LOCUS BC063480 1763 bp mRNA linear HUM 21-JUL-2005
DEFINITION Homo sapiens cancer susceptibility candidate 4, mRNA (cDNA clone
MGC:74708 IMAGE:5218924), complete cds.
ACCESSION BC063480
VERSION BC063480.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1763)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1763)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 135 Row: j Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 29826288.
FEATURES Location/Qualifiers
source 1..1763
/db_xref="H-InvDB:HIT000260939"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:74708 IMAGE:5218924"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1763
/gene="CASC4"
/gene_synonym="H63"
/db_xref="GeneID:113201"
CDS 274..1575
/gene="CASC4"
/gene_synonym="H63"
/codon_start=1
/product="CASC4 protein"
/protein_id="AAH63480.1"
/db_xref="GeneID:113201"
/translation="MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQE
EVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLG
KRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEY
ESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIP
KVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISV
SQHESHQAISHLPTGQPLSPNMPPDSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEP
RIQTDILKQATKDRVSDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEYEAD
KQAELAYNEEEDGDGGEEDVQGERGPGLHAITMKPTSKFFG"
BASE COUNT 495 a 424 c 468 g 376 t
ORIGIN
1 ctggcagctg ggttctcccg gttcccttgg gcaggtgcag ggtcgggttc aaagcctccg
61 gaacgcgttt tggcctgatt tgaggagggg ggcggggagg gacctgcggc ttgcggcccc
121 gcccccttct ccggctcgca gccgaccggt aagcccgcct cctccctcgg ccggccctgg
181 ggccgtgtcc gccgggcaac tccagccgag gcctgggctt ctgcctgcag gtgtctgcgg
241 cgaggcccct agggtacagc ccgatttggc cccatggtgg gtttcggggc caaccggcgg
301 gctggccgcc tgccctctct cgtgctggtg gtgctgctgg tggtgatcgt cgtcctcgcc
361 ttcaactact ggagcatctc ctcccgccac gtcctgcttc aggaggaggt ggccgagctg
421 cagggccagg tccagcgcac cgaagtggcc cgcgggcggc tggaaaagcg caattcggac
481 ctcttgctgt tggtggacac gcacaagaaa cagatcgacc agaaggaggc cgactacggc
541 cgcctcagca gccggctgca ggccagagag ggcctcggga agagatgcga ggatgacaag
601 gttaaactac agaacaacat atcgtatcag atggcagaca tacatcattt aaaggagcaa
661 cttgctgagc ttcgtcagga atttcttcga caagaagacc agcttcagga ctataggaag
721 aacaatactt accttgtgaa gaggttagaa tatgaaagtt ttcagtgtgg acagcagatg
781 aaggaattga gagcacagca tgaagaaaat attaaaaagt tagcagacca gtttttagag
841 gaacaaaagc aagagaccca aaagattcaa tcaaatgatg gaaaggaatt ggatataaac
901 aatcaagtag tacctaaaaa tattccaaaa gtagctgaga atgttgcaga taagaatgaa
961 gaaccctcaa gcaatcatat tccacatggg aaagaacaaa tcaaaagagg tggtgatgca
1021 gggatgcctg gaatagaaga gaatgaccta gcaaaagttg atgatcttcc ccctgcttta
1081 aggaagcctc ctatttcagt ttctcaacat gaaagtcatc aagcaatctc ccatcttcca
1141 actggacaac ctctctcccc aaatatgcct ccagattcac acataaacca caatggaaac
1201 cccggtactt caaaacagaa tccttccagt cctcttcagc gtttaattcc aggctcaaac
1261 ttggacagtg aacccagaat tcaaacagat atactaaagc aggctaccaa ggacagagtc
1321 agtgatttcc ataaattgaa gcaaagccga ttctttgatg aaaatgaatc ccctgttgat
1381 ccgcagcatg gctctaaact ggcggattat aatggggatg atggtaacgt aggtgagtat
1441 gaggcagaca agcaggctga gctggcttac aatgaggaag aagatggtga tggtggagag
1501 gaagacgtcc aaggtgagcg tgggcctggc ctccatgcta taaccatgaa acccacctct
1561 aagttttttg gttgaatttg tgtagaattt cccccactta ttagtggcag tgtaacctaa
1621 attttttgtt ttttctttgt gacggaattt cgcttgaacc cgggaggcgg aggttgcaat
1681 gagccgaatt cgtgccactg cactccagcc tgggcaacag agcaagactt cgtctaaaaa
1741 aaaaaaaaaa aaaaaaaaaa aaa
//