LOCUS BC063243 2331 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens protein phosphatase 1A (formerly 2C),
magnesium-dependent, alpha isoform, mRNA (cDNA clone MGC:60254
IMAGE:6011486), complete cds.
ACCESSION BC063243
VERSION BC063243.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2331)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2331)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 110 Row: h Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 29557854.
FEATURES Location/Qualifiers
source 1..2331
/db_xref="H-InvDB:HIT000260793"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:60254 IMAGE:6011486"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_68"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2331
/gene="PPM1A"
/gene_synonym="MGC9201"
/gene_synonym="PP2C-ALPHA"
/gene_synonym="PP2CA"
/db_xref="GeneID:5494"
/db_xref="HGNC:HGNC:9275"
/db_xref="MIM:606108"
CDS 234..1382
/gene="PPM1A"
/gene_synonym="MGC9201"
/gene_synonym="PP2C-ALPHA"
/gene_synonym="PP2CA"
/codon_start=1
/product="protein phosphatase 1A (formerly 2C),
magnesium-dependent, alpha isoform"
/protein_id="AAH63243.1"
/db_xref="GeneID:5494"
/db_xref="HGNC:HGNC:9275"
/db_xref="MIM:606108"
/translation="MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVI
GLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIR
TGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFF
TQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPE
PEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCL
YKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLECRVEEIIKKQGEGVPDLVHVM
RTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDDTDSTSTDDMW"
BASE COUNT 708 a 464 c 538 g 621 t
ORIGIN
1 gatgatctga gccgcgaggg cgccgacagc cgggggcccg gacgcagccc ggctcctccc
61 ctcctccgcc ccttccccag cctgacctgg cccgccgctg cagcggtgac ccctcccccg
121 gctgccgccg tcgccgccgc ggtgaccccc tccccggctg ccgccgccgc cgcctcggcc
181 gaccagggac ctgcccgcct gcggctgctc cggacctaga ggatcaagac ataatgggag
241 catttttaga caagccaaag atggaaaagc ataatgccca ggggcagggt aatgggttgc
301 gatatgggct aagcagcatg caaggctggc gtgttgaaat ggaggatgca catacggctg
361 tgatcggttt gccaagtgga cttgaatcgt ggtcattctt tgctgtgtat gatgggcatg
421 ctggttctca ggttgccaaa tactgctgtg agcatttgtt agatcacatc accaataacc
481 aggattttaa agggtctgca ggagcacctt ctgtggaaaa tgtaaagaat ggaatcagaa
541 caggttttct ggagattgat gaacacatga gagttatgtc agagaagaaa catggtgcag
601 atagaagtgg gtcaacagct gtaggtgtct taatttctcc ccaacatact tatttcatta
661 actgtggaga ctcaagaggt ttactttgta ggaacaggaa agttcatttc ttcacacaag
721 atcacaaacc aagtaatccg ctggagaaag aacgaattca gaatgcaggt ggctctgtaa
781 tgattcagcg tgtgaatggc tctctggctg tatcgagggc ccttggggat tttgattaca
841 aatgtgtcca tggaaaaggt cctactgagc agcttgtctc accagagcct gaagtccatg
901 atattgaaag atctgaagaa gatgatcagt tcattatcct tgcatgtgat ggtatctggg
961 atgttatggg aaatgaagag ctctgtgatt ttgtaagatc cagacttgaa gtcactgatg
1021 accttgagaa agtttgcaat gaagtagtcg acacctgttt gtataaggga agtcgagaca
1081 acatgagtgt gattttgatc tgttttccaa atgcacccaa agtatcgcca gaagcagtga
1141 agaaggaggc agagttggac aagtacctgg aatgcagagt agaagaaatc ataaagaagc
1201 agggggaagg cgtccccgac ttagtccatg tgatgcgcac attagcgagt gagaacatcc
1261 ccagcctccc accagggggt gaattggcaa gcaagaggaa tgttattgaa gccgtttaca
1321 atagactgaa tccttacaaa aatgacgaca ctgactctac atcaacagat gatatgtggt
1381 aaaactgctc atctagccat ggagtttacc ttcacctcca aaggagagta cagctcaact
1441 ttgttgaaac ttttaacatc catcctcaac tttaaggaag gggatatgac atgggtgaga
1501 atgattacat cagagaactt cagcagtaca acagctagcc cagaactgat tttttttttt
1561 ttttttgtaa atttgagact tatgtaagcg tgatttcaaa ccataattcg tgttgtaaat
1621 cagactccag caatttttgt tgtatgattt tgtttttttg taaagtgtaa ttgtccttgt
1681 acaaaatgct catatttaat tatgaactgc tttaaatcac tatcaaagtt acaagaaatg
1741 tttggcttat tgtgtgatgc aacagatata tagccctttc aagtcatgtt gtgtttggac
1801 ttggggttgg aacagggaga gcagcagcca tgtcagctac acgctcaaat gtgcagatga
1861 ttatggaaaa taacctcaaa atcttacaaa gctgaacatc caaggagtta ttgaaaacta
1921 tcttaaatgt tcttggtagg ggagttggca ttgttgataa agccagtccc ttcatttaac
1981 tgtctttcag gatgttcctt cgttgtttcc atgagtattg caggtaataa tacagtgtat
2041 tcataagaat ctcaatcttg gggctaaatg ccttgtttct ttgcacctct tttcaagtcc
2101 ttacatttaa ttactaattg ataagcagca gcttcctaca tatagtagga aactgccaca
2161 tttttgctat catgattggc tgggcctgct gctgttccta gtaagatatt ctgaattcca
2221 ttttatcaat aaagcttgat ttaacaaaca aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2281 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
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