LOCUS BC063840 3399 bp mRNA linear HUM 23-DEC-2003
DEFINITION Homo sapiens bromodomain containing 2, mRNA (cDNA clone MGC:74927
IMAGE:6181728), complete cds.
ACCESSION BC063840
VERSION BC063840.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3399)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3399)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. James R. Lupski
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 141 Row: c Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 12408641.
FEATURES Location/Qualifiers
source 1..3399
/db_xref="H-InvDB:HIT000261216_04"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:74927 IMAGE:6181728"
/tissue_type="Peripheral Nervous System, dorsal root
ganglion"
/clone_lib="Lupski_dorsal_root_ganglion"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3399
/gene="BRD2"
/gene_synonym="D6S113E"
/gene_synonym="FSRG1"
/gene_synonym="KIAA9001"
/gene_synonym="NAT"
/gene_synonym="RING3"
/gene_synonym="RNF3"
/db_xref="GeneID:6046"
/db_xref="MIM:601540"
CDS 170..2680
/gene="BRD2"
/gene_synonym="D6S113E"
/gene_synonym="FSRG1"
/gene_synonym="KIAA9001"
/gene_synonym="NAT"
/gene_synonym="RING3"
/gene_synonym="RNF3"
/codon_start=1
/product="BRD2 protein"
/protein_id="AAH63840.1"
/db_xref="GeneID:6046"
/db_xref="MIM:601540"
/translation="MLQNVTPHNKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFE
SPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQP
VDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTD
DIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAV
SSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKK
KGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDS
QQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKH
PMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRY
AKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESE
SSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGR
AGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLQAGVQWRDL
GLLQPPLLGFKRFSCLSLPSSQDYRLPKKATKTAPPALPTGYDSEEEEESRPMSYDEK
RQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLS
CLRKKPRKPYTIKKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTES
SSAQQVAVSRLSASSSSSDSSSSSSSSSSSDTSDSDSG"
misc_feature 398..715
/gene="BRD2"
/gene_synonym="D6S113E"
/gene_synonym="FSRG1"
/gene_synonym="KIAA9001"
/gene_synonym="NAT"
/gene_synonym="RING3"
/gene_synonym="RNF3"
/note="BROMO; Region: bromo domain"
/db_xref="CDD:smart00297"
misc_feature 1211..1534
/gene="BRD2"
/gene_synonym="D6S113E"
/gene_synonym="FSRG1"
/gene_synonym="KIAA9001"
/gene_synonym="NAT"
/gene_synonym="RING3"
/gene_synonym="RNF3"
/note="BROMO; Region: bromo domain"
/db_xref="CDD:smart00297"
BASE COUNT 982 a 885 c 834 g 698 t
ORIGIN
1 cccaaagaga ctgctttcgt gccggccagg cagggggttt gtcgcctcga ggcccaagag
61 gaacggcctc cccccaactt agcgggttat gctggaccgg gcggtgaggg gaaccgaggc
121 cacccggact ttccgcggct gagggcagcg ccggttcctt gcggtcaaga tgctgcaaaa
181 cgtgactccc cacaataagc tccctgggga agggaatgca gggttgctgg ggctgggccc
241 agaagcagca gcaccaggga aaaggattcg aaaaccctct ctcttgtatg agggctttga
301 gagccccaca atggcttcgg tgcctgcttt gcaacttacc cctgccaacc caccaccccc
361 ggaggtgtcc aatcccaaaa agccaggacg agttaccaac cagctgcaat acctacacaa
421 ggtagtgatg aaggctctgt ggaaacatca gttcgcatgg ccattccggc agcctgtgga
481 tgctgtcaaa ctgggtctac cggattatca caaaattata aaacagccta tggacatggg
541 tactattaag aggagacttg aaaacaatta ttattgggct gcttcagagt gtatgcaaga
601 ttttaatacc atgttcacca actgttacat ttacaacaag cccactgatg atattgtcct
661 aatggcacaa acgctggaaa agatattcct acagaaggtt gcatcaatgc cacaagaaga
721 acaagagctg gtagtgacca tccctaagaa cagccacaag aagggggcca agttggcagc
781 gctccagggc agtgttacca gtgcccatca ggtgcctgcc gtctcttctg tgtcacacac
841 agccctgtat actcctccac ctgagatacc taccactgtc ctcaacattc cccacccatc
901 agtcatttcc tctccacttc tcaagtcctt gcactctgct ggacccccgc tccttgctgt
961 tactgcagct cctccagccc agccccttgc caagaaaaaa ggcgtaaagc ggaaagcaga
1021 tactaccacc cctacaccta cagccatctt ggctcctggt tctccagcta gccctcctgg
1081 gagtcttgag cctaaggcag cacggcttcc ccctatgcgt agagagagtg gtcgccccat
1141 caagccccca cgcaaagact tgcctgactc tcagcaacaa caccagagct ctaagaaagg
1201 aaagctttca gaacagttaa aacattgcaa tggcattttg aaggagttac tctctaagaa
1261 gcatgctgcc tatgcttggc ctttctataa accagtggat gcttctgcac ttggcctgca
1321 tgactaccat gacatcatta agcaccccat ggacctcagc actgtcaagc ggaagatgga
1381 gaaccgtgat taccgggatg cacaggagtt tgctgctgat gtacggctta tgttctccaa
1441 ctgctataag tacaatcccc cagatcacga tgttgtggca atggcacgaa agctacagga
1501 tgtatttgag ttccgttatg ccaagatgcc agatgaacca ctagaaccag ggcctttacc
1561 agtctctact gccatgcccc ctggcttggc caaatcgtct tcagagtcct ccagtgagga
1621 aagtagcagt gagagctcct ctgaggaaga ggaggaggaa gatgaggagg acgaggagga
1681 agaagagagt gaaagctcag actcagagga agaaagggct catcgcttag cagaactaca
1741 ggaacagctt cgggcagtac atgaacaact ggctgctctg tcccagggtc caatatccaa
1801 gcccaagagg aaaagagaga aaaaagagaa aaagaagaaa cggaaggcag agaagcatcg
1861 aggccgagct ggggccgatg aagatgacaa ggggcctagg gcaccccgcc cacctcaacc
1921 taagaagtcc aagaaagcaa gtggcagtgg gggtggcagt gctgctttag gcccttctgg
1981 ctttggacct tctggaggaa gtggcaccaa actccaggct ggagtgcagt ggcgtgatct
2041 cggcttactg caacctccac ttctcgggtt caagcgattc tcctgcctca gcctcccaag
2101 tagccaggat tacaggctcc ccaaaaaggc cacaaagaca gccccacctg ccctgcctac
2161 aggttatgat tcagaggagg aggaagagag caggcccatg agttacgatg agaagcggca
2221 gctgagcctg gacatcaaca aattacctgg ggagaagctg ggccgagttg tgcatataat
2281 ccaagccagg gagccctctt tacgtgattc aaacccagaa gagattgaga ttgattttga
2341 aacactcaag ccatccacac ttagagagct tgagcgctat gtcctttcct gcctacgtaa
2401 gaaaccccgg aagccctaca ccattaagaa gcctgtggga aagacaaagg aggaactggc
2461 tttggagaaa aagcgggaat tagaaaagcg gttacaagat gtcagcggac agctcaattc
2521 tactaaaaag ccccccaaga aagcgaatga gaaaacagag tcatcctctg cacagcaagt
2581 agcagtgtca cgccttagcg cttccagctc cagctcagat tccagctcct cctcttcctc
2641 gtcgtcgtct tcagacacca gtgattcaga ctcaggctaa ggggtcaggc cagatggggc
2701 aggaaggctc cgcaggaccg gacccctaga ccaccctgcc ccacctgccc cttccccctt
2761 tgctgtgaca cttcttcatc tcaccccccc ccgcccccct ctaggagagc tggctctgca
2821 gtgggggagg gatgcaggga catttactga aggagggaca tggacaaaac aacattgaat
2881 tcccagcccc attggggagt gatctcttgg acacagagcc cccattcaaa atggggcagg
2941 gcaagggtgg gagtgtgcaa agccctgatc tggagttacc tgaggccata gctgccctat
3001 tcacttctaa gggccctgtt ttgagattgt ttgttctaat ttattttaag ctaggtaagg
3061 ctggggggag ggtggggcca tggtcccctc agcctccatg gggagggaag aagggggagc
3121 tcttttttta cgttgatttt tttttttcta ctctgttttc cctttttcct tccgctccat
3181 ttggggccct gggggtttca gtcatctccc catttggtcc cctggactgt ctttgttgat
3241 tctaacttgt aaataaagaa aatattattc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3301 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3361 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//