LOCUS BC064503 2297 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens G protein pathway suppressor 1, mRNA (cDNA clone
MGC:71287 IMAGE:6572943), complete cds.
ACCESSION BC064503
VERSION BC064503.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2297)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2297)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 50 Row: n Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 47078237.
FEATURES Location/Qualifiers
source 1..2297
/db_xref="H-InvDB:HIT000261423"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71287 IMAGE:6572943"
/tissue_type="Prostate, carcinoma"
/clone_lib="NIH_MGC_40"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2297
/gene="GPS1"
/gene_synonym="COPS1"
/gene_synonym="CSN1"
/gene_synonym="MGC71287"
/db_xref="GeneID:2873"
/db_xref="HGNC:HGNC:4549"
/db_xref="MIM:601934"
CDS 355..1938
/gene="GPS1"
/gene_synonym="COPS1"
/gene_synonym="CSN1"
/gene_synonym="MGC71287"
/codon_start=1
/product="G protein pathway suppressor 1"
/protein_id="AAH64503.1"
/db_xref="GeneID:2873"
/db_xref="HGNC:HGNC:4549"
/db_xref="MIM:601934"
/translation="MRDSSAPSSASSSVTDLYCTPHSSRSDLVLPGTAGDFSLSASLS
ACTLLYEGAVEPMQIDVDPQEDPQNAPDVNYVVENPSLDLEQYAASYSGLMRIERLQF
IADHCPTLRVEALKMALSFVQRTFNVDMYEEIHRKLSEATRELQNAPDAIPESGVEPP
ALDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNAL
KCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDS
QTQAILTKLKCAAGLAELAARKYKQAAKCLLLASFDHCDFPELLSPSNVAIYGGLCAL
ATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDM
YLAPHVRTLYTQIRNRALIQYFSPYVSADMHRMAAAFNTTVAALEDELTQLILEGLIS
ARVDSHSKILYARDVDQRSTTFEKSLLMGKEFQRRAKAMMLRAAVLRNQIHVKSPPRE
GSQGELTPANSQSRMSTNM"
BASE COUNT 455 a 767 c 699 g 376 t
ORIGIN
1 cgaggcttgc aggtaacgag ccgaggccgc cccgggcctc cgcgcccccg cgccccccgc
61 cactggggcc gggctgaggt cgagcagggg cgcggggcct gcgccaggag tcggtcgggc
121 acgctccgtg ccgggcctcc gcgggcagcg cgcgtcgggg gctgcagggc cgagggcgcg
181 tctccgccgt ggctgcgcgc tgcgatcggg ggccgccggg ccgcgcccgc cccgcctccc
241 ctcccagcag ctcacgggag aggttcccgg ccgccccgac gctaacgctc tttctccctt
301 cagcagccag ccagctctgt gtcagggtcg gggggtgcag aaagtcagga cagaatgagg
361 gatagctcgg cccccagctc ggcctcctcg tcagtgacag atctgtactg cacccctcac
421 agcagtaggt cagacctcgt cctgcccggc acggccgggg acttcagcct gagcgccagc
481 ctgtcggcct gtacgctgct ctacgagggg gccgtggagc ccatgcagat cgacgtggac
541 ccccaggaag acccgcagaa tgcacctgac gtcaactacg tggtggagaa ccccagcctg
601 gatctggaac agtacgcggc cagctacagc ggcctgatgc gcatcgaacg gctgcagttc
661 attgctgatc actgccccac gctgcgggtg gaggccctga agatggccct ctccttcgtg
721 cagagaacct ttaacgtgga catgtacgag gagatccacc gcaagctctc agaggccacc
781 agggagctgc agaacgcacc cgacgccatc cctgagagcg gcgtggagcc cccagccctg
841 gacacggcct gggtggaggc cacgcggaag aaggcgctgc tgaagctgga gaagctggac
901 acagacctga agaactacaa gggcaactcc atcaaagaga gcatccggcg cggccacgac
961 gacctgggcg accactacct ggactgtggg gacctcagca acgccctcaa gtgctattcc
1021 cgggcccggg actactgcac cagcgccaaa cacgtcatca acatgtgcct caatgtcatc
1081 aaggtcagcg tctacttgca gaattggtct catgtgctca gctacgtcag caaggctgag
1141 tccaccccag agattgccga gcagcgagga gagcgtgaca gccagaccca ggccatcctc
1201 accaagctca agtgtgccgc aggcttggca gagctggccg ccaggaagta caagcaggct
1261 gccaagtgcc tcctgctggc ttcctttgat cactgtgact tccctgagct gctgtccccc
1321 agcaacgtgg ccatctacgg tggcctgtgc gccttggcta cctttgaccg gcaggagctg
1381 cagcgcaatg tcatctccag cagctccttc aagttgttct tggagctgga gccacaggtc
1441 cgagacatca tcttcaaatt ctacgagtcc aagtacgcct catgtctcaa gatgctggac
1501 gagatgaagg acaacctgct cctggacatg tatctggccc cccatgtcag gaccctgtac
1561 acccagattc gcaaccgtgc cctcatccag tatttcagcc cctacgtgtc agccgacatg
1621 cataggatgg cggcagcctt caataccacg gtggccgccc tggaggacga gctgacgcag
1681 ctaatcctgg aggggctgat cagtgcccgt gtggactcac acagcaagat cctatacgcc
1741 cgggacgtgg atcagcgcag caccaccttt gagaagtctc tgttgatggg caaggagttc
1801 cagcgccgcg ccaaggccat gatgctgcgg gcagctgtgc tccgcaacca gatccatgtc
1861 aagtccccgc ccagagaagg gagccagggg gagctgactc cagccaacag ccagtcccgg
1921 atgagcacca acatgtgagg ggtgaacctt ggcctccagg acatctgcac cccctcccca
1981 cctccacgga cctcggacct ccaggcggct cagtgctgcc tgcggcccag ctaaggggcc
2041 tggccactgg gtgccaccca gcctgtgtgc cctccctggg gctgaggagg caggcggctg
2101 ctagttgtgg cccttcctgg aaggagaggc ctgcagggct cgaccctgtg ggtttctgtc
2161 cccagggagc agactgtgcg gcacccaggc ccagtggcac catttcccag acccctcctg
2221 ttcccgcctc agtcaggtgc agacaagtgg gcggtgtcca ttaaagagca gactcagcgt
2281 taaaaaaaaa aaaaaaa
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