LOCUS BC062581 2550 bp mRNA linear HUM 06-JUN-2006
DEFINITION Homo sapiens CD276 molecule, mRNA (cDNA clone MGC:74893
IMAGE:5201491), complete cds.
ACCESSION BC062581
VERSION BC062581.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2550)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2550)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 135 Row: g Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 67188442.
FEATURES Location/Qualifiers
source 1..2550
/db_xref="H-InvDB:HIT000260493"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:74893 IMAGE:5201491"
/tissue_type="Lung, Spleen, fetal, pooled"
/clone_lib="NIH_MGC_122"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2550
/gene="CD276"
/gene_synonym="B7-H3"
/gene_synonym="B7H3"
/db_xref="GeneID:80381"
/db_xref="HGNC:HGNC:19137"
/db_xref="MIM:605715"
CDS 235..1716
/gene="CD276"
/gene_synonym="B7-H3"
/gene_synonym="B7H3"
/codon_start=1
/product="CD276 protein"
/protein_id="AAH62581.1"
/db_xref="GeneID:80381"
/db_xref="HGNC:HGNC:19137"
/db_xref="MIM:605715"
/translation="MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGT
DATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQ
GNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDT
VTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTY
SCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGF
SLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVAD
EGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEA
EVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAH
GSVTITGQPMTFPPGPASSAVPLSPAHPPHGSMCWSHWFSRGL"
BASE COUNT 514 a 804 c 761 g 471 t
ORIGIN
1 ccggcctcag ggacgcaccg gagccgcctt tccgggcctc aggcggattc tccggcgcgg
61 cccgccccgc ccctcggact ccccgggccg cccccggccc ccattcgggc cgggcctcgc
121 tgcggcggcg actgagccag gctgggccgc gtccctgagt cccagagtcg gcgcggcgcg
181 gcaggggcag ccttccacca cggggagccc agctgtcagc cgcctcacag gaagatgctg
241 cgtcggcggg gcagccctgg catgggtgtg catgtgggtg cagccctggg agcactgtgg
301 ttctgcctca caggagccct ggaggtccag gtccctgaag acccagtggt ggcactggtg
361 ggcaccgatg ccaccctgtg ctgctccttc tcccctgagc ctggcttcag cctggcacag
421 ctcaacctca tctggcagct gacagatacc aaacagctgg tgcacagctt tgctgagggc
481 caggaccagg gcagcgccta tgccaaccgc acggccctct tcccggacct gctggcacag
541 ggcaacgcat ccctgaggct gcagcgcgtg cgtgtggcgg acgagggcag cttcacctgc
601 ttcgtgagca tccgggattt cggcagcgct gccgtcagcc tgcaggtggc cgctccctac
661 tcgaagccca gcatgaccct ggagcccaac aaggacctgc ggccagggga cacggtgacc
721 atcacgtgct ccagctacca gggctaccct gaggctgagg tgttctggca ggatgggcag
781 ggtgtgcccc tgactggcaa cgtgaccacg tcgcagatgg ccaacgagca gggcttgttt
841 gatgtgcaca gcatcctgcg ggtggtgctg ggtgcaaatg gcacctacag ctgcctggtg
901 cgcaaccccg tgctgcagca ggatgcgcac agctctgtca ccatcacacc ccagagaagc
961 cccacaggag ccgtggaggt ccaggtccct gaggacccgg tggtggccct agtgggcacc
1021 gatgccaccc tgcgctgctc cttctccccc gagcctggct tcagcctggc acagctcaac
1081 ctcatctggc agctgacaga caccaaacag ctggtgcaca gtttcaccga aggccgggac
1141 cagggcagcg cctatgccaa ccgcacggcc ctcttcccgg acctgctggc acaaggcaat
1201 gcatccctga ggctgcagcg cgtgcgtgtg gcggacgagg gcagcttcac ctgcttcgtg
1261 agcatccggg atttcggcag cgctgccgtc agcctgcagg tggccgctcc ctactcgaag
1321 cccagcatga ccctggagcc caacaaggac ctgcggccag gggacacggt gaccatcacg
1381 tgctccagct accggggcta ccctgaggct gaggtgttct ggcaggatgg gcagggtgtg
1441 cccctgactg gcaacgtgac cacgtcgcag atggccaacg agcagggctt gtttgatgtg
1501 cacagcgtcc tgcgggtggt gctgggtgcg aatggcacct acagctgcct ggtgcgcaac
1561 cccgtgctgc agcaggatgc gcacggctct gtcaccatca cagggcagcc tatgacattc
1621 ccccctggcc cagcctcctc tgcagtgccc ctctcccctg cccatcctcc ccacggaagc
1681 atgtgctggt cacactggtt ctccaggggt ctgtgatggg gcccctgggg gtcagcttct
1741 gtccctctgc cttctcacct ctttgttcct ttcttttcat gtatccattc agttgatgtt
1801 tattgagcaa ctacagatgt cagcactgtg ttaggtgctg ggggccctgc gtgggaagat
1861 aaagttcctc cctcaaggac tccccatcca gctgggagac agacaactaa ctacactgca
1921 ccctgcggtt tgcagggggc tcctgcctgg ctccctgctc cacacctcct ctgtggctca
1981 aggcttcctg gatacctcac ccccatccca cccataattc ttacccagag catggggttg
2041 gggcggaaac ctggagagag ggacatagcc cctcgccacg gctagagaat ctggtggtgt
2101 ccaaaatgtc tgtccaggtg tgggcaggtg ggcaggcacc aaggccctct ggacctttca
2161 tagcagcaga aaaggcagag cctggggcag ggcagggcca ggaatgcttt ggggacaccg
2221 aggggactgc cccccacccc caccatggtg ctattctggg gctggggcag tcttttcctg
2281 gcttgcctct ggccagctcc tggcctctgg tagagtgaga cttcagacgt tctgatgcct
2341 tccggatgtc atctctccct gccccaggaa tggaagatgt gaggacttct aatttaaatg
2401 tgggactcgg agggattttg taaactgggg gtatattttg gggaaaataa atgtctttgt
2461 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2521 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//