LOCUS BC062303 1631 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens stearoyl-CoA desaturase (delta-9-desaturase), mRNA
(cDNA clone MGC:71288 IMAGE:6586153), complete cds.
ACCESSION BC062303
VERSION BC062303.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1631)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1631)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (17-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 50 Row: o Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 53759150.
FEATURES Location/Qualifiers
source 1..1631
/db_xref="H-InvDB:HIT000260305"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71288 IMAGE:6586153"
/tissue_type="Breast, adenocarcinoma"
/clone_lib="NIH_MGC_107"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1631
/gene="SCD"
/gene_synonym="FADS5"
/gene_synonym="PRO0998"
/gene_synonym="SCD1"
/db_xref="GeneID:6319"
/db_xref="HGNC:HGNC:10571"
/db_xref="MIM:604031"
CDS 377..1456
/gene="SCD"
/gene_synonym="FADS5"
/gene_synonym="PRO0998"
/gene_synonym="SCD1"
/codon_start=1
/product="stearoyl-CoA desaturase (delta-9-desaturase)"
/protein_id="AAH62303.1"
/db_xref="GeneID:6319"
/db_xref="HGNC:HGNC:10571"
/db_xref="MIM:604031"
/translation="MPAHLLQDDISSSYTTTTTITAPPSRVLQNGGDKLETMPLYLED
DIRPDIKDDIYDPTYKDKEGPSPKVEYVWRNIILMSLLHLGALYGITLIPTCKFYTWL
WGVFYYFVSALGITAGAHRLWSHRSYKARLPLRLFLIIANTMAFQNDVYEWARDHRAH
HKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGSTLDLSDLEAEKLVMFQRRYY
KPGLLLMCFILPTLVPWYFWGETFQNSVFVATFLRYAVVLNATWLVNSAAHLFGYRPY
DKNISPRENILVSLGAVGEGFHNYHHSFPYDYSASEYRWHINFTTFFIDCMAALGLAY
DRKKVSKAAILARIKRTGDGNYKSG"
BASE COUNT 379 a 477 c 391 g 384 t
ORIGIN
1 gtcggtgtcg gcagcatccc cggcgccctg ctgcggtcgc cgcgagcctc ggcctctgtc
61 tcctccccct cccgccctta cctccacgcg ggaccgcccg cgccagtcaa ctcctcgcac
121 tttgcccctg cttggcagcg gataaaaggg ggctgaggaa ataccggaca cggtcacccg
181 ttgccagctc tagcctttaa attcccggct cggggacctc cacgcaccgc ggctagcgcc
241 gacaaccagc tagcgtgcaa ggcgccgcgg ctcagcgcgt accggcgggc ttcgaaaccg
301 cagtcctccg gcgaccccga actccgctcc ggagcctcag ccccctggaa agtgatcccg
361 gcatcggaga gccaagatgc cggcccactt gctgcaggac gatatctcta gctcctatac
421 caccaccacc accattacag cgcctccctc cagggtcctg cagaatggag gagataagtt
481 ggagacgatg cccctctact tggaagacga cattcgccct gatataaaag atgatatata
541 tgaccccacc tacaaggata aggaaggccc aagccccaag gttgaatatg tctggagaaa
601 catcatcctt atgtctctgc tacacttggg agccctgtat gggatcactt tgattcctac
661 ctgcaagttc tacacctggc tttggggggt attctactat tttgtcagtg ccctgggcat
721 aacagcagga gctcatcgtc tgtggagcca ccgctcttac aaagctcggc tgcccctacg
781 gctctttctg atcattgcca acacaatggc attccagaat gatgtctatg aatgggctcg
841 tgaccaccgt gcccaccaca agttttcaga aacacatgct gatcctcata attcccgacg
901 tggctttttc ttctctcacg tgggttggct gcttgtgcgc aaacacccag ctgtcaaaga
961 gaaggggagt acgctagact tgtctgacct agaagctgag aaactggtga tgttccagag
1021 gaggtactac aaacctggct tgctgctgat gtgcttcatc ctgcccacgc ttgtgccctg
1081 gtatttctgg ggtgaaactt ttcaaaacag tgtgttcgtt gccactttct tgcgatatgc
1141 tgtggtgctt aatgccacct ggctggtgaa cagtgctgcc cacctcttcg gatatcgtcc
1201 ttatgacaag aacattagcc cccgggagaa tatcctggtt tcacttggag ctgtgggtga
1261 gggcttccac aactaccacc actcctttcc ctatgactac tctgccagtg agtaccgctg
1321 gcacatcaac ttcaccacat tcttcattga ttgcatggcc gccctcggtc tggcctatga
1381 ccggaagaaa gtctccaagg ccgccatctt ggccaggatt aaaagaaccg gagatggaaa
1441 ctacaagagt ggctgagttt ggggtccctc aggttccttt ttcaaaaacc agccaggcag
1501 aggttttaat gtctgtttat taactactga ataatgctac caggatgcta aagatgatga
1561 tgttaaccca ttccagtaca gtattctttt aaaattcaaa agtattgaaa gccaaaaaaa
1621 aaaaaaaaaa a
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