LOCUS BC062701 1098 bp mRNA linear HUM 11-DEC-2003 DEFINITION Homo sapiens aquaporin 7, mRNA (cDNA clone MGC:71981 IMAGE:30324263), complete cds. ACCESSION BC062701 VERSION BC062701.1 KEYWORDS MGC. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 1098) AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A. TITLE Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) PUBMED 12477932 REFERENCE 2 (bases 1 to 1098) AUTHORS Strausberg,R. TITLE Direct Submission JOURNAL Submitted (25-NOV-2003) National Institutes of Health, Mammalian Gene Collection (MGC), Cancer Genomics Office, National Cancer Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590, USA REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov COMMENT Contact: MGC help desk Email: cgapbs-r@mail.nih.gov Tissue Procurement: Dr. Michael Brownstein and Dr. Miklos Palkovits cDNA Library Preparation: CLONTECH Laboratories, Inc. cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) DNA Sequencing by: Genome Sequence Centre, BC Cancer Agency, Vancouver, BC, Canada info@bcgsc.bc.ca Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield, Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin, Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott, Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy, George Yang, Scott Zuyderduyn, Marco Marra. Clone distribution: MGC clone distribution information can be found through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov Series: IRAL Plate: 51 Row: a Column: 10 This clone was selected for full length sequencing because it passed the following selection criteria: matched mRNA gi: 4502186. FEATURES Location/Qualifiers source 1..1098 /db_xref="H-InvDB:HIT000260592" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /clone="MGC:71981 IMAGE:30324263" /tissue_type="Skin and meninges pool- skin, dura matter, pia matter, choroid plexus." /clone_lib="NIH_MGC_186" /lab_host="DH10B" /note="Vector: pDNR-LIB" gene 1..1098 /gene="AQP7" /gene_synonym="AQP7L" /gene_synonym="AQP9" /gene_synonym="AQPap" /db_xref="GeneID:364" /db_xref="MIM:602974" CDS 216..866 /gene="AQP7" /gene_synonym="AQP7L" /gene_synonym="AQP9" /gene_synonym="AQPap" /codon_start=1 /product="AQP7 protein" /protein_id="AAH62701.1" /db_xref="GeneID:364" /db_xref="MIM:602974" /translation="MVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFAN CALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFA TYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSL GMNTGYAINPSRDLPPRIFTFIAGWGKQVFRWHHLPGLHWLHHPTGAPEIGGFCGV" misc_feature 219..764 /gene="AQP7" /gene_synonym="AQP7L" /gene_synonym="AQP9" /gene_synonym="AQPap" /note="MIP; Region: Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms" /db_xref="CDD:cd00333" BASE COUNT 260 a 312 c 287 g 239 t ORIGIN 1 gggggacaca gggatagctg agccccagct gggggtggaa gctgagccag ggacagtcac 61 ggaggaacaa gatcaagatg cgctgtaact gagaagcccc caaggcggag gctgagaatc 121 agagacattt cagcagacat ctacaaatct gaaagacaaa acatggttca agcatccggg 181 cacaggcggt attcggcctt ggttccgtgg cccatatggt tctaaataaa aaatatggga 241 gctaccttgg tgtcaacttg ggttttggct tcggagtcac catgggagtg cacgtggcag 301 gccgcatctc tggagcccac atgaacgcag ctgtgacctt tgctaactgt gcgctgggcc 361 gcgtgccctg gaggaagttt ccggtctatg tgctggggca gttcctgggc tccttcctgg 421 cggctgccac catctacagt ctcttctaca cggccattct ccacttttcg ggtggacagc 481 tgatggtgac cggtcccgtc gctacagctg gcatttttgc cacctacctt cctgatcaca 541 tgacattgtg gcggggcttc ctgaatgagg cgtggctgac cgggatgctc cagctgtgtc 601 tcttcgccat cacggaccag gagaacaacc cagcactgcc aggaacagag gcgctggtga 661 taggcatcct cgtggtcatc atcggggtgt cccttggcat gaacacagga tatgccatca 721 acccgtcccg ggacctgccc ccccgcatct tcaccttcat tgctggttgg ggcaaacagg 781 tcttcaggtg gcatcatcta cctggtcttc attggctcca ccatcccacg ggagcccctg 841 aaattggagg attctgtggc gtatgaagac cacgggataa ccgtattgcc caagatggga 901 tctcatgaac ccacgatctc tcccctcacc cccgtctctg tgagccctgc caacagatct 961 tcagtccacc ctgccccacc cttacatgaa tccatggccc tagagcactt ctaagcagag 1021 attatttgtg atcccatcca ttccccaata aagcaaggct tgtccgtcaa aaaaaaaaaa 1081 aaaaaaaaaa aaaaaaaa //