LOCUS BC063697 2470 bp mRNA linear HUM 07-AUG-2008
DEFINITION Homo sapiens keratin 1, mRNA (cDNA clone MGC:75449 IMAGE:4746001),
complete cds.
ACCESSION BC063697
VERSION BC063697.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2470)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2470)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: James Cleaver, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 134 Row: l Column: 8.
FEATURES Location/Qualifiers
source 1..2470
/db_xref="H-InvDB:HIT000261150"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75449 IMAGE:4746001"
/tissue_type="Skin, normal"
/clone_lib="NCI_CGAP_Skn3"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene 1..2470
/gene="KRT1"
/gene_synonym="CK1"
/gene_synonym="K1"
/gene_synonym="KRT1A"
/db_xref="GeneID:3848"
/db_xref="HGNC:HGNC:6412"
/db_xref="MIM:139350"
CDS 42..1976
/gene="KRT1"
/gene_synonym="CK1"
/gene_synonym="K1"
/gene_synonym="KRT1A"
/codon_start=1
/product="keratin 1"
/protein_id="AAH63697.1"
/db_xref="GeneID:3848"
/db_xref="HGNC:HGNC:6412"
/db_xref="MIM:139350"
/translation="MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGG
RFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGG
GFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQS
LLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQV
DTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINK
RTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETN
VILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVR
NSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDA
LQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTS
HTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSY
GSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVK
SSGGSSSVRFVSTTYSGVTR"
BASE COUNT 606 a 548 c 735 g 581 t
ORIGIN
1 ttcccttact ctaccttgct cctacttttc tctaagtcaa catgagtcga cagtttagtt
61 ccaggtctgg gtaccgaagt ggagggggct tcagctctgg ctctgctggg atcatcaact
121 accagcgcag gaccaccagc agctccacac gccgcagtgg aggaggtggt gggagatttt
181 caagctgtgg tggtggtggt ggtagctttg gtgctggtgg tggatttgga agtcggagtc
241 ttgttaacct tggtggcagt aaaagcatct ccataagtgt ggctagagga ggtggacgtg
301 gtagtggctt tggtggtggt tatggtggtg gtggctttgg tggtggtggc tttggtggtg
361 gtggctttgg tggaggtggc attgggggtg gtggctttgg tggttttggc agtggtggtg
421 gtggttttgg tggaggtggc tttgggggtg gtggatatgg gggtggttat ggtcctgtct
481 gccctcctgg tggcatacaa gaagtcacta tcaaccagag ccttcttcag cccctcaatg
541 tggagattga ccctgagatc caaaaggtga agtctcgaga aagggagcaa atcaagtcac
601 tcaacaacca atttgcctcc ttcattgaca aggtgaggtt cctggagcag cagaaccagg
661 tactgcaaac aaaatgggag ctgctgcagc aggtagatac ctccactaga acccataatt
721 tagagcccta ctttgagtca ttcatcaaca atctccgaag gagagtggac caactgaaga
781 gtgatcaatc tcggttggat tcggaactga agaacatgca ggacatggtg gaggattacc
841 ggaacaagta tgaggatgaa atcaacaagc ggacaaatgc agagaatgaa tttgtgacca
901 tcaagaagga tgtggatggt gcttatatga ccaaggtgga ccttcaggcc aaacttgaca
961 acttgcagca ggaaattgat ttccttacag cactctacca agcagagttg tctcagatgc
1021 agactcaaat cagtgaaact aatgtcatcc tctctatgga caacaaccgc agtctcgacc
1081 tggacagcat cattgctgag gtcaaggccc agtacgagga tatagcccag aagagcaaag
1141 ctgaggccga gtccttgtac cagagcaagt atgaagagct gcagatcact gctggcagac
1201 atggggatag tgtgagaaat tcaaagatag aaatttctga gctgaatcgt gtgatccaga
1261 gacttagatc tgaaatcgac aatgtcaaga agcagatctc caacttgcag cagtccatca
1321 gtgatgcaga gcagcgtggc gagaatgccc tcaaggatgc caagaacaag ctgaatgacc
1381 tggaggatgc cctgcagcag gccaaggaag acctggcccg cctgctgcgc gactaccagg
1441 agctgatgaa caccaagctg gccctggatc tggagattgc cacctacagg accctcctgg
1501 agggagaaga aagcaggatg tctggagaat gtgccccgaa cgtgagtgtg tctgtgagca
1561 caagccacac caccatcagt ggaggtggca gccgaggagg tggcggcggt ggctacggct
1621 ctggaggtag cagctatggc tccggaggtg gtagctatgg ttctggaggt ggcggcggcg
1681 gcggccgtgg cagctatggc tccggaggta gcagctacgg ctccggaggt ggcagctatg
1741 gctctggagg tggcggcggc ggccatggca gctacggctc cggaagcagc agtgggggct
1801 acagaggtgg ctctggaggc ggcggcggcg gcagctctgg cggccggggc tctggcggcg
1861 ggagctctgg aggctccata ggaggccggg gatccagctc tgggggtgtc aagtcctctg
1921 gtggcagttc cagcgtgagg tttgtttcta ccacttattc cggagtaacc agataaagag
1981 atgccctctg tttcattagc tctagttctc ccccagcatc actaacaaat atgcttggca
2041 agaccgaggt cgatttgtcc cagccttacc ggagaaaaga gctatggtta gttacactag
2101 ctcatcctat tcccccagct ctttcttttc tgctgtttcc caatgaagtt ttcagatcag
2161 tggcaatctc agtcccctgg ctatgaccct gctttgttct ttccctgaga aacagttcag
2221 cagtgaccac cacccacatg acatttcaaa gcacctcctt aagccagcca gagtaggacc
2281 agttagaccc agggtgtgga cagctcctta gcatcttatc tctgtgctgt tttggttttg
2341 tacataaggt gtaagcaagt tgtttttctt ttgtggagag gtcttaaact ccccatttcc
2401 ttgttttgct gcaataaact gcatttgaaa ttcaaaaaaa aaaaaaaaaa aaaaaaaaaa
2461 aaaaaaaaaa
//