LOCUS       BC064360                5086 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens F-box and leucine-rich repeat protein 11, mRNA (cDNA
            clone MGC:74784 IMAGE:5534384), complete cds.
ACCESSION   BC064360
VERSION     BC064360.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5086)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 5086)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-DEC-2003) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: ATCC
            cDNA Library Preparation: Life Technologies, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: National Institutes of Health Intramural
            Sequencing Center (NISC),
            Gaithersburg, Maryland;
            Web site: http://www.nisc.nih.gov/
            Contact: nisc_mgc@nhgri.nih.gov
            Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
            Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
            Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
            Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
            Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
            McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
            Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
            Young,A., Zhang,L.-H. and Green,E.D.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 139 Row: a Column: 9
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 16306579.
FEATURES             Location/Qualifiers
     source          1..5086
                     /db_xref="H-InvDB:HIT000261323"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:74784 IMAGE:5534384"
                     /tissue_type="Uterus, leiomyosarcoma"
                     /clone_lib="NIH_MGC_71"
                     /lab_host="DH10B"
                     /note="Vector: pCMV-SPORT6"
     gene            1..5086
                     /gene="FBXL11"
                     /gene_synonym="CXXC8"
                     /gene_synonym="DKFZP434M1735"
                     /gene_synonym="FBL11"
                     /gene_synonym="FBL7"
                     /gene_synonym="FLJ00115"
                     /gene_synonym="JHDM1A"
                     /gene_synonym="KIAA1004"
                     /gene_synonym="LILINA"
                     /db_xref="GeneID:22992"
                     /db_xref="HGNC:HGNC:13606"
                     /db_xref="MIM:605657"
     CDS             280..3768
                     /gene="FBXL11"
                     /gene_synonym="CXXC8"
                     /gene_synonym="DKFZP434M1735"
                     /gene_synonym="FBL11"
                     /gene_synonym="FBL7"
                     /gene_synonym="FLJ00115"
                     /gene_synonym="JHDM1A"
                     /gene_synonym="KIAA1004"
                     /gene_synonym="LILINA"
                     /codon_start=1
                     /product="F-box and leucine-rich repeat protein 11"
                     /protein_id="AAH64360.1"
                     /db_xref="GeneID:22992"
                     /db_xref="HGNC:HGNC:13606"
                     /db_xref="MIM:605657"
                     /translation="MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKL
                     HTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCV
                     GSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRP
                     STVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGT
                     SVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTF
                     VIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYNIEDRTRVPNKFRYPFYYEMCW
                     YVLERYVYCITNRSHLTKEFQKESLSMDLELNGLESGNGDEEAVDREPRRLSSRRSVL
                     TSPVANGVNLDYDGLGKTCRSLPSLKKTLAGDSSSDCSRGSHNGQVWDPQCAPRKDRQ
                     VHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELANSDPKLAL
                     TGVPIVQWPKRDKLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVRPAAASPIVSGARR
                     RRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCG
                     EVDQNEETQDFEKKLMECCICNEIVHPGCLQMDGEGLLNEELPNCWECPKCYQEDSSE
                     KAQKRKMEESDEEAVQAKVLRPLRSCDEPLTPPPHSPTSMLQLIHDPVSPRGMVTRSS
                     PGAGPSDHHSASRDERFKRRQLLRLQATERTMVREKENNPSGKKELSEVEKAKIRGSY
                     LTVTLQRPTKELHGTSIVPKLQAITASSANLRHSPRVLVQHCPARTPQRGDEEGLGGE
                     EEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRRELCECM
                     RVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWL
                     VNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPADKP
                     GQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAV
                     GSSTRYSLTELNMAGCNKLTDQTLIYLRRIANVTLIDLRGCKQITRKACEHFISDLSI
                     NSLYCLSDEKLIQKIS"
BASE COUNT         1220 a         1376 c         1345 g         1145 t
ORIGIN      
        1 ctcccggtct ccaaagccag aagagaaggt ttgattcagc aactgtttgc tcccttttcc
       61 tggtcgctct gaccctctct ggatactggg ttgatccacg gaaaaaccga agacgacgtt
      121 tgggatttaa ttattcctct cagctttgga atcttttact tctcacttgg acaagaactc
      181 aagagcagaa tctccgtgtt gcaatctggt tcctaaggag gaagaggaag gcagccctgg
      241 agtggtttct ttacagtaat ttcaacagaa gagtgagaga tggaacccga agaagaaagg
      301 attcgttaca gccagagatt gcgtggtacc atgcgacgac gctatgaaga tgatggcatt
      361 tcagatgatg aaattgaagg aaaaagaact tttgacttgg aagagaaact gcacaccaac
      421 aaatataatg ccaattttgt tacttttatg gaaggaaaag attttaatgt agagtatatt
      481 cagcggggtg gcttgagaga tcctctgatt ttcaagaatt ctgatggact cggaataaaa
      541 atgccggatc cagacttcac tgtgaatgat gtcaaaatgt gtgtggggag tcgtcgcatg
      601 gtggatgtca tggacgtgaa cacacagaaa ggcattgaaa tgaccatggc tcagtggaca
      661 cgctactatg agaccccaga ggaggagcga gagaaactct ataatgtcat cagcctcgag
      721 tttagccaca ccaggctgga gaatatggtg cagaggccct ccacggtgga tttcattgac
      781 tgggtagaca acatgtggcc aaggcacttg aaggaaagcc agactgaatc aacaaatgcc
      841 atcttggaga tgcagtaccc taaagtgcag aagtactgtc taatgagtgt tcgaggctgc
      901 tatactgact tccatgtgga ctttggtggt acctctgttt ggtatcacat ccatcaaggg
      961 ggaaaggtct tctggctcat cccccctaca gcccacaacc tggagctgta cgagaattgg
     1021 ctgctgtcag ggaaacaggg agacatcttt ctgggtgacc gggtatcaga ttgtcagcgc
     1081 attgagctca agcagggcta taccttcgtc attccctcag gctggattca tgctgtgtat
     1141 actcctacag acacattagt gtttgggggc aattttttgc atagcttcaa catccctatg
     1201 cagttaaaaa tatacaacat tgaagatcgg acacgggttc caaataagtt tcgctatcca
     1261 ttctactatg agatgtgttg gtatgtgttg gagcgctatg tgtactgcat aaccaaccgt
     1321 tcccacctaa ccaaggaatt tcagaaagag tccctcagca tggatttgga gttaaatggg
     1381 ttggagtctg ggaatgggga tgaggaagca gtggatcgag aaccccgacg cttgagcagc
     1441 aggcgttctg tcctcactag ccctgtagcg aatggagtca acctggatta tgatggactg
     1501 ggcaaaacct gccgaagtct tccaagtctg aagaaaactt tggctgggga ctcatcttct
     1561 gactgtagcc ggggctccca caatggacaa gtgtgggatc cccagtgtgc tccccgaaag
     1621 gacaggcaag tgcatctgac ccattttgag cttgaaggcc ttcgctgcct tgtagataag
     1681 ttggagtctc tgccactgca caagaaatgt gtccccacag ggatagaaga tgaagatgct
     1741 ctcattgctg atgtaaagat tttgctggag gagcttgcca acagcgatcc caagttagcc
     1801 ctcactggag ttcctatagt acagtggcca aaaagggata agcttaaatt ccccactcgg
     1861 ccaaaggtgc gggttcctac catccccatt acgaagcctc acactatgaa accagctcca
     1921 cggttaacac ctgtgaggcc agctgctgcc tccccgattg tgtcaggagc cagacggaga
     1981 cgagtgcgat gtcgaaaatg caaagcctgt gtgcaaggag agtgtggtgt ttgccactac
     2041 tgcagagaca tgaagaagtt tggggggcct ggacgcatga agcagtcctg tgtcctccga
     2101 cagtgcttgg cacccagact gcctcactca gtcacatgtt ccctctgtgg agaggtggat
     2161 cagaatgaag agacacaaga ctttgagaag aaactcatgg aatgctgtat ctgcaatgag
     2221 attgttcatc ctggctgcct ccagatggac ggagaggggt tgcttaacga agaattgcca
     2281 aattgctggg aatgtccaaa gtgctaccag gaggacagct cggagaaagc ccagaagcgg
     2341 aaaatggaag agagtgacga agaagctgtg caagccaaag tcctgcggcc cctgcggagc
     2401 tgcgatgagc ctctcacgcc cccgcctcat tcacccactt ccatgctgca gctcatccat
     2461 gacccggttt ccccccgggg tatggtgact cggtcatccc ctggggctgg ccccagcgac
     2521 caccacagtg ccagccgcga tgagcgcttc aaacggcggc agttgctgcg gctgcaggcc
     2581 acagagcgca ccatggtacg ggaaaaggag aacaatccca gcggcaaaaa ggagctgtct
     2641 gaagttgaga aagccaagat ccggggatcg tacctcactg tcacgctaca gaggcccacc
     2701 aaagagctcc acgggacatc cattgtgccc aagctgcagg ccatcacggc ctcctctgcc
     2761 aaccttcgcc attccccccg tgtgctagtg cagcactgcc cagcccgaac cccccagcgt
     2821 ggggatgagg aggggctggg gggagaggag gaggaagagg aggaggagga ggaggaagat
     2881 gacagtgcag aggagggggg tgcagccagg ctgaatggcc ggggcagttg ggctcaggat
     2941 ggagacgaaa gctggatgca gcgggaggtc tggatgtctg tcttccgcta cctcagccgc
     3001 agagaacttt gtgaatgtat gcgagtgtgc aagacgtggt ataaatggtg ctgcgacaag
     3061 agactttgga caaaaattga cttgagtagg tgtaaggcca ttgtgcccca ggccctcagt
     3121 ggcatcatca agaggcagcc agtcagcctt gacctcagtt ggaccaacat ctctaaaaag
     3181 caactgacat ggctcgtcaa taggctgcca ggactgaaag acctcctcct agcaggctgc
     3241 tcctggtctg cagtctctgc cctcagcacc tccagctgcc cccttctcag gacccttgat
     3301 cttcggtggg cagtaggaat caaggaccct caaattcggg acttgcttac tccaccggct
     3361 gataaaccag gtcaggacaa tcgcagcaag ctccggaaca tgaccgactt ccggctggca
     3421 ggccttgaca tcacagatgc cacgcttcgc ctcataattc gccacatgcc cctcctgtct
     3481 cgactcgacc tcagtcactg cagccacctt acagatcagt cctccaatct actcactgct
     3541 gtcgggtctt ccactcgcta ctctctcaca gagctcaata tggcaggttg caataaattg
     3601 acagaccaga ccctgatcta cctacggcgc attgccaacg tcaccttgat cgaccttcga
     3661 ggatgcaagc agatcactcg aaaagcctgc gagcacttca tctcagactt gtccatcaac
     3721 agcctctact gcctgtctga cgagaagctg atacagaaga tcagctaaga cacacccagc
     3781 ccagattcaa caggaaaccg atcttcccct gactccccac cgaggagagc ctctcctcga
     3841 ccctgcacgg gctctgaggc cagcgtcaca ctccctctct gctctcctgt cccttgagcc
     3901 cttcctctac aggtggggca gagagggtgg tggacaccag gcttatctgc ctgctcctct
     3961 ccctcctaag gaaaagggag tagcagattg atctgagggg aaagcacagg ctgtgctgtc
     4021 gaggcgcctg ctcgcttact cgcctgccag gaggccgggc tctcagtttg gggtgtttgt
     4081 gcaaccttca tctgcactgg gccctgtgcc cctcctcccc atccatggtc cccagcagtg
     4141 cctggttctg agcaaactcc cagggaagaa aacggccctg tctccatggc caggttcttg
     4201 tggtgtccag tgcgcgtctc tcctccatca cactctcccg gcttgcgcag gaggggccag
     4261 cagccccagg agtcccagac ccgtgccgat cacactggtg ctgttgagat ctcccaaacc
     4321 tcacgtcctt aactgtgctc tccctccttt cctctccctt gagcttggtt ctgcccagca
     4381 ctcgtgcttg ttcacataat taggtttccc accccagcct acccgactta cttgctagtc
     4441 tctatgaggt ccttattgca cttattgggg ttgaagctct tcagaggagc tggaactgtc
     4501 taccccaggg acacacccat ttcgttgcta cccaagtgga ttctgagaca ggcaccatct
     4561 ccttgttccc cctctctctt ttgcctccca ctgactgccc ttttccatgt gtcttcattc
     4621 tgcctgaaga aggctttccc aggatgcacg tcctcagagg gagcagccta tctcccccaa
     4681 gctggaggcg gcagaggact gggccaagcc ccaacctgcc tcccagccag gctcctccag
     4741 gcctctggtt tagcggagcc ccctgagccc aggcctgtgt ctagccccag tggctcactg
     4801 aactttcagg gcagtcaggg ggtcctgctt agaagccagt caccagccct ctgcctgcag
     4861 ccatggaagg gggtgtgcac gtgcctctgt gtgtgtggct gagtgtattc tgcgcgtgtg
     4921 tgtggaggga gggagggagg ggagcatggt gtctcccgct ccaccgccct ttgttgagcc
     4981 ccatcagctg ccccctttta ctttgcattg aacggcctgt ccaaagatcc tctctctagg
     5041 gcagcagaga gctttttgca ctttaaaaaa aaaaaaaaaa aaaaaa
//