LOCUS BC063867 4070 bp mRNA linear HUM 04-JAN-2007
DEFINITION Homo sapiens HEAT repeat containing 5A, mRNA (cDNA clone
IMAGE:6186647), partial cds.
ACCESSION BC063867
VERSION BC063867.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4070)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4070)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. James R. Lupski
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 141 Row: e Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..4070
/db_xref="H-InvDB:HIT000261243"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6186647"
/tissue_type="Peripheral Nervous System, dorsal root
ganglion"
/clone_lib="Lupski_dorsal_root_ganglion"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..4070
/gene="HEATR5A"
/db_xref="GeneID:25938"
/db_xref="HGNC:HGNC:20276"
CDS <1..3350
/gene="HEATR5A"
/codon_start=3
/product="HEATR5A protein"
/protein_id="AAH63867.1"
/db_xref="GeneID:25938"
/db_xref="HGNC:HGNC:20276"
/translation="SSQHLNSCIGILYTLAQDSTSPDVQTWALHSLSLIIDSAGPLYY
VHVEPTLSLIIMLLLNVPPTHAEVHQSLGRCLNALITTLGPELQGNSTSISTLRTSCL
LGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLLRRAVL
ACLRQLVQREAAEVSEHAVMLAKDSREELTPDANIREVGLEGALLILLDKETDERLCH
DIKETLNYMLTSMAVEKLSLWLKLCKDVLAASADFTAVTCVDTMQEEEGDKGDDASVL
TTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALAQEMKKRDSRTDF
LVLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPGHVILEQYQAN
VGAALRPAFTSETPPDVTAKACQVCSAWIASGVVSDLNDLRRVHQLLVSSLTKIQAGK
EALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKNHRQPLKTTTCLEDGIRNGSCSS
DGLLDLVYADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENAKLHY
YNSWALILHATALWLTSTGFVVADPDEGASNLSRPVTPTSMCQGSSSGATIKSPEDVY
TDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGIELL
NVLHRVILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPEFGE
GKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGSPGVKATKPQILLEDGSRLV
SAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQALK
GILSSPMARAEKSRTAWTDLLRSALTTILDCWDPVDETHQELDEVSLLTAITVFILST
SPEVTTIPCLQKRCIDKFKATLEIKDPVVQIKTYQLLHSIFQYPNPAVSYPYIYSLAS
CIMEKLQEIDKRKPENTAELEIFQEGIKVLETLVTVAEEHHRAQLVACLLPILISFLL
DENSLGSATSIMRNLHDFALQNLMQIGPQYSSVFKSLVASSPALKARLEAAIKGNQES
VKVKIPTSKYTKSPGKNSSIQLKTSFL"
BASE COUNT 1159 a 876 c 858 g 1177 t
ORIGIN
1 gttcttctca acacctaaat tcttgtattg gaatccttta tactttggcg caggacagca
61 cttctcctga tgtgcagacc tgggcattac attctctatc attgatcatt gattctgctg
121 gcccactcta ttatgtgcat gtggaaccta ccctttctct tattataatg ttgttgttaa
181 atgtgcctcc tactcatgct gaagttcacc aaagccttgg tcgctgtttg aatgccctta
241 ttaccacgtt aggtccagag ctacaaggta acagtacttc aatttctacc ttaaggactt
301 cctgtctact gggttgtgca gtaatgcaag ataacccaga ctgccttgtt caagctcagg
361 ccatctcttg ccttcagcag cttcatatgt ttgctccacg acatgtcaac ttgtctagcc
421 tggttagctg cctctgtgtg aatctttgta gcccctactt gttactgaga agagcagtac
481 tggcttgctt acgtcagctt gtacaaagag aagcagctga agtttcagaa catgctgtta
541 tgcttgctaa ggatagcaga gaagagttga ctccagatgc taacatcaga gaagttggcc
601 ttgagggggc attgttgatc ttactagaca aggagacaga tgagagatta tgccatgata
661 tcaaagagac tttaaattat atgcttacat ctatggcagt ggaaaaactc tccctgtggt
721 taaagctttg taaagatgta cttgctgcat cagctgattt tacagctgta acttgtgtgg
781 atacaatgca agaagaagaa ggagataaag gggatgatgc ctcagtcctg accaccagac
841 gtgatgaaaa atcccatcct tttaccaatc cccgatgggc tactagagtc tttgctgctg
901 aatgtgtctg taggataatt aaccaatgtg agaatgctaa cagtgcacat tttgacattg
961 ctttagcaca agaaatgaaa aaaagagatt caagaactga ctttttggta ctgcatcttg
1021 ctgacttaat tcgcatggct tttatggctg ccacagatca cagtgaccag ctccgtcttt
1081 ctggccttga aatgctgtta gttgttattc ggcgatttgc aactgttcca gaaccagagt
1141 ttccaggtca tgtgattctg gaacagtatc aagccaatgt aggagcagcg cttagaccag
1201 ccttcacttc agagacacca cctgatgtca ctgccaaagc atgtcaggtt tgcagtgcct
1261 ggatagcaag tggagttgta agtgacctta atgatctccg aagagttcat cagttgcttg
1321 tttcatcgtt aactaaaata caggctggaa aagaagctct aagtcactta tataatgaaa
1381 gtgcttctac catggagatc ttagctgtgc ttaaagcctg ggcagaggtc tacataattg
1441 ctgtgcaaag acataaaaac cacagacaac ctttgaagac taccacctgt ttagaagacg
1501 gtatcagaaa tggatcatgt tcatcagatg gactgcttga cttagtctat gcagatcttg
1561 gcacactaag cagactctgg cttgctgcac ttcaggattt tgctctttta actttgcctt
1621 cagaatttgc ctcccaactt cctgctgaag gtggtgcttt ctacacagca gagactagtg
1681 aaaatgcaaa attgcattat tacaactcct gggcacttat cctccatgct acagcattgt
1741 ggcttacaag cacgggtttt gttgttgctg acccagatga aggagcatct aatctctcca
1801 ggcctgtaac accaacttcc atgtgtcagg gttcatcatc tggggctacc ataaagtccc
1861 ctgaggatgt ctacactgat agattccatc ttattttagg aatcagcgtg gaatttctat
1921 gttccttacg ttcagatgca accatggaaa gcataactgc ttgtttacat gcattgcaag
1981 cacttctaga tgtaccttgg cccagatcaa aaattggcag tgatcaggac ttgggtatag
2041 aattgctgaa tgttctacat cgagtaattt taaccagaga atcaccttcc attcagttgg
2101 cttcacttga agtggtaagg cagattatct gtgctgctca agaacatgtg aaggaaaaaa
2161 gacgaagtgc agaagttgat gatggggctg ctgaaaagga aactctgcca gagtttggag
2221 agggaaagga caccggagga cttgtgcctg gaaagtcttt ggtctttgca acactggaat
2281 tgtgtgtatg cattctagtt agacagctcc cagaattaaa ccctaaattg acaggtagcc
2341 caggagtaaa agctacgaag ccacagatac tattagaaga tggaagtaga ttggtttcag
2401 ctgcattggt tatcctttcc gaacttcctg cagtgtgctc tcctgaagga agcatctcaa
2461 ttctccctac tatattgtac ctcacaatcg gggtcctcag agagactgct gtgaagttac
2521 ctgggggcca gttatcttcg acagttgcag cttccctaca ggctctaaaa ggaatattat
2581 cttctcccat ggcccgggca gaaaagagcc gtactgcttg gactgacctt ctccgaagtg
2641 ccttaacaac aattcttgac tgttgggatc cagttgatga aacacaccaa gaacttgatg
2701 aagtcagtct acttactgct atcacagtgt ttattttgtc taccagtcca gaagtaacta
2761 ccatcccatg ccttcagaag cgctgtattg ataaatttaa agctactctt gagataaaag
2821 atcctgtggt acaaatcaag acctaccagc tcctacattc catctttcag tatccaaatc
2881 cagctgtttc ctacccatac atttactctt tagcatcctg tatcatggaa aaactgcagg
2941 aaatagacaa gagaaaacct gaaaacactg ctgagcttga gatcttccaa gaaggcataa
3001 aggtcttaga aacactggtt actgttgctg aagaacacca tcgcgctcag ctggtggcct
3061 gtcttttgcc catcctcatt tccttccttt tggatgaaaa ttctctggga tcagcaactt
3121 ccataatgag aaatttacat gactttgctc tacaaaatct catgcaaatt ggacctcagt
3181 attcatctgt ttttaaaagt ttagtggctt cttctccagc cctaaaagcc cgccttgagg
3241 ctgctataaa gggcaatcag gaaagtgtca aagtcaagat accaacatct aaatatacta
3301 agagtcctgg aaaaaactca agcatccaat taaagaccag tttcctctga tttttttttt
3361 ggaatagtaa gcaccttaat ataataaata cttgatcatt gcctttggtg acaaaaggga
3421 cattgtagac acaagtgccc ttagaggtct agttgattgt tttaccttaa atagctgtga
3481 ctcttcaaag taacagcata cttaacattt ttgtgtgtgt gcgtggggtt tgtgttttgt
3541 tttgttttgt tttttctatt taaaaagaca atggagctaa cttgccagga attttaagaa
3601 agtgctaaag aactaaactt actaaacaat ccactgcttt aaaaatgaaa tgaatttctt
3661 ctaacagtcc atacatatgt ggtatactta atactgtgac agatataaat atgactctag
3721 tgtaaattat ctgcactaat attgtatccc aattgctgat ttaaaattct gctttggccc
3781 ggcacagtgg ctcatccctg taattccagc actttggaag gccaaggcgg gcggatcacg
3841 aggtcgggag tttgagacca gcctgaccaa catggtgaaa ccccgtctct actaaaaata
3901 caaaaattag ccgggtgtgg tggcacacac ctgtaatccc agctactcag gaggccgagg
3961 caggaaaatc gcttgaacct ggcaggcaga ggttgcagtg agccaagatt gtgccactgc
4021 actccagcct gggcgacaga gtgagactcc atctaaaaaa aaaaaaaaaa
//