LOCUS BC063123 2260 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2B, mRNA
(cDNA clone MGC:71977 IMAGE:30321290), complete cds.
ACCESSION BC063123
VERSION BC063123.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2260)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2260)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-DEC-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Michael Brownstein and Dr. Miklos Palkovits
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 51 Row: a Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40254430.
FEATURES Location/Qualifiers
source 1..2260
/db_xref="H-InvDB:HIT000260770"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71977 IMAGE:30321290"
/tissue_type="Skin and meninges pool- skin, dura matter,
pia matter, choroid plexus."
/clone_lib="NIH_MGC_186"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..2260
/gene="HTR2B"
/gene_synonym="5-HT(2B)"
/gene_synonym="5-HT2B"
/db_xref="GeneID:3357"
/db_xref="HGNC:HGNC:5294"
/db_xref="MIM:601122"
CDS 510..1955
/gene="HTR2B"
/gene_synonym="5-HT(2B)"
/gene_synonym="5-HT2B"
/codon_start=1
/product="5-hydroxytryptamine (serotonin) receptor 2B"
/protein_id="AAH63123.1"
/db_xref="GeneID:3357"
/db_xref="HGNC:HGNC:5294"
/db_xref="MIM:601122"
/translation="MALSYRVSELQSTIPEHILQSTFVHVISSNWSGLQTESIPEEMK
QIVEEQGNKLHWAALLILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLL
VGLFVMPIALLTIMFEAMWPLPLVLCPAWLFLDVLFSTASIMHLCAISVDRYIAIKKP
IQANQYNSRATAFIKITVVWLISIGIAIPVPIKGIETDVDNPNNITCVLTKERFGDFM
LFGSLAAFFTPLAIMIVTYFLTIHALQKKAYLVKNKPPQRLTWLTVSTVFQRDETPCS
SPEKVAMLDGSRKDKALPNSGDETLMRRTSTIGKKSVQTISNEQRASKVLGIVFFLFL
LMWCPFFITNITLVLCDSCNQTTLQMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFG
RYITCNYRATKSVKTLRKRSSKIYFRNPMAENSKFFKKHGIRNGINPAMYQSPMRLRS
STIQSSSIILLDTLLLTENEGDKTEERVSYV"
BASE COUNT 714 a 457 c 437 g 652 t
ORIGIN
1 gggggtattt gtttcactgc tttcaaccgc ctgtgctgga ggctcagaat aagtcaatgg
61 gaggaggatt tcagtcacag cagcaagcaa gtctagtgaa cagataagat gacatgctca
121 gcaaaataac aacgaaacca gagggggaac tctctggcat gcaagttcaa acacgactct
181 acaactacgg cagaaaaaga gagagagaga aactaaaaat atatatatat cctatttttt
241 tcacagctat cagtttcttt cactgagctt tcctaaattt aagcctctag aaaataataa
301 atacttggat atcttaccta caaacatgga cagatgtgtg tatgcgctca ttttagagaa
361 cttgaatttt tttttttaaa ggaaggtgtc aactttggct tttgagtgtt tggcatggtt
421 acaatgcctt aaaaaaacag atgagcagct tagctactaa ccatgctgac cactgttcgg
481 aacgggattg aatcacagaa aaacagcaaa tggctctctc ttacagagtg tctgaacttc
541 aaagcacaat tcctgagcac attttgcaga gcacctttgt tcacgttatc tcttctaact
601 ggtctggatt acagacagaa tcaataccag aggaaatgaa acagattgtt gaggaacagg
661 gaaataaact gcactgggca gctcttctga tactcatggt gataataccc acaattggtg
721 gaaataccct tgttattctg gctgtttcac tggagaagaa gctgcagtat gctactaatt
781 actttctaat gtccttggcg gtggctgatt tgctggttgg attgtttgtg atgccaattg
841 ccctcttgac aataatgttt gaggctatgt ggcccctccc acttgttcta tgtcctgcct
901 ggttatttct tgacgttctc ttttcaaccg catccatcat gcatctctgt gccatttcag
961 tggatcgtta catagccatc aaaaagccaa tccaggccaa tcaatataac tcacgggcta
1021 cagcattcat caagattaca gtggtgtggt taatttcaat aggcattgcc attccagtcc
1081 ctattaaagg gatagagact gatgtggaca acccaaacaa tatcacttgt gtgctgacaa
1141 aggaacgttt tggcgatttc atgctctttg gctcactggc tgccttcttc acacctcttg
1201 caattatgat tgtcacctac tttctcacta tccatgcttt acagaagaag gcttacttag
1261 tcaaaaacaa gccacctcaa cgcctaacat ggttgactgt gtctacagtt ttccaaaggg
1321 atgaaacacc ttgctcgtca ccggaaaagg tggcaatgct ggatggttct cgaaaggaca
1381 aggctctgcc caactcaggt gatgaaacac ttatgcgaag aacatccaca attgggaaaa
1441 agtcagtgca gaccatttcc aacgaacaga gagcctcaaa ggtcctaggg attgtgtttt
1501 tcctcttttt gcttatgtgg tgtcccttct ttattacaaa tataacttta gttttatgtg
1561 attcctgtaa ccaaactact ctccaaatgc tcctggagat atttgtgtgg ataggctatg
1621 tttcctcagg agtgaatcct ttggtctaca ccctcttcaa taagacattt cgggatgcat
1681 ttggccgata tatcacctgc aattaccggg ccacaaagtc agtaaaaact ctcagaaaac
1741 gctccagtaa gatctacttc cggaatccaa tggcagagaa ctctaagttt ttcaagaaac
1801 atggaattcg aaatgggatt aaccctgcca tgtaccagag tccaatgagg ctccgaagtt
1861 caaccattca gtcttcatca atcattctac tagatacgct tctcctcact gaaaatgaag
1921 gtgacaaaac tgaagagcga gttagttatg tatagcagaa ctggcagttg tcatcaaaca
1981 taatgatgag taagatgatg aatgagatgt aaatgtgcca agaatatatt atataaagaa
2041 ttttatgtca tatatcaaat catctcttta acctaagatg taagtattaa gaatatctaa
2101 ttttcctaat ttggacaaga ttattccatg aggaaaataa ttttatatag ctacaaatga
2161 aaacaatcca gcactctggt taaattttaa ggtattcgaa tgaaataaag tcaaatcaat
2221 aaatttcagg ccaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//