LOCUS BC063524 2864 bp mRNA linear HUM 23-DEC-2003
DEFINITION Homo sapiens retinoblastoma binding protein 6, mRNA (cDNA clone
IMAGE:4369701), partial cds.
ACCESSION BC063524
VERSION BC063524.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2864)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2864)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 134 Row: g Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 28077092.
FEATURES Location/Qualifiers
source 1..2864
/db_xref="H-InvDB:HIT000260982"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4369701"
/tissue_type="Bone, osteosarcoma"
/clone_lib="NIH_MGC_86"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..>2864
/gene="RBBP6"
/gene_synonym="DKFZp761B2423"
/gene_synonym="MY038"
/gene_synonym="RBQ-1"
/db_xref="GeneID:5930"
/db_xref="MIM:600938"
CDS 108..>2864
/gene="RBBP6"
/gene_synonym="DKFZp761B2423"
/gene_synonym="MY038"
/gene_synonym="RBQ-1"
/codon_start=1
/product="RBBP6 protein"
/protein_id="AAH63524.1"
/db_xref="GeneID:5930"
/db_xref="MIM:600938"
/translation="MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADC
DLQITNAQTKEEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPAMATTKAI
DDSSASISLAQLTKTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKPLGPPPPSYT
CFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGKY
AIPTIDAEAYAIGKKEKPPFLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCG
NSYCDECIRTALLESDEHTCPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRK
QLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIPVTSSSTHPAPSISSLTSNQS
SLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRTSSTGGSPVRKSEEKTDTKR
TVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASV
IKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDR
DYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSN
KDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLP
KKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNK
ESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFE
PDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSP
SVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKK"
misc_feature 585..635
/gene="RBBP6"
/gene_synonym="DKFZp761B2423"
/gene_synonym="MY038"
/gene_synonym="RBQ-1"
/note="zf-CCHC; Region: Zinc knuckle. The zinc knuckle is
a zinc binding motif composed of the the following
CX2CX4HX4C where X can be any amino acid. The motifs are
mostly from retroviral gag proteins (nucleocapsid).
Prototype structure is from HIV. Also contains members
involved in eukaryotic gene regulation, such as C. elegans
GLH-1. Structure is an 18-residue zinc finger"
/db_xref="CDD:pfam00098"
misc_feature 882..1004
/gene="RBBP6"
/gene_synonym="DKFZp761B2423"
/gene_synonym="MY038"
/gene_synonym="RBQ-1"
/note="RING; Region: Ring finger"
/db_xref="CDD:smart00184"
BASE COUNT 1080 a 581 c 543 g 660 t
ORIGIN
1 gtctttgagt gttttgtgtg tacatatttt gctcttaaag tttataaata tacgtatatt
61 gagagtgtcc acgtctcctc gctgaacctt aggaatccct tggcaccatg tcctgtgtgc
121 attataaatt ttcctctaaa ctcaactatg ataccgtcac ctttgatggg ctccacatct
181 ccctctgcga cttaaagaag cagattatgg ggagagagaa gctgaaagct gccgactgcg
241 acctgcagat caccaatgcg cagacgaaag aagaatatac tgatgataat gctctgattc
301 ctaagaattc ttctgtaatt gttagaagaa ttcctattgg aggtgttaaa tctacaagca
361 agacatatgt tataagtcga actgaaccag cgatggcaac tacaaaagca attgatgact
421 cttccgcgtc tatttctctg gcccagctta caaagactgc caatctggct gaagccaatg
481 cttctgaaga agataaaatt aaagcaatga tgtcgcaatc tggccatgaa tacgacccaa
541 tcaattacat gaagaaacct ctaggtccac cacctccatc ttacacgtgt ttccgttgtg
601 gtaaacctgg acattatatt aagaattgcc caacaaatgg ggataaaaac tttgaatctg
661 gtcctaggat taaaaagagc actggaattc ccagaagttt catgatggaa gtgaaagatc
721 ctaatatgaa aggtgcaatg cttaccaaca ctggaaaata tgcaatacca actatagatg
781 cagaagcata tgcaattggg aagaaagaga aacctccctt cttaccagag gagccatctt
841 cttcctcaga agaagatgat cctatcccag atgaattgtt gtgtctcatc tgcaaggata
901 ttatgactga tgctgttgtg attccctgct gtggaaacag ttactgtgat gaatgtataa
961 gaacagcact cctggaatca gatgagcaca catgtccgac gtgtcatcaa aatgatgttt
1021 ctcctgatgc tttaattgcc aataaatttt tacgacaggc tgtaaataac ttcaaaaatg
1081 aaactggcta tacaaaaaga ctacgaaaac agttacctcc tccaccaccc ccaataccac
1141 ctccgagacc actgattcag aggaacctac aacctctgat gagatctccg atatcaagac
1201 aacaagatcc tcttatgatt ccagtgacat cttcatcaac tcacccagct ccgtctatat
1261 cttcattaac ttctaatcag tcttccttgg cccctcctgt gtctggaaat ccgtcttctg
1321 ctccagctcc tgtacctgat ataactgcaa cagtatccat atcagttcat tcagaaaaat
1381 cagatggacc ttttcgtacg agctcaactg gaggcagtcc tgtgcggaaa tctgaagaaa
1441 aaacagatac aaagcgaact gtgattaaaa cgatggaaga atataataat gacaataccg
1501 cgccagctga agatgttatc attatgattc aggttcctca atccaaatgg gataaagatg
1561 actttgaatc tgaagaagaa gatgttaaat ccacacagcc tatatcaagt gtaggaaaac
1621 ctgctagtgt tataaaaaat gttagtacaa agccatcaaa tatagtcaag tatcctgaga
1681 aagaaagtga gccatccgag aaaattcaga aattcaccaa ggacgtgagc catgaaatca
1741 tacaacatga ggttaaaagt tcaaaaaact ctgcatctag tgaaaaaggg aaaaccaaag
1801 atcgagatta ttcagtgttg gaaaaggaga accctgaaaa gaggaagaac agcactcagc
1861 cagagaaaga gagtaatttg gaccgtctga atgaacaagg aaattttaaa agtctgtctc
1921 aatcttccaa agaggctaga acgtcagata aacatgattc cactcgtgct tcctcaaata
1981 aagacttcac tcccaataga gacaaaaaaa ctgactatga caccagagag tattcaagtt
2041 ccaaacgtag agatgaaaag aatgaattaa caagacgaaa agactctcct tctcggaata
2101 aagattctgc atctggacag aaaaataaac caagggaaga gagagatttg cctaaaaaag
2161 gaacaggaga ttccaaaaaa agtaattcta gtccctcaag agacagaaaa cctcatgatc
2221 acaaagccac ttatgatact aaacggccaa atgaagagac aaaatctgta gataaaaatc
2281 cttgtaagga tcgtgagaag catgtattag aagcaaggaa caataaagag tcaagtggca
2341 ataaactact ttatatactt aacccaccag agacacaggt tgaaaaagag caaattactg
2401 ggcaaattga caagagtact gtcaagccta aaccccagtt aagtcattcc tctagacttt
2461 cctctgactt aactagagaa actgatgaag ctgcttttga accagactat aatgaaagtg
2521 acagtgaaag taatgtttct gtaaaagaag aggaatcttc aggaaacatt tctaaggacc
2581 tgaaagataa aatagtggag aaagcaaaag agagcctgga cacagcagca gttgtccagg
2641 tgggcataag caggaatcag agccacagca gccccagcgt cagccccagc agaagccaca
2701 gtccttctgg aagccagacc cgaagccaca gtagcagtgc cagctcagca gaaagtcagg
2761 acagcaagaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2821 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//