LOCUS BC062429 1322 bp mRNA linear HUM 11-DEC-2003
DEFINITION Homo sapiens breast cancer 1, early onset, mRNA (cDNA clone
IMAGE:3686198), partial cds.
ACCESSION BC062429
VERSION BC062429.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1322)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1322)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (17-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 51 Row: c Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6552304.
FEATURES Location/Qualifiers
source 1..1322
/db_xref="H-InvDB:HIT000260392"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3686198"
/tissue_type="Bladder, carcinoma"
/clone_lib="NIH_MGC_53"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene <1..>1322
/gene="BRCA1"
/gene_synonym="PSCP"
/gene_synonym="RNF53"
/db_xref="GeneID:672"
/db_xref="MIM:113705"
CDS <1..>1322
/gene="BRCA1"
/gene_synonym="PSCP"
/gene_synonym="RNF53"
/codon_start=3
/product="BRCA1 protein"
/protein_id="AAH62429.1"
/db_xref="GeneID:672"
/db_xref="MIM:113705"
/translation="GLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERHPEK
YQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQH
NRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKRKLPCSENPRDTEDVPWITLN
SSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVDEYSGSSEKIDLLAS
DPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQI
IQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITN
SGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKK
NRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSKKKKKKKKKK"
BASE COUNT 508 a 227 c 280 g 307 t
ORIGIN
1 ggggtttgga ttctgcaaaa aaggctgctt gtgaattttc tgagacggat gtaacaaata
61 ctgaacatca tcaacccagt aataatgatt tgaacaccac tgagaagcgt gcagctgaga
121 ggcatccaga aaagtatcag ggtagttctg tttcaaactt gcatgtggag ccatgtggca
181 caaatactca tgccagctca ttacagcatg agaacagcag tttattactc actaaagaca
241 gaatgaatgt agaaaaggct gaattctgta ataaaagcaa acagcctggc ttagcaagga
301 gccaacataa cagatgggct ggaagtaagg aaacatgtaa tgataggcgg actcccagca
361 cagaaaaaaa ggtagatctg aatgctgatc ccctgtgtga gagaaaagaa tggaataagc
421 ggaaactgcc atgctcagag aatcctagag atactgaaga tgttccttgg ataacactaa
481 atagcagcat tcagaaagtt aatgagtggt tttccagaag tgatgaactg ttaggttctg
541 atgactcaca tgatggggag tctgaatcaa atgccaaagt agctgatgta ttggacgttc
601 taaatgaggt agatgaatat tctggttctt cagagaaaat agacttactg gccagtgatc
661 ctcatgaggc tttaatatgt aaaagtgaaa gagttcactc caaatcagta gagagtaata
721 ttgaagacaa aatatttggg aaaacctatc ggaagaaggc aagcctcccc aacttaagcc
781 atgtaactga aaatctaatt ataggagcat ttgttactga gccacagata atacaagagc
841 gtcccctcac aaataaatta aagcgtaaaa ggagacccac atcaggcctt catcctgagg
901 attttatcaa gaaagcagat ttggcagttc aaaagactcc tgaaatgata aatcagggaa
961 ctaaccaaac ggagcagaat ggtcaagtga tgaatattac taatagtggt catgagaata
1021 aaacaaaagg tgattctatt cagaatgaga aaaatcctaa cccaatagaa tcactcgaaa
1081 aagaatctgc tttcaaaacg aaagctgaac ctataagcag cagtataagc aatatggaac
1141 tcgaattaaa tatccacaat tcaaaagcac ctaaaaagaa taggctgagg aggaagtctt
1201 ctaccaggca tattcatgcg cttgaactag tagtcagtag aaatctaagc ccacctaatt
1261 gtactgaatt gcaaattgat agttgttcta gcaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1321 aa
//