LOCUS BC063574 1543 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aldo-keto reductase family 1, member C2 (dihydrodiol
dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid
dehydrogenase, type III), mRNA (cDNA clone MGC:70847
IMAGE:3877666), complete cds.
ACCESSION BC063574
VERSION BC063574.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1543)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1543)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 134 Row: c Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 56121816.
FEATURES Location/Qualifiers
source 1..1543
/db_xref="H-InvDB:HIT000261029"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:70847 IMAGE:3877666"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_68"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1543
/gene="AKR1C2"
/gene_synonym="AKR1C-pseudo"
/gene_synonym="BABP"
/gene_synonym="DD"
/gene_synonym="DD2"
/gene_synonym="HAKRD"
/gene_synonym="HBAB"
/gene_synonym="MCDR2"
/db_xref="GeneID:1646"
/db_xref="HGNC:HGNC:385"
/db_xref="MIM:600450"
CDS 281..1252
/gene="AKR1C2"
/gene_synonym="AKR1C-pseudo"
/gene_synonym="BABP"
/gene_synonym="DD"
/gene_synonym="DD2"
/gene_synonym="HAKRD"
/gene_synonym="HBAB"
/gene_synonym="MCDR2"
/codon_start=1
/product="aldo-keto reductase family 1, member C2
(dihydrodiol dehydrogenase 2; bile acid binding protein;
3-alpha hydroxysteroid dehydrogenase, type III)"
/protein_id="AAH63574.1"
/db_xref="GeneID:1646"
/db_xref="HGNC:HGNC:385"
/db_xref="MIM:600450"
/translation="MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEA
GFHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERS
LKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLA
KSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSA
LGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQR
IRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY"
BASE COUNT 461 a 354 c 353 g 375 t
ORIGIN
1 gaaagtgtgt agcacctcca ccttctctct ctctctccct ctccctctcc tgccagccaa
61 gtgaagacat gcttacttcc ccttcacctt ccttcatgat ggtaagaaac ggttgaactg
121 gatgcaattt ttatcacagc ttgtgtaaga ctgcctctgt ccctcctctc acatgccatt
181 ggttaaccag cagacagtgt gctcaggggc gttgccagct cattgctctt atagcctgtg
241 agggaggaag aaacatttgc taaccaggcc agtgacagaa atggattcga aataccagtg
301 tgtgaagctg aatgatggtc acttcatgcc tgtcctggga tttggcacct atgcgcctgc
361 agaggttcct aaaagtaaag ctctagaggc cgtcaaattg gcaatagaag ccgggttcca
421 ccatattgat tctgcacatg tttacaataa tgaggagcag gttggactgg ccatccgaag
481 caagattgca gatggcagtg tgaagagaga agacatattc tacacttcaa agctttggag
541 caattcccat cgaccagagt tggtccgacc agccttggaa aggtcactga aaaatcttca
601 attggactat gttgacctct atcttattca ttttccagtg tctgtaaagc caggtgagga
661 agtgatccca aaagatgaaa atggaaaaat actatttgac acagtggatc tctgtgccac
721 atgggaggcc atggagaagt gtaaagatgc aggattggcc aagtccatcg gggtgtccaa
781 cttcaaccac aggctgctgg agatgatcct caacaagcca gggctcaagt acaagcctgt
841 ctgcaaccag gtggaatgtc atccttactt caaccagaga aaactgctgg atttctgcaa
901 gtcaaaagac attgttctgg ttgcctatag tgctctggga tcccaccgag aagaaccatg
961 ggtggacccg aactccccgg tgctcttgga ggacccagtc ctttgtgcct tggcaaaaaa
1021 gcacaagcga accccagccc tgattgccct gcgctaccag ctacagcgtg gggttgtggt
1081 cctggccaag agctacaatg agcagcgcat cagacagaac gtgcaggtgt ttgaattcca
1141 gttgacttca gaggagatga aagccataga tggcctaaac agaaatgtgc gatatttgac
1201 ccttgatatt tttgctggcc cccctaatta tccattttct gatgaatatt aacatggagg
1261 gcattgcatg aggtctgcca gaaggccctg cgtgtggatg gtgacacaga ggatggctct
1321 atgctggtga ctggacacat cgcctctggt taaatctctc ctgcttggcg acttcagtaa
1381 gctacagcta agcccatcgg ccggaaaaga aagacaataa ttttgttttt cattttgaaa
1441 aaattaaatg ctctctccta aagattcttc acctacaaaa aaaaaaaaaa aaaaaaaaaa
1501 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//