattcag tgcatagcac
2041 aacttcaagc agtgactcac acgacagtga agagaattat gttcccatga acccaaacct
2101 gtccagtgaa gacccaaatc tctttggcag taacagtctt gatggaggaa gcagccctat
2161 gatcaagccc aaaggagaca aacaggtgga atacttagat ctcgacttag attctgggaa
2221 atccacacca ccacgtaagc aaaagagcag tggctcaggc agcagtgtag cagatgagag
2281 agtggattat gttgttgttg accaacagaa gaccttggct ctaaagagta cccgggaagc
2341 ctggacagat gggagacagt ccacagaatc agaaacgcca gcgaagagtg tgaaatgaaa
2401 atattgcctt gccatttctg aacaaaagaa aactgaattg taaagataaa tcccttttga
2461 agaatgactt gacacttcca ctctaggtag atcctcaaat gagtagagtt gaagtcaaag
2521 gacctttctg acataatcaa gcaatttaga cttaagtggt gctttgtggt atctgaacaa
2581 ttcataacat gtaaataatg tgggaaaata gtattgttta gctcccagag aaacatttgt
2641 tccacagtta acacactcgt agtattactg tatttatgca ctttttcatc taaaacattg
2701 ttctgggttt tcccaatgta ccttaccata attcctttgg gagttcttgt tttttgtcac
2761 actactttat ataacaatac taagtcaact aagctacttt tagatttgga aattgctgtt
2821 tacagtctaa caacattaaa atgagaggta gattcacaag ttagctttct acctgaagct
2881 tcaggtgata accattagct tatacttgga ctcatcattt gttgccttcc aaaatgctga
2941 ggataatgta tgtactggtg tcaggaccta gttctctggt taatgtacat ttagttttta
3001 atggtggaac tttgttatat tttgttaatt acagtgtttt tggttcattg agtgaagatt
3061 ctgccgggtg ggatcttgca cctttgaaag actgaataat tacactacca agtaagcctg
3121 caaatcattg atggcatgca gtgatgatgt gctcttacac ttgttaacat gtattaagtg
3181 ttatttgcaa aaggtagatt atgtaaccaa tcaggtacgt accaggcagt gatgtgctaa
3241 tacactgatc aggtttagac aatgagcttt ggttgtgttc ttgttagtcc taatattggt
3301 tttcagtttg gaattaataa agcagttgac attcaaaaaa aaaaaaaaaa aaaaaaaaaa
3361 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//