LOCUS BC063851 4015 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens complement component 7, mRNA (cDNA clone MGC:75123
IMAGE:6184213), complete cds.
ACCESSION BC063851
VERSION BC063851.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4015)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4015)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. James R. Lupski
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 141 Row: d Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 45580687.
FEATURES Location/Qualifiers
source 1..4015
/db_xref="H-InvDB:HIT000261227"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75123 IMAGE:6184213"
/tissue_type="Peripheral Nervous System, dorsal root
ganglion"
/clone_lib="Lupski_dorsal_root_ganglion"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4015
/gene="C7"
/db_xref="GeneID:730"
/db_xref="HGNC:HGNC:1346"
/db_xref="MIM:217070"
CDS 96..2627
/gene="C7"
/codon_start=1
/product="complement component 7"
/protein_id="AAH63851.1"
/db_xref="GeneID:730"
/db_xref="HGNC:HGNC:1346"
/db_xref="MIM:217070"
/translation="MKVISLFILVGFIGEFQSFSSASSPVNCQWDFYAPWSECNGCTK
TQTRRRSVAVYGQYGGQPCVGNAFETQSCEPTRGCPTEEGCGERFRCFSGQCISKSLV
CNGDSDCDEDSADEDRCEDSERRPSCDIDKPPPNIELTGNGYNELTGQFRNRVINTKS
FGGQCRKVFSGDGKDFYRLSGNVLSYTFQVKINNDFNYEFYNSTWSYVKHTSTEHTSS
SRKRSFFRSSSSSSRSYTSHTNEIHKGKSYQLLVVENTVEVAQFINNNPEFLQLAEPF
WKELSHLPSLYDYSAYRRLIDQYGTHYLQSGSLGGEYRVLFYVDSEKLKQNDFNSVEE
KKCKSSGWHFVVKFSSHGCKELENALKAASGTQNNVLRGEPFIRGGGAGFISGLSYLE
LDNPAGNKRRYSAWAESVTNLPQVIKQKLTPLYELVKEVPCASVKKLYLKWALEEYLD
EFDPCHCRPCQNGGLATVEGTHCLCHCKPYTFGAACEQGVLVGNQAGGVDGGWSCWSS
WSPCVQGKKTRSRECNNPPPSGGGRSCVGETTESTQCEDEELEHLRLLEPHCFPLSLV
PTEFCPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEM
HCQKIACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPE
MKNARCVQKENPLTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDERSKRILPL
TVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWGKCDAESSKCVCREASECE
EEGFSICVEVNGKEQTMSECEAGALRCRGQSISVTSIRPCAAETQ"
BASE COUNT 1117 a 834 c 951 g 1113 t
ORIGIN
1 ggcagcctgc tgggctcttc ctgctgttga aaacttaccc ggcccttaca gaggaaatct
61 tcctcctctc ttctgccctg aatgttttcc caaacatgaa ggtgataagc ttattcattt
121 tggtgggatt tataggagag ttccaaagtt tttcaagtgc ctcctctcca gtcaactgcc
181 agtgggactt ctatgcccct tggtcagaat gcaatggctg taccaagact cagactcgca
241 ggcggtcagt tgctgtgtat gggcagtatg gaggccagcc ttgtgttgga aatgcttttg
301 aaacacagtc ctgtgaacct acaagaggat gtccaacaga ggagggatgt ggagagcgtt
361 tcaggtgctt ttcaggtcag tgcatcagca aatcattggt ttgcaatggg gattctgact
421 gtgatgaaga cagtgctgat gaagacagat gtgaggactc agaaaggaga ccttcctgtg
481 atatcgataa acctcctcct aacatagaac ttactggaaa tggttacaat gaactcactg
541 gccagtttag gaacagagtc atcaatacca aaagttttgg tggtcaatgt agaaaggtgt
601 ttagtgggga tggaaaagat ttctacaggc tgagtggaaa tgtcctgtcc tatacattcc
661 aggtgaaaat aaataatgat tttaattatg aattttacaa tagtacttgg tcttatgtaa
721 aacatacgtc gacagaacac acatcatcta gtcggaagcg ctcctttttt agatcttcat
781 catcttcttc acgcagttat acttcacata ccaatgaaat ccataaagga aagagttacc
841 aactgctggt tgttgagaac actgttgaag tggctcagtt cattaataac aatccagaat
901 ttttacaact tgctgagcca ttctggaagg agctttccca cctcccctct ctgtatgact
961 acagtgccta ccgaagatta atcgaccagt acgggacaca ttatctgcaa tctgggtcgt
1021 taggaggaga atacagagtt ctattttatg tggactcaga aaaattaaaa caaaatgatt
1081 ttaattcagt cgaagaaaag aaatgtaaat cctcaggttg gcattttgtc gttaaatttt
1141 caagtcatgg atgcaaggaa ctggaaaacg ctttaaaagc tgcttcagga acccagaaca
1201 atgtattgcg aggagaaccg ttcatcagag ggggaggtgc aggcttcata tctggcctta
1261 gttacctaga gctggacaat cctgctggaa acaaaaggcg atattctgcc tgggcagaat
1321 ctgtgactaa tcttcctcaa gtcataaaac aaaagctgac acctttatat gagctggtaa
1381 aggaagtacc ttgtgcctct gtgaaaaaac tatacctgaa atgggctctt gaagagtatc
1441 tggatgaatt tgacccctgt cattgccggc cttgtcaaaa tggtggtttg gctactgttg
1501 aggggaccca ttgtctgtgc cattgcaaac cgtacacatt tggtgcggcg tgtgagcaag
1561 gagtcctcgt agggaatcaa gcaggagggg ttgatggagg ttggagttgc tggtcctctt
1621 ggagcccctg tgtccaaggg aagaaaacaa gaagccgtga atgcaataac ccacctccca
1681 gtgggggtgg gagatcctgc gttggagaaa cgacagaaag cacacaatgc gaagatgagg
1741 agctggagca cttgaggttg cttgaaccac attgctttcc tttgtctttg gttccaacag
1801 aattctgtcc atcacctcct gccttgaaag atggatttgt tcaagatgaa ggtacaatgt
1861 ttcctgtggg gaaaaatgta gtgtacactt gcaatgaagg atactctctt attggaaacc
1921 cagtggccag atgtggagaa gatttacggt ggcttgttgg ggaaatgcat tgtcagaaaa
1981 ttgcctgtgt tctacctgta ctgatggatg gcatacagag tcacccccaa aaacctttct
2041 acacagttgg tgagaaggtg actgtttcct gttcaggtgg catgtcctta gaaggtcctt
2101 cagcatttct ctgtggctcc agccttaagt ggagtcctga gatgaagaat gcccgctgtg
2161 tacaaaaaga aaatccgtta acacaggcag tgcctaaatg tcagcgctgg gagaaactgc
2221 agaattcaag atgtgtttgt aaaatgccct acgaatgtgg accttccttg gatgtatgtg
2281 ctcaagatga gagaagcaaa aggatactgc ctctgacagt ttgcaagatg catgttctcc
2341 actgtcaggg tagaaattac acccttactg gtagggacag ctgtactctg cctgcctcag
2401 ctgagaaagc ttgtggtgcc tgcccactgt ggggaaaatg tgatgctgag agcagcaaat
2461 gtgtctgccg agaagcatcg gagtgcgagg aagaagggtt tagcatttgt gtggaagtga
2521 acggcaagga gcagacgatg tctgagtgtg aggcgggcgc tctgagatgc agagggcaga
2581 gcatctctgt caccagcata aggccttgtg ctgcggaaac ccagtaggct cctggaggcc
2641 ctggtcagct tgcttggaat ccagcaggca gctggggctg agtgaaaaca tctgcacaac
2701 tgggcactgg acagcttttc cttcttctcc agtgtctacc ttcctcctca actcccagcc
2761 atctgtataa acacaatcct ttgttctccc aaatctgaat cgaattactc ttttgcctcc
2821 tttttaatgt cagtaaggat atgagccttt gcacaggctg gctgcgtgtt cttgaaatag
2881 gtgttacctt ctctgggcct tggtttttta aaatctgtaa aattagagga ttgcactaga
2941 gaaacttgaa tgctccattc aggcctatca ttttattaag tatgattgac acagcccatg
3001 ggccagaaca cactctacaa aatgactagg ataacagaaa gaacgtgatc tcctgattag
3061 agagggtggt tttcctcaat ggaaccaaat ataaagagga cttgaacaaa aatgacagat
3121 acaaactatt tctatcctga gtagtaatct cacacttcat cctatagagt caaccaccac
3181 agataggaat tccttattct ttttttaatt tttttaagac agagtctcac tttgttgccc
3241 aggctggagc gcagtggggt gatctcatct ccctgcaacc tccgcctcct gggttcaagc
3301 gattcttgtg cctcagcttc ccaagcagct gggattacag gtgcccgcca ccacgcccag
3361 ctaatttttg catttttagt agagatgggg tttcaccatg ttggccacgc tcgtctccaa
3421 ctcctgacct caggtaatcc gcctgccttg gcctcccaaa gtgctgggat tacagacatg
3481 aaccaccacg cctggctgga atacttactc ttgtcgggag attgaaccac taaaatgtta
3541 gagcagaatt cattatgctg tggtcacagg ggtgtcttgt ctgagaacaa atacaattca
3601 gtcttctctt tggggtttta gtatgtgtca aacataggac tggaagtttg cccctgttct
3661 tttttctttt gaaagaacat cagttcatgc ctgaggcatg agtgactgtg catttgagaa
3721 tagttttccc tattctgtgg atacagtccc agagttttca gggagtacac aggtagatta
3781 gtttgaagca ttgacctttt atttattcct tatttctctt tcatcaaaac aaaacagcag
3841 ctgtgggagg agaaatgaga gggcttaaat gaaatttaaa ataagctata ttatacaaat
3901 actatctctg tattgttctg accctggtaa atatatttca aaacttcaga tgacaaggat
3961 tagaacactc attaaagatg ctattcttca gaaaaaaaaa aaaaaaaaaa aaaaa
//