LOCUS BC064393 2282 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens folylpolyglutamate synthase, mRNA (cDNA clone
MGC:70522 IMAGE:5750645), complete cds.
ACCESSION BC064393
VERSION BC064393.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2282)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2282)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 139 Row: m Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 66932983.
FEATURES Location/Qualifiers
source 1..2282
/db_xref="H-InvDB:HIT000261356"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:70522 IMAGE:5750645"
/tissue_type="Lung, Spleen, fetal, pooled"
/clone_lib="NIH_MGC_122"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2282
/gene="FPGS"
/db_xref="GeneID:2356"
/db_xref="HGNC:HGNC:3824"
/db_xref="MIM:136510"
CDS 30..1793
/gene="FPGS"
/codon_start=1
/product="folylpolyglutamate synthase"
/protein_id="AAH64393.1"
/db_xref="GeneID:2356"
/db_xref="HGNC:HGNC:3824"
/db_xref="MIM:136510"
/translation="MSRARSHLRAALFLAAASARGVTTQVAARRGLSAWPVPQEPSME
YQDAVRMLNTLQTNAGYLEQVKRQRGDPQTQLEAMELYLARSGLQVEDLDRLNIIHVT
GTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLY
HRLEETKDGSCVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVV
CGVSSLGIDHTSLLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCP
LYLCPMLEALEEGGPPLTLGLEGEHQRSNAALALQLAHCWLQRQDRHGAGEPKASRPG
LLWQLPLAPVFQPTSHMRLGLRNTEWPGRTQVLRRGPLTWYLDGAHTASSAQACVRWF
RQALQGRERPSGGPEVRVLLFNATGDRDPAALLKLLQPCQFDYAVFCPNLTEVSSTGN
ADQQNFTVTLDQVLLRCLEHQQHWNHLDEEQASPDLWSVPSPEPGGSASLLLAPHPPH
TCSASSLVFSCISHALQWISQGRDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVL
VTGSLHLVGGVLKLLEPALSQ"
BASE COUNT 410 a 726 c 708 g 438 t
ORIGIN
1 cctagagcgc tgccgggggc gccgggacta tgtcgcgggc gcggagccac ctgcgcgccg
61 ctctattcct ggcagcggcg tctgcgcgcg gcgtaacgac ccaggtcgcg gcgcggcggg
121 gcttgagcgc gtggccggtg ccgcaggagc cgagcatgga gtaccaggat gccgtgcgca
181 tgctcaatac cctgcagacc aatgccggct acctggagca ggtgaagcgc cagcggggtg
241 accctcagac acagttggaa gccatggaac tgtacctggc acggagtggg ctgcaggtgg
301 aggacttgga ccggctgaac atcatccacg tcactgggac gaaggggaag ggctccacct
361 gtgccttcac ggaatgtatc ctccgaagct atggcctgaa gacgggattc tttagctctc
421 cccacctggt gcaggttcgg gagcggatcc gcatcaatgg gcagcccatc agtcctgagc
481 tcttcaccaa gtacttctgg cgcctctacc accggctgga ggagaccaag gatggcagct
541 gtgtctccat gcccccctac ttccgcttcc tgacactcat ggccttccac gtcttcctcc
601 aagagaaggt ggacctggca gtggtggagg tgggcattgg cggggcttat gactgcacca
661 acatcatcag gaagcctgtg gtgtgcggag tctcctctct tggcatcgac cacaccagcc
721 tcctggggga tacggtggag aagatcgcat ggcagaaagg gggcatcttt aagcaaggtg
781 tccctgcctt cactgtgctc caacctgaag gtcccctggc agtgctgagg gaccgagccc
841 agcagatctc atgtcctcta tacctgtgtc cgatgctgga ggccctcgag gaaggggggc
901 cgccgctgac cctgggcctg gagggggagc accagcggtc caacgccgcc ttggccttgc
961 agctggccca ctgctggctg cagcggcagg accgccatgg tgctggggag ccaaaggcat
1021 ccaggccagg gctcctgtgg cagctgcccc tggcacctgt gttccagccc acatcccaca
1081 tgcggctcgg gcttcggaac acggagtggc cgggccggac gcaggtgctg cggcgcgggc
1141 ccctcacctg gtacctggac ggtgcgcaca ccgccagcag cgcgcaggcc tgcgtgcgct
1201 ggttccgcca ggcgctgcag ggccgcgaga ggccgagcgg tggccccgag gttcgagtct
1261 tgctcttcaa tgctaccggg gaccgggacc cggcggccct gctgaagctg ctgcagccct
1321 gccagtttga ctatgccgtc ttctgcccta acctgacaga ggtgtcatcc acaggcaacg
1381 cagaccaaca gaacttcaca gtgacactgg accaggtcct gctccgctgc ctggaacacc
1441 agcagcactg gaaccacctg gacgaagagc aggccagccc ggacctctgg agtgtcccca
1501 gcccagagcc cggtgggtcc gcatccctgc ttctggcgcc ccacccaccc cacacctgca
1561 gtgccagctc cctcgtcttc agctgcattt cacatgcctt gcaatggatc agccaaggcc
1621 gagaccccat cttccagcca cctagtcccc caaagggcct cctcacccac cctgtggctc
1681 acagtggggc cagcatactc cgtgaggctg ctgccatcca tgtgctagtc actggcagcc
1741 tgcacctggt gggtggtgtc ctgaagctgc tggagcccgc actgtcccag tagccaaggc
1801 ccggggttgg aggtgggagc ttcccacacc tgcctgcgtt ctccccatga acttacatac
1861 taggtgcctt ttgtttttgg ctttcctggt tctgtctaga ctggcctagg ggccagggct
1921 ttgggatggg aggccgggag aggatgtctt ttttaaggct ctgtgccttg gtctctcctt
1981 cctcctggct gagatagcag aggggctccc cgggtctctc actgttgcag tggcctggcc
2041 gttcagcctg tctcccccaa caccccgcct gcctcctggc tcaggcccag cttattgtgt
2101 gcgctgcctg gccaggccct gggtcttgcc atgtgctggg tggtagattt cctcctccca
2161 gtgccttctg ggaagggaga gggcctctgc ctgggacact gcgggacaga gggtggctgg
2221 agtgaattaa agcctttgtt ttttaaagaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2281 aa
//