LOCUS BC063595 2360 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens gasdermin C, mRNA (cDNA clone MGC:75457
IMAGE:4752106), complete cds.
ACCESSION BC063595
VERSION BC063595.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2360)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2360)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: James Cleaver, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 134 Row: m Column: 2.
FEATURES Location/Qualifiers
source 1..2360
/db_xref="H-InvDB:HIT000261050"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75457 IMAGE:4752106"
/tissue_type="Skin, squamous cell carcinoma"
/clone_lib="NCI_CGAP_Skn4"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene 1..2360
/gene="GSDMC"
/gene_synonym="MLZE"
/db_xref="GeneID:56169"
/db_xref="HGNC:HGNC:7151"
/db_xref="MIM:608384"
CDS 411..1937
/gene="GSDMC"
/gene_synonym="MLZE"
/codon_start=1
/product="gasdermin C"
/protein_id="AAH63595.1"
/db_xref="GeneID:56169"
/db_xref="HGNC:HGNC:7151"
/db_xref="MIM:608384"
/translation="MPSMLERISKNLVKEIGSKDLTPVKYLLSATKLRQFVILRKKKD
SRSSFWEQSDYVPVEFSLNDILEPSSSVLETVVTGPFHFSDIMIQKHKADMGVNVGIE
VSVSGEASVDHGCSLEFQIVTIPSPNLEDFQKRKLLDPEPSFLKECRRRGDNLYVVTE
AVELINNTVLYDSSSVNILGKIALWITYGKGQGQGESLRVKKKALTLQKGMVMAYKRK
QLVIKEKAILISDDDEQRTFQDEYEISEMVGYCAARSEGLLPSFHTISPTLFNASSND
MKLKPELFLTQQFLSGHLPKYEQVHILPVGRIEEPFWQNFKHLQEEVFQKIKTLAQLS
KDVQDVMFYSILAMLRDRGALQDLMNMLELDSSGHLDGPGGAILKKLQQDSNHAWFNP
KDPILYLLEAIMVLSDFQHDLLACSMEKRILLQQQELVRSILEPNFRYPWSIPFTLKP
ELLAPLQSEGLAITYGLLEECGLRTELDNPRSTWDVEAKMPLSALYGTLSLLQQLAEA
"
BASE COUNT 721 a 508 c 542 g 589 t
ORIGIN
1 gtttgtctga caatttctac ttgaccgcag gaggtctgaa gattggaagg ggccctactc
61 aattgtgcta tttttctctc tttttttttt tttttgagac ggagttgccc aggctggagt
121 gcagcggcat ggtctcagct cactgcaacc tctgcctccc gggttcaagc agttctctgc
181 ctcagcctcc caagtagctg ggattacagg tgcctgccac cattcctggc taatttttgt
241 attttcagta gagacagggt ttcaccatct tggcctggct gatcttgaac tcctgacctc
301 gtgatccacc ggcctcagcc tcccaaagtg ctgggattac agacgtgagc caccgtgccc
361 ggccaatcct gctatttctc tacaggacaa agggatatat aatctgcaac atgccctcca
421 tgttggaacg cattagcaaa aatttggtca aagagattgg aagcaaagac ctgacacctg
481 tcaaatacct attgagtgcc accaaattac gtcagtttgt tatattacga aagaagaagg
541 attctcgttc atcattttgg gaacaatctg actatgttcc agttgaattc tccctcaatg
601 acatcctgga gccaagttct tcagtcctag aaactgttgt gacaggaccg ttccacttca
661 gtgacattat gatccagaag cataaggctg acatgggtgt gaatgttggt atagaagtga
721 gtgtgtcagg ggaggcctct gtggaccatg gatgctccct cgagtttcaa attgttacca
781 tcccatcacc aaacctggaa gactttcaaa aaaggaaact gttggatcca gagccatcat
841 ttctgaagga gtgccggagg agaggggaca acctgtacgt ggtgacagag gctgttgaac
901 tgatcaacaa tactgtgctg tacgatagca gtagtgtgaa tattttaggg aaaattgctc
961 tttggattac ctatggcaag ggtcaaggcc aaggagagag tctcagagtg aagaagaagg
1021 cgctgactct tcagaaaggc atggtgatgg cttataagag gaagcagctg gttatcaagg
1081 agaaagccat tctcatctca gatgatgatg aacagagaac ctttcaagat gagtacgaaa
1141 tttccgaaat ggtaggctac tgtgctgcga ggagtgaggg gttgctacca tcatttcata
1201 ccatctctcc aaccctcttc aatgcctcat ccaatgatat gaagttaaaa ccagagctat
1261 ttctgacaca gcaatttttg agcgggcatt tgccaaaata cgaacaagtt cacatcctcc
1321 cagtaggaag aatagaggaa cccttctggc aaaatttcaa gcatctacaa gaggaggttt
1381 tccagaaaat aaagacactg gctcagctct caaaggatgt tcaggatgtc atgttctaca
1441 gtatcctggc catgctcaga gacagagggg ctctacagga cctgatgaac atgctggaat
1501 tggacagctc aggtcatttg gatggccctg gtggtgccat cctaaagaaa cttcaacagg
1561 attcaaacca tgcatggttt aacccaaagg accccattct ttatctcctt gaagccataa
1621 tggtgctgag tgacttccaa cacgatttgc tggcctgttc catggagaag aggatcctgc
1681 ttcagcaaca ggagctggta aggagcatcc tggagccaaa cttcagatac ccctggagca
1741 ttcccttcac cctcaaacct gagctcctcg ccccactcca gagtgagggt ttggccatca
1801 cctatggcct gctggaggag tgtggcctta ggacggagct ggataacccc aggtcaacct
1861 gggatgtaga agcaaagatg cccctgtctg ccctctatgg gactctctca ttgctgcagc
1921 agctggctga ggcctaagcc ctccctgatg ggcagtcagt ccagagatgc tggccctcgc
1981 ccagtctatg ctgtgagtgt ccttatgggt gcaagagata gggctgtgcc tctctgcgtt
2041 tccaggtgga gtagagacag taatgggtag agactttagg aaatgttttg gggtggtgga
2101 atactctata tattgacaag agtttatata ttgacaagag tttatatatt tgtcaaaact
2161 cctcaaatag tatgttaaag acgtaagcgt ttcactatgt ataaatttta cttcaaaata
2221 ataaaaacaa atactgactc taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2281 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2341 aaaaaaaaaa aaaaaaaaaa
//