LOCUS BC064595 2353 bp mRNA linear HUM 02-JAN-2004
DEFINITION Homo sapiens cDNA clone IMAGE:5755761, partial cds.
ACCESSION BC064595
VERSION BC064595.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2353)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2353)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (22-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 139 Row: n Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 25952081.
FEATURES Location/Qualifiers
source 1..2353
/db_xref="H-InvDB:HIT000261514"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5755761"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
CDS <1..1675
/codon_start=2
/product="Unknown (protein for IMAGE:5755761)"
/protein_id="AAH64595.1"
/translation="RAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDHLL
EPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPID
IFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGI
AIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDP
FFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQG
NGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVI
LFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAG
VLTIALPVPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSK
SEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV"
misc_feature 260..550
/note="K_tetra; Region: K+ channel tetramerisation domain.
The N-terminal, cytoplasmic tetramerisation domain (T1) of
voltage-gated K+ channels encodes molecular determinants
for subfamily-specific assembly of alpha-subunits into
functional tetrameric channels. It is distantly related to
the BTB/POZ domain pfam00651"
/db_xref="CDD:pfam02214"
misc_feature 827..1384
/note="ion_trans; Region: Ion transport protein. This
family contains Sodium, Potassium, Calcium ion channels.
This family is 6 transmembrane helices in which the last
two helices flank a loop which determines ion selectivity.
In some sub-families (e.g. Na channels) the domain is
repeated four times, whereas in others (e.g. K channels)
the protein forms as a tetramer in the membrane. A
bacterial structure of the protein is known for the last
two helices but is not the Pfam family due to it lacking
the first four helices"
/db_xref="CDD:pfam00520"
BASE COUNT 538 a 679 c 598 g 538 t
ORIGIN
1 ccgcgcccac cctcctcagc gcccagcgag cagcggcggt gcccacacgc tggtgaacca
61 cggctacgcg gagcccgccg caggccgcga gctgccgccc gacatgaccg tggtgcccgg
121 ggaccacctg ctggagccgg aggtggccga tggtggaggg gccccgcctc aaggcggctg
181 tggcggcggc ggctgcgacc gctacgagcc gctgccgccc tcactgccgg ccgcgggcga
241 gcaggactgc tgcggggagc gcgtggtcat caacatctcc gggctgcgct tcgagacgca
301 gctgaagacc ctttgccagt tccccgagac gctgctgggc gaccccaagc ggcgcatgag
361 gtacttcgac ccgctccgca acgagtactt cttcgaccgc aaccggccca gcttcgacgc
421 catcctctac tactatcagt ccgggggccg catccgccgg ccggtcaacg tgcccatcga
481 cattttctcc gaggagatcc gcttctacca gctgggcgag gaggccatgg agaagttccg
541 cgaggacgag ggcttcctgc gggaggagga gcggcccttg ccccgccgcg acttccagcg
601 ccaggtgtgg ctgctcttcg agtaccccga gagctccggg ccggcccggg gcatcgccat
661 cgtgtccgtg ctggtcatcc tcatctccat tgtcatcttc tgcctggaga cgctgccgga
721 gttccgcgac gagaaggact accccgcctc gacgtcgcag gactcattcg aagcagccgg
781 caacagcacg tcggggtccc gcgcaggagc ctccagcttc tccgatccct tcttcgtggt
841 ggagacgctg tgcatcatct ggttctcctt cgaactgctg gtgcggttct tcgcttgtcc
901 tagcaaagcc accttctcgc gaaacatcat gaacctgatc gacattgtgg ccatcattcc
961 ttattttatc actctgggta ccgagctggc cgaacgacag ggcaatggac agcaggccat
1021 gtctctggcc atcctgaggg tcatccgcct ggtaagggtc ttccgcatct tcaagctgtc
1081 gcgccactcc aaggggctgc agatcctcgg gcaaacgctg aaggcgtcca tgcgggagct
1141 gggattgctc atcttcttcc tctttattgg ggtcatcctt ttctccagcg cggtctactt
1201 tgccgaggca gacgacccca cttcaggttt cagcagcatc ccggatgcct tctggtgggc
1261 agtggtaacc atgacaacag tgggttacgg cgatatgcac ccagtgacca tagggggcaa
1321 gattgtggga tctctctgtg ccatcgccgg tgtcttgacc atcgcattgc cagttcccgt
1381 gattgtttcc aacttcaatt acttctacca ccgggagaca gaaggggaag agcaatccca
1441 gtacatgcac gtgggaagtt gccagcacct ctcctcttca gccgaggagc tccgaaaagc
1501 aaggagtaac tcgactctga gtaagtcgga gtatatggtg atcgaagagg ggggtatgaa
1561 ccatagcgct ttcccccaga cccctttcaa aacgggcaat tccactgcca cctgcaccac
1621 gaacaataat cccaactctt gtgtcaacat caaaaagata ttcaccgatg tttaatatgt
1681 gatacaagtg acatgctgtg ctcagtattg tgtggaacgt gcccccttgg tctgcctatg
1741 cccttgtttt atacatttcc agaccattca tcaaggaaag gacctgaaga agtggaaagc
1801 acacttcatt ctccctctcc ctgctgcttc atactgaaac aggtgcctgt tttgcaagtg
1861 ggctgcattc tctcagctct ccttttccct cttaccctct ctctctgaac attgtaaaca
1921 acagacttac gttaaacttc atttctagta cacgccctat ttaaaaaaga gcagtacatc
1981 ctgggaggaa atgaaactaa agaacagtta gagtaactgt ttaacctcag aattttaaag
2041 gcagttgttt ctttcctaag cacatcaatt cgtagtaaat gatgcttcgg tttgatggac
2101 ctttcaacgt tatttattga atatgtattt cggttgccta ccctgtagat atgtggatga
2161 agagtctaac tagaataatg acttgtaaac ccaccatgag ttatttggtt tttgacttaa
2221 attcctattt gaatcccctt tcccggaatt ttaagtgtct ctacaacttt gaataaaggg
2281 aaatgcccaa gatgtcctga aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2341 aaaaaaaaaa aaa
//