LOCUS BC061587 1333 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens 2',5'-oligoadenylate synthetase 1, 40/46kDa, mRNA
(cDNA clone MGC:75005 IMAGE:6502031), complete cds.
ACCESSION BC061587
VERSION BC061587.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1333)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1333)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-NOV-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 141 Row: i Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8051620.
FEATURES Location/Qualifiers
source 1..1333
/db_xref="H-InvDB:HIT000260209"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:75005 IMAGE:6502031"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1333
/gene="OAS1"
/gene_synonym="IFI-4"
/gene_synonym="OIASI"
/db_xref="GeneID:4938"
/db_xref="HGNC:HGNC:8086"
/db_xref="MIM:164350"
CDS 32..1126
/gene="OAS1"
/gene_synonym="IFI-4"
/gene_synonym="OIASI"
/codon_start=1
/product="2',5'-oligoadenylate synthetase 1, 40/46kDa"
/protein_id="AAH61587.1"
/db_xref="GeneID:4938"
/db_xref="HGNC:HGNC:8086"
/db_xref="MIM:164350"
/translation="MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKER
CFRGSSYPVCVSKVVKGGSSGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEI
RRQLEACQRERAFSVKFEVQAPRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLT
GGYKPNPQIYVKLIEECTDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQN
CKKKLGKLPPQYALELLTVYAWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYY
DFKNPIIEKYLRRQLTKPRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKN
WDGSPVSSWILLVRPPASSLPFIPAPLHEA"
BASE COUNT 342 a 352 c 321 g 318 t
ORIGIN
1 ggcagttctg ttgccactct ctctcctgtc aatgatggat ctcagaaata ccccagccaa
61 atctctggac aagttcattg aagactatct cttgccagac acgtgtttcc gcatgcaaat
121 caaccatgcc attgacatca tctgtgggtt cctgaaggaa aggtgcttcc gaggtagctc
181 ctaccctgtg tgtgtgtcca aggtggtaaa gggtggctcc tcaggcaagg gcaccaccct
241 cagaggccga tctgacgctg acctggttgt cttcctcagt cctctcacca cttttcagga
301 tcagttaaat cgccggggag agttcatcca ggaaattagg agacagctgg aagcctgtca
361 aagagagaga gcattttccg tgaagtttga ggtccaggct ccacgctggg gcaacccccg
421 tgcgctcagc ttcgtactga gttcgctcca gctcggggag ggggtggagt tcgatgtgct
481 gcctgccttt gatgccctgg gtcagttgac tggcggctat aaacctaacc cccaaatcta
541 tgtcaagctc atcgaggagt gcaccgacct gcagaaagag ggcgagttct ccacctgctt
601 cacagaacta cagagagact tcctgaagca gcgccccacc aagctcaaga gcctcatccg
661 cctagtcaag cactggtacc aaaattgtaa gaagaagctt gggaagctgc cacctcagta
721 tgccctggag ctcctgacgg tctatgcttg ggagcgaggg agcatgaaaa cacatttcaa
781 cacagcccag ggatttcgga cggtcttgga attagtcata aactaccagc aactctgcat
841 ctactggaca aagtattatg actttaaaaa ccccattatt gaaaagtacc tgagaaggca
901 gctcacgaaa cccaggcctg tgatcctgga cccggcggac cctacaggaa acttgggtgg
961 tggagaccca aagggttgga ggcagctggc acaagaggct gaggcctggc tgaattaccc
1021 atgctttaag aattgggatg ggtccccagt gagctcctgg attctgctgg tgagacctcc
1081 tgcttcctcc ctgccattca tccctgcccc tctccatgaa gcttgagaca tatagctgga
1141 gaccattctt tccaaagaac ttacctcttg ccaaaggcca tttatattca tatagtgaca
1201 ggctgtgctc catattttac agtcattttg gtcacaatcg agggtttctg gaattttcac
1261 atcccttgtc cagaattcat tcccctaaga gtaataataa ataatctcta acaccgttaa
1321 aaaaaaaaaa aaa
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