LOCUS BC063647 2686 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens arachidonate 15-lipoxygenase, type B, mRNA (cDNA clone
MGC:75485 IMAGE:4804186), complete cds.
ACCESSION BC063647
VERSION BC063647.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2686)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2686)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: James Cleaver, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 134 Row: n Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4557308.
FEATURES Location/Qualifiers
source 1..2686
/db_xref="H-InvDB:HIT000261101"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75485 IMAGE:4804186"
/tissue_type="Skin, normal"
/clone_lib="NCI_CGAP_Skn3"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene 1..2686
/gene="ALOX15B"
/db_xref="GeneID:247"
/db_xref="HGNC:HGNC:434"
/db_xref="MIM:603697"
CDS 73..2103
/gene="ALOX15B"
/codon_start=1
/product="arachidonate 15-lipoxygenase, type B"
/protein_id="AAH63647.1"
/db_xref="GeneID:247"
/db_xref="HGNC:HGNC:434"
/db_xref="MIM:603697"
/translation="MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKE
FTAGAEEDFQVTLPEDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHL
LFPCYQWLEGAGTLVLQEGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPH
CLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFN
FRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGT
SLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLS
QTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQL
PHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLN
YSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDREL
QAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAW
MPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYP
DEHFTEEAPRRSIATFQSRLAQISRGIQERNRGLVLPYTYLDPPLIENSVSI"
BASE COUNT 622 a 831 c 724 g 509 t
ORIGIN
1 caggcgtgtc ccagggggga gccccgctct gcagccctgt gcgccgtaga gagctggact
61 taggctggca gcatggccga gttcagggtc agggtgtcca ccggagaagc cttcggggct
121 ggcacatggg acaaagtgtc tgtcagcatc gtggggaccc ggggagagag ccccccactg
181 cccctggaca atctcggcaa ggagttcact gcgggcgctg aggaggactt ccaggtgacg
241 ctcccggagg acgtaggccg agtgctgctg ctgcgcgtgc acaaggcgcc cccagtgctg
301 cccctgctgg ggcccctggc cccggatgcc tggttctgcc gctggttcca gctgacaccg
361 ccgcggggcg gccacctcct cttcccctgc taccagtggc tggagggggc ggggaccctg
421 gtgctgcagg agggtacagc caaggtgtcc tgggcagacc accaccctgt gctccagcaa
481 cagcgccagg aggagcttca ggcccggcag gagatgtacc agtggaaggc ttacaaccca
541 ggttggcctc actgcctgga tgaaaagaca gtggaagact tggagctcaa tatcaaatac
601 tccacagcca agaatgccaa cttttatcta caggctggct ctgcttttgc agagatgaaa
661 atcaaggggt tgctggaccg caaggggctc tggaggagtc tgaatgagat gaaaaggatc
721 ttcaacttcc ggaggacccc agcagctgag cacgcatttg agcactggca ggaggatgcc
781 ttcttcgcct cccagttcct gaatggtctc aaccctgtcc tgatccgccg ctgtcactac
841 ctcccaaaga acttccccgt cactgatgcc atggtggcct cagtgttggg tcctgggacc
901 agcttgcagg ctgagctaga gaagggctcc ctgttcttgg tggatcacgg catcctctct
961 ggcatccaga ccaatgtcat taatgggaag cctcagttct ctgcggcccc aatgaccctg
1021 ctataccaga gcccaggctg cgggccgctg ctgcctctcg ccatccagct cagccagacc
1081 cccggcccaa acagccccat cttcctgccc actgatgaca agtgggactg gttgctggcc
1141 aagacctggg tgcgcaatgc cgagttctcc ttccatgagg ccctcacgca cctgctgcac
1201 tcacatctgc tgcctgaggt cttcaccctg gctaccctgc gtcagctgcc ccactgccac
1261 cctctcttca agctgctgat cccgcacacc cgatacaccc tgcacatcaa cacactcgcc
1321 cgggagctgc ttatcgtgcc agggcaggtg gtggacaggt ccacaggcat cggcattgaa
1381 ggcttctctg agttgataca gaggaacatg aagcagctga actattctct cctgtgtctg
1441 cctgaggata tccggacccg aggagttgaa gacatcccag gctactacta ccgtgatgat
1501 gggatgcaga tctggggtgc agtggaacgc tttgtctctg aaatcatcgg tatctactac
1561 ccaagtgatg agtctgtcca agatgacaga gagctccagg cctgggtcag agagatcttc
1621 tccaagggct tcctaaacca ggagagctca ggtataccct cctcactgga gacccgggaa
1681 gccctggtgc agtatgtcac catggtgata ttcacctgct ccgccaagca tgcggctgtc
1741 agtgcagggc agtttgactc ctgtgcttgg atgcccaacc tgccacccag catgcagctg
1801 ccaccaccca cctccaaagg cctggcaaca tgcgagggct tcatagccac cctcccacct
1861 gtcaatgcca catgtgatgt catccttgct ctctggttgc tgagcaagga gcctggagac
1921 caaaggcccc tgggcaccta tccggatgag cacttcacag aggaggcccc tcggcggagc
1981 atcgccacct tccagagccg cctggcccag atctcgaggg gcatccagga gcggaaccgg
2041 ggcctggtgc tgccctacac ctacctagac cctcccctca tcgagaacag cgtctccatc
2101 taaatcccag gggaacacag gcccagatga catccctttg accacatcgc tctaggataa
2161 ctggcaccca gagaaaagga ctcctcagaa aaaacaggcc cccatgtgcc tctcctggga
2221 caaccagact ctgtaactca cccccaccac catacacaca cacaaaaaca gaaacaaaat
2281 caaaacagag aaagcagaaa atctaccaag aacagagtct caggacagaa ccactgagtc
2341 ttttggaggc tccaagcctc aaagtgcccg cagagcccac cttgagggtt ttgctagttg
2401 gttttgtttt gcgttttaca gccgtggggg gaagcacata atcccgcccc ggggcccact
2461 agcatccact gattggacct tatggtcacc caactcaagg acagccacca agaagtggct
2521 gccaaagaga ctgggcgcag tggctcatgc ccataatccc agcactttgg gagatggagg
2581 cgggaaaatc atttgaggtc agaagttcaa ggccagcctg gacgacatag cgagactcca
2641 cctctaccaa aaaataaaaa ttaaaaaaca aaaaaaaaaa aaaaaa
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