LOCUS BC064637 2620 bp mRNA linear HUM 01-FEB-2005
DEFINITION Homo sapiens inducible T-cell co-stimulator ligand, mRNA (cDNA
clone MGC:70380 IMAGE:5758883), complete cds.
ACCESSION BC064637
VERSION BC064637.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2620)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2620)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (22-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 139 Row: n Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 46255054.
FEATURES Location/Qualifiers
source 1..2620
/db_xref="H-InvDB:HIT000261556"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:70380 IMAGE:5758883"
/tissue_type="Colon, Kidney, Stomach, adult, whole pooled"
/clone_lib="NIH_MGC_116"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2620
/gene="ICOSLG"
/gene_synonym="B7-H2"
/gene_synonym="B7H2"
/gene_synonym="B7RP-1"
/gene_synonym="B7RP1"
/gene_synonym="GL50"
/gene_synonym="ICOS-L"
/gene_synonym="ICOSL"
/gene_synonym="KIAA0653"
/gene_synonym="LICOS"
/db_xref="GeneID:23308"
/db_xref="MIM:605717"
CDS 109..1017
/gene="ICOSLG"
/gene_synonym="B7-H2"
/gene_synonym="B7H2"
/gene_synonym="B7RP-1"
/gene_synonym="B7RP1"
/gene_synonym="GL50"
/gene_synonym="ICOS-L"
/gene_synonym="ICOSL"
/gene_synonym="KIAA0653"
/gene_synonym="LICOS"
/codon_start=1
/product="ICOSLG protein"
/protein_id="AAH64637.1"
/db_xref="GeneID:23308"
/db_xref="MIM:605717"
/translation="MRLGSPGLLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSR
FDLNDVYVYWQTSESKTVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFN
VTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTS
INGYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIE
NVLLQQNLTVGSQTGNDIGERDKITENPVSTGEKNAATWSILAVLCLLVVVAVAIGWV
CRDRCLQHSYAGAWAVSPETELTGHV"
BASE COUNT 606 a 786 c 750 g 478 t
ORIGIN
1 ccgcgccccg aggttgctcc tctccgaggt ctcccgcggc ccaagttctc cgcgccccga
61 ggtctccgcg ccccgaggtc tccgcggccc gaggtctccg cccgcaccat gcggctgggc
121 agtcctggac tgctcttcct gctcttcagc agccttcgag ctgatactca ggagaaggaa
181 gtcagagcga tggtaggcag cgacgtggag ctcagctgcg cttgccctga aggaagccgt
241 tttgatttaa atgatgttta cgtatattgg caaaccagtg agtcgaaaac cgtggtgacc
301 taccacatcc cacagaacag ctccttggaa aacgtggaca gccgctaccg gaaccgagcc
361 ctgatgtcac cggccggcat gctgcggggc gacttctccc tgcgcttgtt caacgtcacc
421 ccccaggacg agcagaagtt tcactgcctg gtgttgagcc aatccctggg attccaggag
481 gttttgagcg ttgaggttac actgcatgtg gcagcaaact tcagcgtgcc cgtcgtcagc
541 gccccccaca gcccctccca ggatgagctc accttcacgt gtacatccat aaacggctac
601 cccaggccca acgtgtactg gatcaataag acggacaaca gcctgctgga ccaggctctg
661 cagaatgaca ccgtcttctt gaacatgcgg ggcttgtatg acgtggtcag cgtgctgagg
721 atcgcacgga cccccagcgt gaacattggc tgctgcatag agaacgtgct tctgcagcag
781 aacctgactg tcggcagcca gacaggaaat gacatcggag agagagacaa gatcacagag
841 aatccagtca gtaccggcga gaaaaacgcg gccacgtgga gcatcctggc tgtcctgtgc
901 ctgcttgtgg tcgtggcggt ggccataggc tgggtgtgca gggaccgatg cctccaacac
961 agctatgcag gtgcctgggc tgtgagtccg gagacagagc tcactggcca cgtttgaccg
1021 gagctcaccg cccagagcgt ggacagggct tccgtgagac gccaccgtga gaggccaggt
1081 ggcagcttga gcatggactc ccagactgca ggggagcact tggggcagcc cccagaagga
1141 ccactgctgg atcccaggga gaacctgctg gcgttggctg tgatcctgga atgaggccct
1201 ttcaaaagcg tcatccacac caaaggcaaa tgtccccaag tgagtgggct ccccgctgtc
1261 actgccagtc acccacagga agggactggt gatgggctgt ctctacccgg agcgtgcggg
1321 attcagcacc aggctcttcc cagtacccca gacccactgt gggtcttccc gtgggatgcg
1381 ggatcctgag accgaagggt gtttggttta aaaagaagac tgggcgtccg ctcttccagg
1441 acggcgtctg tgctgctggg gtcacgcgag gctgtttgca ggggacacgg tcacaggagc
1501 tcttctgccc tgaacgctcc caacctgcct cccgcccgga agccacagga cccactcatg
1561 tgtgtgccca caagtgtagt tagccgtcca caccgaggag cccccggaag tccccactgg
1621 gcttcagtgt cctctgccac attccctggg aggaacaatg tccctcggct gttccggtga
1681 aaagttgagc cacctttgga agacgcacgg gtggagtttg ccagaagaaa ggctgtgcca
1741 gggccgtgtt tggctacagg ggctgccggg gctcttggct ctgcagcgag aaagacacag
1801 cccagcaggg ctggagacgc ccatgtccag caggcgcagg cctggcaaca cggtccccag
1861 agtcctgagc agcagttagg tgcatggaga gggtatcacc tggtggccac agtccccctt
1921 ctcacctcag caatgatccc caaagtgaga ggtggctccc ccggccccca ccaccctcag
1981 cagccccacc ccactcaacc ctgagggtcc ccagggtcct gatgaagacc tccgacccca
2041 gcgccaggct cctcggagcc caacagtccc aagggggcag tgttgagggg tacagccctg
2101 ggccctgacc agccccggca cctgccatgc tggttcccgg aatgaatcag ctgctgactg
2161 tctccagaag ggctggaaag gatgctgcca ggtgacccga ggtgcactcg ccccagggag
2221 atggagtaga cagcctggcc tggccctcgg gacacattgt ctgccccggg actatgggca
2281 aatgcccctc cttcttactt cccagaatcc cctgacattc ccagggtcag ccaggacctg
2341 ttacagccct ggtcacttgg aactgacagc tgtgtgaggc ctgcacttct cagacccaga
2401 cttagaacaa aaggaggagt gaggactcaa ggctacaatg aggttccagt acttgttaca
2461 agaaattggt tttctgcaaa aaaagtccct acctgggcct ttaggtgaat gtgggatcca
2521 ctcccgcttt taacatgaaa gcattagaag aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2581 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//